A modified approach to predict dissolution and absorption of polydisperse powders

Pharmaceutical Research

Volumn 25, Issue 10, 2008, Pages 2309-2311

  Butcher, John C ^a   Garg, Sanjay ^a   Kim, Dawoomi ^a   Sharma, Puneet ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Absorption; Dissolution rate prediction; Particle size; Polydisperse powders; Solubility

Indexed keywords

ABSORPTION; ARTICLE; DISSOLUTION; PARTICLE SIZE; POLYDISPERSE POWDER; POWDER; PREDICTION; PRIORITY JOURNAL; SIMULATION; SOLUBILITY; TECHNIQUE; THERMODYNAMICS;

ABSORPTION; ADMINISTRATION, ORAL; CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; DIFFUSION; MODELS, CHEMICAL; PARTICLE SIZE; POWDERS; REPRODUCIBILITY OF RESULTS; SOFTWARE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL;

EID: 51649086857     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9630-3     Document Type: Article

References (8)

1. A. Lipinski F. Lombardo W. Dominy J. Feeney 2001 Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings Adv. Drug Deliv. Rev. 46 1-3 3 26
2. V. Varma S. Khandavilli Y. Ashokraj A. Jain A. Dhanikula A. Sood S. Thomas O. Pillai P. Sharma R. Gandhi S. Agrawal V. Nair R. Panchagnula 2004 Biopharmaceutic classification system: a scientific framework for pharmacokinetic optimization in drug research Curr. Drug Metab. 5 5 375 388
3. J. Hintz C. Johnson 1989 The effect of particle size distribution on dissolution rate and oral absorption Int. J. Pharm. 51 1 9 17
4. C. Johnson 2003 Dissolution and absorption modeling: model expansion to simulate the effects of precipitation, water absorption, longitudinally changing intestinal permeability, and controlled release on drug absorption Drug Dev. Ind. Pharm. 29 8 833 842
5. C. Johnson C. Swindell 1996 Guidance in the setting of drug particle size specifications to minimize variability in absorption Pharm. Res. 13 12 1795 1798
6. T. Lu E. Frisella C. Johnson 1993 Dissolution modelling: factors affecting the dissolution rates of polydisperse powders Pharm. Res. 10 9 1308 1314
7. P. Tinke K. Vanhoutte R. De Maesschalck S. Verheyen H. De Winter 2005 A new approach in the prediction of the dissolution behavior of suspended particles by means of their particle size distribution J. Pharm. Biomed. Anal. 39 5 900 907
8. B. Patravale A. Date M. Kulkarni 2004 Nanosuspensions: a promising drug delivery strategy J. Pharm. Pharmacol. 56 7 827 840