Application of molecular topology to the prediction of the antimalarial activity of a group of uracil-based acyclic and deoxyuridine compounds

International Journal of Pharmaceutics

Volumn 363, Issue 1-2, 2008, Pages 78-84

  García Domenech, Ramón ^a   López Peña, Wanda ^a   Sanchez Perdomo, Yessenia ^a   Sanders, José R ^a   Sierra Araujo, Mercedes M ^a   Zapata, Claudy ^a   Gálvez, Jorge ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Antimalarial activity; Linear discriminant analysis; Molecular topology; Multilinear regression analysis

Indexed keywords

ANTIMALARIAL AGENT; DEOXYURIDINE DERIVATIVE; URACIL;

ANTIMALARIAL ACTIVITY; ARTICLE; IC 50; LINEAR REGRESSION ANALYSIS; MATHEMATICAL MODEL; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; DEOXYURIDINE; DISCRIMINANT ANALYSIS; DRUG DESIGN; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PLASMODIUM FALCIPARUM; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REGRESSION ANALYSIS; TECHNOLOGY, PHARMACEUTICAL; URACIL; USER-COMPUTER INTERFACE;

EID: 51649094497     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.07.003     Document Type: Article

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