A Role for galectin-3 in renal tissue damage triggered by ischemia and reperfusion injury

Transplant International

Volumn 21, Issue 10, 2008, Pages 999-1007

  Fernandes Bertocchi, Ana Paula ^b   Campanhole, Gabriela ^b   Wang, Pamella Huey Mei ^b   Gonçalves, Giselle Martins ^b   Damião, Márcio José ^b   Cenedeze, Marcos Antônio ^b   Beraldo, Felipe Caetano ^c   De Paula Antunes Teixeira, Vicente ^d   Dos Reis, Marlene Antônia ^d   Mazzali, Marilda ^c   Pacheco Silva, Alvaro ^b   Câmara, Niels Olsen Saraiva ^a,b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

^d Universidade Federal de Uberaba   (Brazil)

Author keywords

Galectin 3; IL 1 ; IL 6; Ischemia and reperfusion injury; MCP 1

Indexed keywords

GALECTIN 3; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE;

ACUTE KIDNEY TUBULE NECROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE RELEASE; FLOW CYTOMETRY; INFLAMMATION; ISCHEMIA; KIDNEY INJURY; KIDNEY PARENCHYMA; KNOCKOUT MOUSE; MACROPHAGE; MALE; MORPHOMETRICS; MORTALITY; MOUSE; NONHUMAN; OCCLUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; TISSUE REGENERATION; UREA BLOOD LEVEL; WILD TYPE;

ANIMALS; AUTOANTIGENS; BIOLOGICAL MARKERS; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; DNA; FLOW CYTOMETRY; FOLLOW-UP STUDIES; GALECTIN 3; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; INTERLEUKIN-6; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY;

EID: 51549116683     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2008.00705.x     Document Type: Article

References (47)

