Evolution of the human brain, chorionic gonadotropin and hemochorial implantation of the placenta: Insights into origins of pregnancy failures, preeclampsia and choriocarcinoma

Journal of Reproductive Medicine for the Obstetrician and Gynecologist

Volumn 53, Issue 8, 2008, Pages 549-557

  Cole, Laurence A ^a   Khanlian, Sarah A ^b   Kohorn, Ernest I ^b  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Brain; Evolution; Gestational trophoblastic disease; Hemochorial implantation; Hyperglycosylated human chorionic gonadotropin

Indexed keywords

CHORIONIC GONADOTROPIN;

BRAIN DEVELOPMENT; CELL GROWTH; CELL INVASION; CHORIOCARCINOMA; CONFERENCE PAPER; CYTOTROPHOBLAST; HUMAN; IMPLANTATION; NONHUMAN; PLACENTA; PREECLAMPSIA; PREGNANCY OUTCOME; PRIORITY JOURNAL; REPRODUCTION; TROPHOBLASTIC TUMOR;

ANIMALS; BRAIN; CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; EVOLUTION; FEMALE; GESTATIONAL TROPHOBLASTIC NEOPLASMS; HUMANS; PLACENTA; PLACENTATION; PRE-ECLAMPSIA; PREGNANCY; PRIMATES;

EID: 51549117870     PISSN: 00247758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (58)

