Synthesis of 6′-branched locked nucleic acid by a radical TEMPO-scavanged stereoselective mercury cyclization

Journal of Organic Chemistry

Volumn 73, Issue 17, 2008, Pages 6891-6894

  Enderlin, Gerald ^a   Nielsen, Poul ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; ARSENIC COMPOUNDS; AUDIO FREQUENCY AMPLIFIERS; CHEMICAL REACTIONS; CYCLIZATION; LOW NOISE AMPLIFIERS; MERCURY (METAL); METHANOL; MONOMERS; NITROGEN COMPOUNDS; NUCLEIC ACIDS;

HYDROXY METHYL; LOCKED NUCLEIC ACID; STEREO-SELECTIVE;

DIFFERENCE EQUATIONS;

2,2,6,6 TETRAMETHYL 1 PIPERIDINYLOXYL; 7 BENZYLOXY 1 BENZYLOXYMETHYL 3 (THYMIN 1 YL) 6 HYDROXYMETHYL 2,5 DIOXABICYCLO[2.2.1]HEPTANE; 7 BENZYLOXY 1 BENZYLOXYMETHYL 6 (2,2,6,6 TETRAMETHYLPIPERIDIN 1 YL)OXYMETHYL 3 (THYMIN 1 YL) 2,5 DIOXABICYCLO[2.2.1]HEPTANE; 7 BENZYLOXY 1 BENZYLOXYMETHYL 6 BROMOMERCURIMETHYL 3 (THYMIN1 YL) 2,5 DIOXABICYCLO[2.2.1]HEPTANE; AZIDE; LOCKED NUCLEIC ACID; MERCURY; METHYL GROUP; MONOMER; NUCLEOSIDE; SCAVENGER; THYMIDINE; TRIAZOLE; UNCLASSIFIED DRUG; AMINE OXIDE; DRUG DERIVATIVE; OLIGONUCLEOTIDE; TEMPO; TRIAZOLE DERIVATIVE;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CYCLIZATION; CYCLOADDITION; EPOXIDATION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; CHEMICAL MODEL; CHEMISTRY; STEREOISOMERISM;

AZIDES; CYCLIC N-OXIDES; CYCLIZATION; FREE RADICAL SCAVENGERS; MERCURY; MODELS, CHEMICAL; OLIGONUCLEOTIDES; STEREOISOMERISM; THYMIDINE; TRIAZOLES;

EID: 51549108504     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo801081t     Document Type: Article

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