Fundamental chromatographic equations designed for columns packed with very fine particles and operated at very high pressures. Applications to the prediction of elution times and the column efficiencies

Journal of Chromatography A

Volumn 1206, Issue 2, 2008, Pages 113-122

  Gritti, Fabrice ^a,b   Guiochon, Georges ^a,b  

^a UNIVERSITY OF TENNESSEE   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

Acetonitrile mobile phase; C18 bonded silica; Heat effects; Longitudinal and radial temperature gradients; Mobile phase friction; Naphtho 2,3 a pyrene; VHPLC columns

Indexed keywords

ACETONITRILE MOBILE PHASE; C18-BONDED SILICA; HEAT EFFECTS; LONGITUDINAL AND RADIAL TEMPERATURE GRADIENTS; MOBILE PHASE FRICTION; NAPHTHO[2,3-A]PYRENE; VHPLC COLUMNS;

COLUMNS (STRUCTURAL);

ACETONITRILE; NAPHTHALENE DERIVATIVE; NAPHTHO[2,3 A]PYRENE; PYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; CHROMATOGRAPHIC COLUMN; CHROMATOGRAPHY; CIRCULATING WATER HEAT EXCHANGER; DEVICE; ELUTION; ELUTION TIME; EQUIPMENT DESIGN; FLOW RATE; FRICTION; HEAT EXCHANGE; HEAT TRANSFER; ISOTHERM; MATHEMATICAL ANALYSIS; MEASUREMENT; PARTICLE SIZE; PREDICTION; PRESSURE; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY; THERMODYNAMICS; TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTRUMENTATION; METHODOLOGY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; PARTICLE SIZE; PRESSURE;

EID: 51549120113     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.07.084     Document Type: Article

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