The natural history of primary hyperparathyroidism with or without parathyroid surgery after 15 years

Journal of Clinical Endocrinology and Metabolism

Volumn 93, Issue 9, 2008, Pages 3462-3470

  Rubin, Mishaela R ^a   Bilezikian, John P ^a   McMahon, Donald J ^a   Jacobs, Thomas ^a   Shane, Elizabeth ^a   Siris, Ethel ^a   Udesky, Julia ^a   Silverberg, Shonni J ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BONE DENSITY; CORTICAL BONE; DISEASE COURSE; FEMALE; FEMUR NECK; HUMAN; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PARATHYROIDECTOMY; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; RADIUS;

EID: 51649095701     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-1215     Document Type: Article

References (40)

1. Albright F, Reifenstein EC 1948 The parathyroid glands and metabolic bone disease. Baltimore: Williams & Wilkins Co.
2. Heath 3rd H, Hodgson SF, Kennedy MA 1980 Primary hyperparathyroidism. Incidence, morbidity, and potential economic impact in a community. N Engl J Med 302:189-193
3. Silverberg SJ, Shane E, Jacobs TP, Siris E, Bilezikian JP 1999 A 10-year prospective study of primary hyperparathyroidism with or without parathyroid surgery. N Engl J Med 341:1249-1255
4. NIH conference 1991 Diagnosis and management of asymptomatic primary hyperparathyroidism: consensus development conference statement. Ann Intern Med 114:593-597
5. Locker FG, Silverberg SJ, Bilezikian JP 1997 Optimal dietary calcium intake in primary hyperparathyroidism. Am J Med 102:543-550
6. Nussbaum SR, Zahradnik RJ, Lavigne JR, Brennan GL, Nozawa-Ung K, Kim LY, Keutmann HT, Wang CA, Potts Jr JT, Segre GV 1987 Highly sensitive two-site immunoradiometric assay of parathyrin, and its clinical utility in evaluating patients with hypercalcemia. Clin Chem 33:1364-1367
7. Silverberg SJ, Shane E, de la Cruz L, Dempster DW, Feldman F, Seldin D, Jacobs TP, Siris ES, Cafferty M, Parisien MV, Bilezikian JP 1989 Skeletal disease in primary hyperparathyroidism. J Bone Miner Res 4:283-291
8. Parfitt AM 1990 Interpretation of bone densitometry measurements: disadvantages of a percentage scale and a discussion of some alternatives. J Bone Miner Res 5:537-540
9. Fang Z, Smith JA, Kleppinger A, Reisine ST, Emerson D, Kulldorff M 2002 Retrospective evaluation and adjustment of dual energy X-ray absorptiometry measurements for bone mineral density research studies. J Clin Densitom 5:421-433
10. Faulkner KG, McClung MR 1995 Quality control of DXA instruments in multicenter trials. Osteoporos Int 5:218-227
11. Liang K, Zeger S 1986 Longitudinal data analysis using generalized linear models. Biometrika 73:13-22
12. Kenward MG, Roger JH 1997 Small sample inference for fixed effects from restricted maximum likelihood. Biometrics 53:983-997
13. Eriksen EF, Mosekilde L, Melsen F 1986 Trabecular bone remodeling and balance in primary hyperparathyroidism. Bone 7:213-221
14. Dempster DW, Parisien M, Silverberg SJ, Liang XG, Schnitzer M, Shen V, Shane E, Kimmel DB, Recker R, Lindsay R, Bilezikian JP 1999 On the mechanism of cancellous bone preservation in postmenopausal women with mild primary hyperparathyroidism. J Clin Endocrinol Metab 84: 1562-1566
15. Parisien M, Mellish RW, Silverberg SJ, Shane E, Lindsay R, Bilezikian JP, Dempster DW 1992 Maintenance of cancellous bone connectivity in primary hyperparathyroidism: trabecular strut analysis. J Bone Miner Res 7:913-919
16. Parisien M, Silverberg SJ, Shane E, de la Cruz L, Lindsay R, Bilezikian JP, Dempster DW 1990 The histomorphometry of bone in primary hyperparathyroidism: preservation of cancellous bone structure. J Clin Endocrinol Metab 70:930-938
17. Parfitt AM 1986 Accelerated cortical loss: primary and secondary hyperparathyroidism. In: Uhthoff H, Stahl E, eds. Current concepts of bone fragility. Berlin: Springer-Verlag; 279-85
18. Rao DS, Wallace EA, Antonelli RF, Talpos GB, Ansari MR, Jacobsen G, Divine GW, Parfitt AM 2003 Forearm bone density in primary hyperparathyroidism: long-term follow-up with and without parathyroidectomy. Clin Endocrinol (Oxf) 58:348-354
19. Leppla DC, Snyder W, Pak CY 1982 Sequential changes in bone density before and after parathyroidectomy in primary hyperparathyroidism. Invest Radiol 17:604-606
20. Parfitt AM, Rao DS, Kleerekoper M 1991 Asymptomatic primary hyperparathyroidism discovered by multichannel biochemical screening: clinical course and considerations bearing on the need for surgical intervention. J Bone Miner Res 6(Suppl 2):S97-S101
