Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by high-performance liquid chromatography-electrospray ionization mass spectrometric method

Phytomedicine

Volumn 15, Issue 10, 2008, Pages 844-850

  Zhang, W ^a   Sheng, Y X ^a   Zhang, J L ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Gastrodia elata Bl; Gastrodin; HPLC MS; p Hydroxybenzylalcohol; Pharmacokinetics

Indexed keywords

2 FUROIC ACID; 4 HYDROXYBENZYL ALCOHOL; BENZYL ALCOHOL DERIVATIVE; GASTRODIA ELATA EXTRACT; GASTRODIN; METHANOL; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; GASTRODIA ELATA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLASMA CLEARANCE; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; RAT; REPRODUCIBILITY; RHIZOME; STANDARD; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; BENZYL ALCOHOLS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GASTRODIA; GLUCOSIDES; PLANT EXTRACTS; RATS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

GASTRODIA ELATA; RATTUS;

EID: 51549088172     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2008.02.012     Document Type: Article

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