Biochemical evaluation of human DNA-lysine photoadduct treated with peroxynitrite

Toxicology Mechanisms and Methods

Volumn 18, Issue 7, 2008, Pages 589-595

  Ahmad, Rizwan ^a   Rasheed, Zafar ^a   Kaushal, Esha ^a   Singh, Divya ^a   Ahsan, Haseeb ^b  

^a Sardar Bhagwan Singh Post Gratudate Institute of Biomedical Sciences & Research   (India)

^b HAMDARD UNIVERSITY   (India)

Author keywords

Human DNA; Lysine; Peroxynitrite; Photoadduct

Indexed keywords

ARGININE; DNA; HISTONE; LYSINE; PEROXYNITRITE;

ABSORPTION; ARTICLE; CHROMATIN; CHROMATOGRAPHY; CONTROLLED STUDY; DNA ADDUCT; DNA CROSS LINKING; DNA HELIX; DNA STRAND BREAKAGE; DNA STRUCTURE; FLUORESCENCE; GEL FILTRATION; HUMAN; LIGHT ABSORPTION; NUCLEOSOME; PHOTOCHEMISTRY; PRIORITY JOURNAL; TEMPERATURE;

EID: 51649094077     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510802205676     Document Type: Article

References (22)

1. Ahsan, H., Abdi, S., and Ali, A. 2002. Recognition of DNA-arginine photoadduct by anti-DNA auto-antibodies in systemic lupus erythematosus. Ind. J. Med. Res. 115:201-211.
2. Ahsan, H., Ali, A., and Ali, R. 2003. Oxygen free radicals and systemic autoimmunity. Clin. Exp. Immunol. 131(3):398-404.
3. Arif, Z., and Ali, R. 1996. Nucleic acid-8-methoxypsoralen crosslinks bind monoclonal anti-Z-DNA antibody. Biochem. Mol. Biol. Int. 40(5):871-879.
4. Arjumand, S., Moinuddin, and Ali, A. 1997. Binding characteristics of SLE anti-DNA autoantibodies to modified DNA analogues. Biochem. Mol. Biol. Int. 43(3):643-653.
5. Dixit, K., Ahsan, H., and Ali, A. 2003. Polydeoxyribonucleotide C photoconjugated with lysine or arginine present unique epitopes for human anti-DNA autoantibodies. Hum. Immunol. 64(9):880-886.
6. Dixit, K., Moinuddin, and Ali, A. 2005. Immunological studies on peroxynitrite modified DNA. Life Sci. 77(21):2626-2642.
7. Epplen, J. E., and Lubjuhn, T. 1999. DNA Profiling and DNA Fingerprinting. Birhkhauser Verlag, Berlin.
8. Habib, S., Moinuddin, and Ali, R. 2006. Peroxynitrite modified DNA: a better antigen for systemic lupus erythematosus anti-DNA autoantibodies. Biotechnol. Appl. Biochem. 43(2):65-70.
9. Islam, N., and Ali, R. 1995. Formation of thymine-lysine and cytosine-lysine adducts in DNA-lysine photoconjugate. J. Photochem. Photobiol. 27:109-115.
10. Islam, N., and Ali, R. 1998. Immunological studies on DNA-lysine photoadduct. Biochem. Mol. Biol. Int. 45(3):453-464.
11. Miles, A. M., Bohle, D. S., Glassbrenner, P. A., Hansert, B., Wink, D. A., and Grisham, M. B. 1996. Modulation of superoxide-dependent oxidation and hydroxylation reactions by nitric oxide. J. Biol. Chem. 271(1):40-47.
12. Miller, S. A., Dykes, D. D., and Polesky, H. F. 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16(3):1215.
13. Ohshima, H., and Bartsch, H. 1994. Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. Mutat. Res. 305(2):253-264.
14. Ohshima, H. 2003. Genetic and epigenetic damage induced by reactive nitrogen species: implications in carcinogenesis. Toxicol. Lett. 140-141:99-104.
15. Pacher, P., Beckman, J. S., and Liaudet, L. 2007. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev. 87(1):315-424.
16. Pryor, W. A., and Squadrito, G. L. 1995. The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am. J. Physiol. 268(5pt1):L699-L722.
17. Szabo, C., and Ohshima, H. 1997. DNA damage induced by peroxynitrite: subsequent biological effects. Nitric Oxide 1(7):373-385.
18. Szabo, C., Ischiropoulos, H., and Radi, R. 2007. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat. Rev. Drug Discov. 6(8):662-680.
19. Szabo, C. 2003. Multiple pathways of peroxynitrite cytotoxicity. Toxicol. Lett. 140-141:105-112.
20. Tretyakova, N. Y., Burney, S., Pamir, B., Wishnok, J. S., Dedon, P. C., Wogan, G. N., and Tannenbaum, S. R. 2000. Peroxynitrite-induced DNA damage in the sup F gene: correlation with the mutational spectrum. Mutat. Res. 447(2):287-303.
21. Wiseman, H., and Halliwell, B. 1996. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem. J. 313(1):17-29.
22. Yermilov, V., Rubio, J., Becchi, M., Friesen, M. D., Pignatelli, B., and Ohshima, H. 1995. Formation of 8-nitroguanine by the reaction of guanine with peroxynitrite in vitro. Carcinogenesis 16(9):2045-2050.