메뉴 건너뛰기




Volumn 13, Issue 17-18, 2008, Pages 771-777

Addressing informatics challenges in Translational Research with workflow technology

Author keywords

[No Author keywords available]

Indexed keywords

COMMERCIAL PHENOMENA; DATA ANALYSIS; DATA BASE; HUMAN; INFORMATION SCIENCE; INTERNET; MEDICAL RESEARCH; ORGANIZATION; PATIENT CARE; REVIEW; SCIENCE; TECHNOLOGY;

EID: 51449096433     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2008.06.005     Document Type: Review
Times cited : (12)

References (27)
  • 1
    • 51449100816 scopus 로고    scopus 로고
    • Billion dollar pills. The Economist January 25th 2007
    • Billion dollar pills. The Economist January 25th 2007
  • 2
    • 0141642224 scopus 로고    scopus 로고
    • The NIH Roadmap
    • Zerhouni E. The NIH Roadmap. Science 302 (2003) 63-72
    • (2003) Science , vol.302 , pp. 63-72
    • Zerhouni, E.1
  • 3
    • 33747804614 scopus 로고    scopus 로고
    • Translational Research in the pharmaceutical industry: from bench to bedside
    • O'Connell D., and Roblin D. Translational Research in the pharmaceutical industry: from bench to bedside. Drug Discov. Today 11 (2006) 833-838
    • (2006) Drug Discov. Today , vol.11 , pp. 833-838
    • O'Connell, D.1    Roblin, D.2
  • 4
    • 34247387591 scopus 로고    scopus 로고
    • Translational Research in the pharmaceutical industry: from theory to reality
    • Sultana S.R., Roblin D., and O'Connell D. Translational Research in the pharmaceutical industry: from theory to reality. Drug Discov. Today 12 (2007) 419-425
    • (2007) Drug Discov. Today , vol.12 , pp. 419-425
    • Sultana, S.R.1    Roblin, D.2    O'Connell, D.3
  • 5
    • 51449083820 scopus 로고    scopus 로고
    • Gilbert, J. et al. (2003) Rebuilding big pharma's business model. In vivo: the Business and Medicine Report. (vol. 21)
    • Gilbert, J. et al. (2003) Rebuilding big pharma's business model. In vivo: the Business and Medicine Report. (vol. 21)
  • 6
    • 10244255212 scopus 로고    scopus 로고
    • Taverna: a tool for the composition and enactment of bioinformatics workflows
    • Oinn T., et al. Taverna: a tool for the composition and enactment of bioinformatics workflows. Bioinformatics 20 (2004) 3045-3054
    • (2004) Bioinformatics , vol.20 , pp. 3045-3054
    • Oinn, T.1
  • 7
    • 34547136685 scopus 로고    scopus 로고
    • Discovering multiple transcripts of human hepatocytes using massively parallel signature sequencing (MPSS)
    • Huang J., et al. Discovering multiple transcripts of human hepatocytes using massively parallel signature sequencing (MPSS). BMC Genomics 8 (2007) 207
    • (2007) BMC Genomics , vol.8 , pp. 207
    • Huang, J.1
  • 8
    • 54949084597 scopus 로고    scopus 로고
    • Systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle
    • 10.1371/journal.pone.0000097
    • Laaksonen R.A. Systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle. PLoS One (2006). http://www.plosone.org 10.1371/journal.pone.0000097
    • (2006) PLoS One
    • Laaksonen, R.A.1
  • 9
    • 33646264570 scopus 로고    scopus 로고
    • Loss of TSLC1 causes male infertility due to a defect at the spermatic stage of spermatogenesis
    • van der Weyden L., et al. Loss of TSLC1 causes male infertility due to a defect at the spermatic stage of spermatogenesis. Mol. Cell Biol. 26 (2006) 3595-3609
    • (2006) Mol. Cell Biol. , vol.26 , pp. 3595-3609
    • van der Weyden, L.1
  • 10
    • 37549047172 scopus 로고    scopus 로고
    • Effects of iron loading on muscle: genome-wide mRNA expression profiling in the mouse
    • Rodriguez A., et al. Effects of iron loading on muscle: genome-wide mRNA expression profiling in the mouse. BMC Genomics 8 (2007) 379
    • (2007) BMC Genomics , vol.8 , pp. 379
    • Rodriguez, A.1
  • 11
    • 33748956663 scopus 로고    scopus 로고
    • Gene expression study in the juvenile mouse testis: identification of stage-specific molecular pathways during spermatogenesis
    • Clemente E.J., et al. Gene expression study in the juvenile mouse testis: identification of stage-specific molecular pathways during spermatogenesis. Mamm. Genome 17 (2006) 956-975
    • (2006) Mamm. Genome , vol.17 , pp. 956-975
    • Clemente, E.J.1
  • 12
    • 33644875860 scopus 로고    scopus 로고
    • Bridging the divide: the need for translational informatics
    • Online publication date: 1 January 2006
    • Gaughan A. Bridging the divide: the need for translational informatics. Pharmacogenomics 7 (2006) 117-122 Online publication date: 1 January 2006
    • (2006) Pharmacogenomics , vol.7 , pp. 117-122