1. Gibbons A: Solving the brain's energy crisis. Science 1998; 280:1345-1347
2. Kliman HJ: Uteroplacental blood flow: The story of decidualization, menstruation, and trophoblast invasion. Am J Pathol 2000;157:1759-1768
3. Robillard PY, Hulsey TC, Dekker GA, et al: Preeclampsia and human reproduction: An essay of a long term reflection. J Reprod Immunol 2003;59:93-100
4. Martin RD: Scaling of the mammalian barrier: The maternal energy hypothesis. News Physiol Sci 1996;4:149-154
5. Cunnane SC, Herbige LS, Crawford MA: The importance of energy and nutrient supply in human brain evolution. Nutr Health 1993;9:19-35
6. Robillard PY, Chaline J, Chaouat G, et al: Preeclampsia/ eclampsia and the evolution of the human brain. Current Anthropol 2003;44:130-135
7. Jauniaux E, Poston L, Burton GJ: Placental-related diseases of pregnancy: Involvement of oxidative stress and implications in human evolution. Hum Reprod Update 2006;12:747-755
8. Martin RD: Human reproduction: A comparative background for medical hypotheses. J Reprod Immunol 2003;59:111-135
9. Martin RD: Relative brain size and basal metabolic rate in terrestrial vertebrates. Nature 1981;293:57-60
10. Pijnenborg R: The placental bed. Hypertens Pregn 1996;15:7-23
11. Cole LA, Dai D, Butler SA, et al: Gestational trophoblastic diseases: I. Pathophysiology of hyperglycosylated hCG-regulated neoplasia. Gynecol Oncol 2006;102:144-149
12. Cole LA, Khanlian SA, Riley JM, et al: Hyperglycosylated hCG in gestational implantation and in choriocarcinoma and testicular germ cell malignancy tumorigenesis. J Reprod Med 2006;51:919-915
13. Hamade AL, Nakabayashi K, Sato A, et al: Transfection of antisense chorionic gonadotropin β gene into choriocarcinoma cells suppresses the cell proliferation and induces apoptosis. J Clin Endocrinol Metab 2005;90:4873-4879
14. Jauniaux E, Gulbis B, Burton GJ: Placenta: The human first trimester gestational sac limits rather than facilitates oxygen transfer to the foetus: A review. Trophobl Res (suppl) 2003; 24:S86-S93
15. Burton GJ: Early placental development. Placenta 2006;27:A2
16. Shi QJ, Lei ZM, Rao CV, et al: Novel role of human chorionic gonadotropin in differentiation of human cytotrophoblasts. Endocrinology 1993;132:1387-1395
17. Lei ZM, Reshef E, Rao CV: The expression of human chorionic gonadotropin/luteinizing hormone receptors in human endometrial and myometrial blood vessels. J Clin Endocrinol Metab 1992;75:651-659
18. Herr F, Baal N, Reisinger K, et al: hCG in the regulation of placental angiogenesis: Results of an in vitro study. Placenta (Suppl A) 2007;28:S85-S93
19. Zygmunt M, Herr F, Munstedt K, et al: Angiogenesis and vasculogenesis in pregnancy. Euro J Obstet Gynecol Reprod Biol (Suppl 1) 2003;110:S10-S18
20. Zygmunt M, Herr F, Keller-Schoenwetter S, et al: Characterization of human chorionic gonadotropin as a novel angiogenic factor. J Clin Endocrinol Metab 2002;87:5290-5296
21. Toth P, Lukacs H, Gimes G, et al: Clinical importance of vascular LH/hCG receptors: A review. Reprod Biol 2001;1:5-11
22. Rao CV, Alsip NL: Use of the rat model to study hCG/LH effects on uterine blood flow. Semin Reprod Med 2001;19:75-85
23. Burton GJ: Placental oxidative stress: From miscarriage to preeclampsia. J Soc Gyn Invest 2004;11:342-352
24. Carver J, Martin K, Spyropoulou I, et al: An in-vitro model for stromal invasion during implantation of the human blastocyst. Hum Reprod 2003;18:283-290
25. Jauniaux E, Hempstock J, Greenwold N, et al: Trophoblast oxidative stress in relation to temporal and regional differences in maternal placental blood flow in normal and abnormal early pregnancies. Am J Path 2003;162:115-125
26. Pijnenborg R, Vercruysse L, Hanssens M: The uterine spiral arteries in human pregnancy: Facts and controversies. Placenta 2006;27:939-958
27. Jauniaux E, Watson AL, Hempstock J, et al: Onset of maternal arterial blood bloodflow and placental oxidative stress: A possible factor in human early pregnancy failure. Am J Pathol 2000;157:2111-2122
28. Rodesch F, Simon P, Donner C, et al: Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstet Gynecol 1992;80:283-285
29. Burton GJ, Jauniaux E, Watson AL: Maternal arterial connections to the placental intervillous space during the first trimester of pregnancy: The Boyd collection revisited. Am J Obstet Gynecol 1999;181:718-724
30. Elliott MM, Kardana A, Lustbader JW, et al: Carbohydrate and peptide structure of the α- and β-subunits of human chorionic gonadotropin from normal and aberrant pregnancy and choriocarcinoma. Endocrine 1997;7:15-32
31. Cole LA: The O-linked oligosaccharide structures are strikingly different on pregnancy and choriocarcinoma hCG. J Clin Endocrinol Metab 1987;65:811-813
