Chitosan and enteric polymer based once daily sustained release tablets of aceclofenac: In Vitro and In Vivo studies

AAPS PharmSciTech

Volumn 9, Issue 2, 2008, Pages 651-659

  Mutalik, Srinivas ^a,c   Manoj, Krishnan ^a   Reddy, Meka Sreenivasa ^a   Kushtagi, Pralhad ^b   Usha, Achutha Nayak ^a   Anju, Parambil ^a   Ranjith, Averineni Kumar ^a   Udupa, Nayanabhirama ^a  

^a MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

^b KASTURBA MEDICAL COLLEGE   (India)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Aceclofenac; Chitosan; Matrix tablet; Pharmacokinetics; Sustained release

Indexed keywords

ACECLOFENAC; CELLACEFATE; CHITOSAN; DODECYL SULFATE SODIUM; EXCIPIENT; HIFENAC; HYDROCHLORIC ACID; HYDROXYPROPYLMETHYLCELLULOSE PHTHALATE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; POVIDONE; TALC; UNCLASSIFIED DRUG; CELLULOSE; DICLOFENAC; DRUG CARRIER; DRUG DERIVATIVE; METHYLCELLULOSE; NONSTEROID ANTIINFLAMMATORY AGENT;

AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BLOOD LEVEL; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; ENTERIC COATED TABLET; EXCIPIENT COMPATIBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MAXIMUM PLASMA CONCENTRATION; MORPHOLOGY; PHYSICAL CHEMISTRY; PREFORMULATION; RANDOMIZED CONTROLLED TRIAL; SCANNING ELECTRON MICROSCOPY; SINGLE BLIND PROCEDURE; SUSTAINED RELEASE FORMULATION; TABLET COMPRESSION; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION; VOLUNTEER; CHEMISTRY; DELAYED RELEASE FORMULATION; DOUBLE BLIND PROCEDURE; DRUG ADMINISTRATION; DRUG FORMULATION; INFRARED SPECTROPHOTOMETRY; METHODOLOGY; ORAL DRUG ADMINISTRATION; PH; PHARMACEUTICS; PHARMACOKINETICS; SOLUBILITY; SURFACE PROPERTY;

ADMINISTRATION, ORAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALORIMETRY, DIFFERENTIAL SCANNING; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; CROSS-OVER STUDIES; DELAYED-ACTION PREPARATIONS; DICLOFENAC; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; HUMANS; HYDROGEN-ION CONCENTRATION; METHYLCELLULOSE; MICROSCOPY, ELECTRON, SCANNING; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED; SURFACE PROPERTIES; TABLETS, ENTERIC-COATED; TECHNOLOGY, PHARMACEUTICAL; THERAPEUTIC EQUIVALENCY;

EID: 51449111668     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-008-9075-3     Document Type: Article

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