21. Elvius M, Lagrelius A, Nygren A, Alveryd A, Christensson TA, Nordenstrom J 1995 Seventeen year follow-up study of bone mass in patients with mild asymptomatic hyperparathyroidism some of whom were operated on. Eur J Surg161:863-869
22. Rao DS, Wilson RJ, Kleerekoper M, Parfitt AM 1988 Lack of biochemical progression or continuation of accelerated bone loss in mild asymptomatic primary hyperparathyroidism: evidence for biphasic disease course. J Clin Endocrinol Metab 67:1294-1298
23. Silverberg SJ, Bilezikian JP 2003 "Incipient" primary hyperparathyroidism: a "forme fruste" of an old disease. J Clin Endocrinol Metab 88:5348-5352
24. Bilezikian JP, Silverberg SJ 2004 Clinical practice. Asymptomatic primary hyperparathyroidism. N Engl J Med 350:1746-1751
25. Bilezikian JP, Potts Jr JT, Fuleihan Gel H, Kleerekoper M, Neer R, Peacock M, Rastad J, Silverberg SJ, Udelsman R, Wells SA 2002 Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century. J Clin Endocrinol Metab 87:5353-5361
26. Christiansen P, Steiniche T, Mosekilde L, Hessov I, Melsen F 1990 Primary hyperparathyroidism: changes in trabecular bone remodeling following surgical treatment-evaluated by histomorphometric methods. Bone 11:75-79
27. Christiansen P, Steiniche T, Brixen K, Hessov I, Melsen F, Heickendorff L, Mosekilde L 1999 Primary hyperparathyroidism: short-term changes in bone remodeling and bone mineral density following parathyroidectomy. Bone 25: 237-244
28. Dalen N, Hjern B 1974 Bone mineral content in patients with primary hyperparathyroidism without radiological evidence of skeletal changes. Acta Endocrinol (Copenh) 75:297-304
29. Almqvist EG, Becker C, Bondeson AG, Bondeson L, Svensson J 2004 Early parathyroidectomy increases bone mineral density in patients with mild primary hyperparathyroidism: a prospective and randomized study. Surgery 136:1281-1288
30. Rao DS, Phillips ER, Divine GW, Talpos GB 2004 Randomized controlled clinical trial of surgery versus no surgery in patients with mild asymptomatic primary hyperparathyroidism. J Clin Endocrinol Metab 89:5415-5422
31. Ambrogini E, Cetani F, Cianferotti L, Vignali E, Banti C, Viccica G, Oppo A, Miccoli P, Berti P, Bilezikian JP, Pinchera A, Marcocci C 2007 Surgery or surveillance for mild asymptomatic primary hyperparathyroidism: a prospective, randomized clinical trial. J Clin Endocrinol Metab 92:3114-3121
32. Bollerslev J, Jansson S, Mollerup CL, Nordenstrom J, Lundgren E, Torring O, Varhaug JE, Baranowski M, Aanderud S, Franco C, Freyschuss B, Isaksen GA, Ueland T, Rosen T 2007 Medical observation, compared with parathyroidectomy, for asymptomatic primary hyperparathyroidism: a prospective, randomized trial. J Clin Endocrinol Metab 92:1687-1692
33. Bilezikian JP 2003 Bone strength in primary hyperparathyroidism. Osteoporos Int 14(Suppl 5):113-117
34. Ahlborg HG, Johnell O, Turner CH, Rannevik G, Karlsson MK 2003 Bone loss and bone size after menopause. N Engl J Med 349:327-334
35. Charopoulos I, Tournis S, Trovas G, Raptou P, Kaldrymides P, Skarandavos G, Katsalira K, Lyritis GP 2006 Effect of primary hyperparathyroidism on volumetric bone mineral density and bone geometry assessed by peripheral quantitative computed tomography in postmenopausal women. J Clin Endocrinol Metab 91:1748-1753
36. Roschger P, Dempster DW, Zhou H, Paschalis EP, Silverberg SJ, Shane E, Bilezikian JP, Klaushofer K 2007 New observations on bone quality in mild primary hyperparathyroidism as determined by quantitative backscattered electron imaging. J Bone Miner Res 22:717-723
37. Vestergaard P, Mollerup CL, Frokjaer VG, Christiansen P, Blichert-Toft M, Mosekilde L 2000 Cohort study of risk of fracture before and after surgery for primary hyperparathyroidism. BMJ 321:598-602
38. Khosla S, Melton 3rd LJ, Wermers RA, Crowson CS, O'Fallon W, Riggs B 1999 Primary hyperparathyroidism and the risk of fracture: a population-based study. J Bone Miner Res 14:1700-1707
39. Nilsson IL, Yin L, Lundgren E, Rastad J, Ekbom A 2002 Clinical presentation of primary hyperparathyroidism in Europe-nationwide cohort analysis on mortality from nonmalignant causes. J Bone Miner Res 17(Suppl 2):N68-N74
40. Wermers RA, Khosla S, Atkinson EJ, Grant CS, Hodgson SF, O'Fallon WM, Melton 3rd LJ 1998 Survival after the diagnosis of hyperparathyroidism: a population-based study. Am J Med 104:115-122