32. Amano J, Nishimura R, Mochizuki M, et al: Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women. J Biol Chem 1988;263:1157-1165
33. Valmu L, Alfthan H, Hotakainen K, et al: Site-specific glycan analysis of human chorionic gonadotropin b subunit from malignancies and pregnancy by liquid chromatography-electrospray mass spectrometry. Glycobiology 2006;16:1207-1218
34. Kobata A, Takeuchi M: Structure, pathology and function of the N-linked sugar chains of human chorionic gonadotropin. Biochim Biophys Acta 1999;1455:315-326
35. Birken S, Krichevsky A, O'Connor J, et al: Development and characterization of antibodies to a nicked and hyperglycosylated form of hCG from a choriocarcinoma patient. Endocrine 1999;10:137-144
36. Cole LA, Khanlian SA, Sutton JM, et al: Hyperglycosylated hCG (invasive trophoblast antigen, ITA): A key antigen for early pregnancy detection. Clin Biochem 2003;36:647-655
37. O'Connor JF, Ellish N, Kakuma T, et al: Differential urinary gonadotrophin profiles in early pregnancy and early pregnancy loss. Prenat Diagn 1998;18:1232-1240
38. Sutton-Riley JM, Khanlian SA, Byrn FW, et al: A single serum test for measuring pregnancy outcome with high predictive value. Clin Biochem 2006;39:682-687
39. Sasaki Y, Ladner DG, Khanlian SA, et al: Hyperglycosylated hCG and the source of pregnancy failures. Fertil Steril 2008 (in press)
40. Cole LA: O-glycosylation of proteins in the normal and neoplastic trophoblast. Trophobl Res 1987;2:139-148
41. Kovalevskaya G, Genbacev O, Fisher SJ, et al: Trophoblast origin of hCG isoforms: Cytotrophoblasts are the primary source of choriocarcinoma-like hCG. Mol Cell Endocrinol 2002;194:147-155
42. Lei ZM, Taylor DD, Gercel-Taylor C, et al: Human chorionic gonadotropin promotes tumorigenesis of choriocarcinoma J Ar cells. Trophobl Res 1999;13:147-159
43. Handshuh K, Guibourdenche J, Tsatsaris V, et al: Human chorionic gonadotropin produced by the invasive trophoblast but not the villous trophoblast promotes cell invasion and is down-regulated by peroxisome proliferator-activated receptor-α. Endocrinol 2007;148:5011-5019
44. Fiddes JC, Goodman HM: The cDNA for the β-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3′-untranslated region. Nature 1980;286:684-687
45. Maston GA, Ruvolo M: Chorionic gonadotropin has a recent origin within primates and an evolutionary history of selection. Mol Biol Evol 2002;19:320-334
46. Nisula BC, Wehmann RE: Distribution, metabolism, and excretion of human chorionic gonadotropin and its subunits in man. In Chorionic Gonadotropin. Edited by SJ Segal. New York, Plenum Press, 1980, pp 199-212
47. Diebel ND, Bogdsanove EM: Analysis of luteinizing hormone and follicle-stimulating hormone release kinetics during a dynamic secretory event, the postpartum preovulatory surge in the rat, based on quantitative changes in stored and circulating luteinizing hormone and follicle-stimulating hormone and metabolic clearance data for these hormones. Endocrinology 1978;103:665-673
48. Crawford RJ, Tregear GW, Niall HD: The nucleotide sequence of baboon chorionic gonadotropin β-subunit genes have diverged from the human. Gene 1986;46:161-169
49. Bambra CS: Purification and properties of baboon chorionic gonadotrophin. J Reprod Fertil 1987;19:421-430
50. Cole LA: Hyperglycosylated hCG. Placenta 2007;28:977-986
51. Kovalevskaya G, Birken S, Kakuma T, et al: Differential expression of human chorionic gonadotropin (hCG) glycosylation isoforms in failing and continuing pregnancies: Preliminary characterization of the hyperglycosylated hCG epitope. J Endocrinol 2002;172:497-506
52. Norwitz ER, Schust DJ, Fisher SJ: Implantation and the survival of early pregnancy. N Engl J Med 2001;345:1400-1408
53. Wilcox AJ, Baird DD, Weinberg CR: Time of implantation of the conceptus and loss of pregnancy. N Engl J Med 1999;340:1796-1799
54. Bahado-Singh RO, Oz AU, Kingston JM, et al: The role of hyperglycosylated hCG in trophoblast invasion and the prediction of subsequent preeclampsia. Prenat Diagn 2002;22:478-483
55. Wilmut I, Sales DL, Ashworth CJ: Maternal and embryonic factors associated with prenatal loss in mammals. J Reprod Fertil 1986;76:851-864
56. Bebyser INJ, Soma H, Zwart P: Partial hydatidiform mole in a pregnant chimpanzee. Zoo Biol 2005;12:299-305
57. Vrana KE, Hipp JD, Goss AM, et al: Nonhuman primate parthenogenetic stem cells. Proc Natl Acad Sci (Suppl 1) 2003;100:11911-11916
58. Cole LA, Butler SA, Khanlian SA, et al: Gestational trophoblastic diseases: II. Hyperglycosylated hCG as a reliable marker of active neoplasia. Gynecol Oncol 2006;102:150-158