1. Krzeslak A, Lipinska A. Galectin-3 as a multifunctional protein. Cell Mol Biol Lett 2004 9 : 305.
2. Hsu DK, Yang RY, Pan Z, et al. Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses. Am J Pathol 2000 156 : 1073.
3. Colnot C, Ripoche MA, Milon G, Montagutelli X, Crocker PR, Poirier F. Maintenance of granulocyte numbers during acute peritonitis is defective in galectin-3-null mutant mice. Immunology 1998 94 : 290.
4. Jeng KC, Frigeri LG, Liu FT. An endogenous lectin, galectin-3 (epsilon BP/Mac-2), potentiates IL-1 production by human monocytes. Immunol Lett 1994 42 : 113.
5. Chen HY, Sharma BB, Yu L, et al. Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression. J Immunol 2006 15 : 177.
6. Joo HG, Goedegebuure PS, Sadanaga N, Nagoshi M, von Bernstorff W, Eberlein TJ. Expression and function of galectin-3, a beta-galactoside-binding protein in activated T lymphocytes. J Leukoc Biol 2001 69 : 555.
7. Bonventre JV, Zuk A. Ischemic acute renal failure: an inflammatory disease? Kidney Int 2004 66 : 480.
8. Friedewald JJ, Rabb H. Inflammatory cells in ischemic acute renal failure. Kidney Int 2004 66 : 486.
9. Molitoris BA, Sutton TA. Endothelial injury and dysfunction: role in the extension phase of acute renal failure. Kidney Int 2004 66 : 496.
10. Rabb H, Daniels F, O'Donnell M, et al. Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice. Am J Physiol Renal Physiol 2000 279 : F525.
11. Burne MJ, Daniels F, El Ghandour A, et al. Identification of the CD4(+) T cell as a major pathogenic factor in ischemic acute renal failure. J Clin Invest 2001 108 : 1283.
12. Pittock ST, Norby SM, Grande JP, et al. MCP-1 is up-regulated in unstressed and stressed HO-1 knockout mice: pathophysiologic correlates. Kidney Int 2005 68 : 611.
13. Marques VP, Goncalves GM, Feitoza CQ, et al. Influence of TH1/TH2 switched immune response on renal ischemia-reperfusion injury. Nephron Exp Nephrol 2006 104 : e48.
14. Kanakiriya SK, Croatt AJ, Haggard JJ, et al. Heme: a novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms. Am J Physiol Renal Physiol 2003 284 : F546.
15. Nishiyama J, Kobayashi S, Ishida A, et al. Up-regulation of galectin-3 in acute renal failure of the rat. Am J Pathol 2000 157 : 815.
16. Kelly KJ, Bonventre JV. Ischemia/reperfusion in transplantation. In : Tilney NL, Strom TB, Paul LC, eds. Transplantation Biology. Philadelphia, PA : Lippincott-Raven Publishers, 1996 : 257 274.
17. Hasui M, Hirabayashi Y, Kobayashi Y. Simultaneous measurement by flow cytometry of phagocytosis and hydrogen peroxide production of neutrophils in whole blood. J Immunol Methods 1989 117 : 53.
18. Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med 1996 334 : 1448.
19. Kieran NE, Rabb H. Immune responses in kidney preservation and reperfusion injury. J Investig Med 2004 52 : 310.
20. Rabb H. The T cell as a bridge between innate and adaptive immune systems: implications for the kidney. Kidney Int 2002 61 : 1935.
21. Docherty NG, Lopez-Novoa JM, Arevalo M, et al. Endoglin regulates renal ischemia-reperfusion injury. Nephrol Dial Transplant 2006 21 : 2106 19.
22. Jo SK, Sung SA, Cho WY, Go KJ, Kim HK. Macrophages contribute to the initiation of ischaemic acute renal failure in rats. Nephrol Dial Transplant 2006 21 : 1231.
23. Ysebaert DK, De Greef KE, De Beuf A, et al. T cells as mediators in renal ischemia/reperfusion injury. Kidney Int 2004 66 : 491.
24. Domanski L, Pawlik A, Safranow K, et al. Purine and cytokine concentrations in the renal vein of the allograft during reperfusion. Transplant Proc 2007 39 : 1319.
25. Vinuesa E, Hotter G, Jung M, Herrero-Fresneda I, Torras J, Sola A. Macrophage involvement in the kidney repair phase after ischemia/reperfusion injury. J Pathol 2008 214 : 104 13.
26. Furuichi K, Wada T, Iwata Y, et al. Interleukin-1-dependent sequential chemokine expression and inflammatory cell infiltration in ischemia-reperfusion injury. Crit Care Med 2006 34 : 2447 55.
27. Day YJ, Huang L, Ye H, Linden J, Okusa MD. Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. Am J Physiol Renal Physiol 2005 288 : F722 31.
28. Furuichi K, Wada T, Iwata Y, et al. CCR2 signaling contributes to ischemia-reperfusion injury in kidney. J Am Soc Nephrol 2003 14 : 2503 15.
29. Sung FL, Zhu TY, Au-Yeung KK, Siow YL, O K. Enhanced MCP-1 expression during ischemia/reperfusion injury is mediated by oxidative stress and NF-kappaB. Kidney Int 2002 62 : 1160 70.
30. Bichara M, Attmane-Elakeb A, Brown D, et al. Exploring the role of galectin 3 in kidney function: a genetic approach. Glycobiology 2006 16 : 36.
31. Simon LS. Role and regulation of cyclooxygenase-2 during inflammation. Am J Med 1999 106 : 37S.
32. Bolli R. The late phase of preconditioning. Circ Res 2000 87 : 972 983.
33. Yamaoka A, Kuwabara I, Frigeri LG, Liu FT. A human lectin, galectin-3 (epsilon bp/Mac-2), stimulates superoxide production by neutrophils. J Immunol 1995 154 : 3479.
34. Liu FT, Hsu DK, Zuberi RI, Kuwabara I, Chi EY, Henderson WR, Jr. Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages. Am J Pathol 1995 147 : 1016.
35. Almkvist J, Karlsson A. Galectins as inflammatory mediators. Glycoconj J 2004 19 : 575.
36. Almkvist J, Faldt J, Dahlgren C, Leffler H, Karlsson A. Lipopolysaccharide-induced gelatinase granule mobilization primes neutrophils for activation by galectin-3 and formylmethionyl-Leu-Phe. Infect Immun 2001 69 : 832.
37. Matarrese P, Tinari N, Semeraro ML, Natoli C, Iacobelli S, Malorni W. Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis. FEBS Lett 2000 473 : 311.
38. Gil CD, Cooper D, Rosignoli G, Perretti M, Oliani SM. Inflammation-induced modulation of cellular galectin-1 and -3 expression in a model of rat peritonitis. Inflamm Res 2006 55 : 99.
39. Dabelic S, Supraha S, Dumic J. Galectin-3 in macrophage-like cells exposed to immunomodulatory drugs. Biochim Biophys Acta 2006 1760 : 701.
40. Sharma UC, Pokharel S, van Brakel TJ, et al. Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation 2004 110 : 3121.
41. Zuberi RI, Hsu DK, Kalayci O, et al. Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol 2004 165 : 2045.
42. Takada M, Nadeau KC, Shaw GD, Marquette KA, Tilney NL. The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand. J Clin Invest 1997 99 : 2682.
43. Laskowski I, Pratschke J, Wilhelm MJ, Gasser M, Tilney NL. Molecular and cellular events associated with ischemia/reperfusion injury. Ann Transplant 2000 5 : 29.
44. Azuma H, Nadeau K, Takada M, Mackenzie HS, Tilney NL. Cellular and molecular predictors of chronic renal dysfunction after initial ischemia/reperfusion injury of a single kidney. Transplantation 1997 64 : 190.
45. Yokota N, Burne-Taney M, Racusen L, Rabb H. Contrasting roles for STAT4 and STAT6 signal transduction pathways in murine renal ischemia-reperfusion injury. Am J Physiol Renal Physiol 2003 285 : F319.
46. Saada A, Reichert F, Rotshenker S. Granulocyte macrophage colony stimulating factor produced in lesioned peripheral nerves induces the up-regulation of cell surface expression of MAC-2 by macrophages and Schwann cells. J Cell Biol 1996 133 : 159.
47. Karlsen AE, Storling ZM, Sparre T, et al. Immune-mediated beta-cell destruction in vitro and in vivo-A pivotal role for galectin-3. Biochem Biophys Res Commun 2006 344 : 406.