    • Gaughan, A.1
  • 13
    • 18144411357 scopus 로고    scopus 로고
    • Translation research: from accurate diagnosis to appropriate treatment
    • Webb C.P., and Pass H.I. Translation research: from accurate diagnosis to appropriate treatment. J. Transl. Med. 2 (2004) 35
    • (2004) J. Transl. Med. , vol.2 , pp. 35
    • Webb, C.P.1    Pass, H.I.2
  • 14
    • 0038344487 scopus 로고    scopus 로고
    • Commercial biobanks and genetic research: ethical and legal issues
    • Anderlik M. Commercial biobanks and genetic research: ethical and legal issues. Am. J. Pharmacogenomics 3 (2003) 203-215
    • (2003) Am. J. Pharmacogenomics , vol.3 , pp. 203-215
    • Anderlik, M.1
  • 15
    • 20444445386 scopus 로고    scopus 로고
    • Web services in the life sciences
    • Curcin V., et al. Web services in the life sciences. Drug Discov. Today 10 (2005) 865-871
    • (2005) Drug Discov. Today , vol.10 , pp. 865-871
    • Curcin, V.1
  • 16
    • 34249860439 scopus 로고    scopus 로고
    • Advancing translational research with the semantic web
    • Ruttenberg, et al. Advancing translational research with the semantic web. BMC Bioinformatics 9 Suppl. 3 (2007)
    • (2007) BMC Bioinformatics , vol.9 , Issue.SUPPL. 3
    • Ruttenberg1
  • 17
    • 51449111925 scopus 로고    scopus 로고
    • An integrated framework for multiple myeloma research
    • Boston, MA, United States, April 28-30th
    • Quackenbush J. An integrated framework for multiple myeloma research. Proceedings of Bio-IT World Conference. Boston, MA, United States, April 28-30th (2008)
    • (2008) Proceedings of Bio-IT World Conference
    • Quackenbush, J.1
  • 18
    • 51449118862 scopus 로고    scopus 로고
    • InforSense Signs Dana-Farber as Latest Partner for Translational Research Platform
    • InforSense Signs Dana-Farber as Latest Partner for Translational Research Platform. Bioinformatics (2008)
    • (2008) Bioinformatics
  • 19
    • 33751329250 scopus 로고    scopus 로고
    • Global variation in copy number in the human genome
    • Redon R., et al. Global variation in copy number in the human genome. Nature 23 (2006) 444-454
    • (2006) Nature , vol.23 , pp. 444-454
    • Redon, R.1
  • 20
    • 0012781123 scopus 로고
    • The Hardy-Weinberg law
    • Stern C. The Hardy-Weinberg law. Science 97 (1943) 137-138
    • (1943) Science , vol.97 , pp. 137-138
    • Stern, C.1
  • 21
    • 34547226217 scopus 로고    scopus 로고
    • Biomarkers for disease modification trials-the innovative medicines initiative and AddNeuroMed
    • Lovestone S., et al. Biomarkers for disease modification trials-the innovative medicines initiative and AddNeuroMed. J. Nutr. Health Aging 11 (2007) 359-361
    • (2007) J. Nutr. Health Aging , vol.11 , pp. 359-361
    • Lovestone, S.1
  • 22
    • 34249808196 scopus 로고    scopus 로고
    • Personalized medicine: a perspective on the patient, disease and causal diagnostics
    • Online publication date: 1 May 2007
    • Liebman M.N. Personalized medicine: a perspective on the patient, disease and causal diagnostics. Personal. Med. 4 (2007) 171-174 Online publication date: 1 May 2007
    • (2007) Personal. Med. , vol.4 , pp. 171-174
    • Liebman, M.N.1
  • 23
    • 34948841986 scopus 로고    scopus 로고
    • Workflow based framework for life science informatics
    • Tiwari A., and Sekhar A.K.T. Workflow based framework for life science informatics. Comput. Biol. Chem. 31 (2007) 305-319
    • (2007) Comput. Biol. Chem. , vol.31 , pp. 305-319
    • Tiwari, A.1    Sekhar, A.K.T.2
  • 24
    • 51449085603 scopus 로고    scopus 로고
    • Biomarker discovery for athlerosclerosis
    • Manchester, United Kingdom, 14-15th May
    • Stubbs A. Biomarker discovery for athlerosclerosis. Proceedings of 8th European Biomarker Congress. Manchester, United Kingdom, 14-15th May (2008)
    • (2008) Proceedings of 8th European Biomarker Congress
    • Stubbs, A.1
  • 25
    • 6344278614 scopus 로고    scopus 로고
    • Biomedical informatics: development of a comprehensive data warehouse for clinical and genomic breast cancer research
    • Hu H., et al. Biomedical informatics: development of a comprehensive data warehouse for clinical and genomic breast cancer research. Pharmacogenomics 5 (2004) 933-941
    • (2004) Pharmacogenomics , vol.5 , pp. 933-941
    • Hu, H.1
  • 26
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14 000 cases of seven common diseases and 3000 shared controls
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14 000 cases of seven common diseases and 3000 shared controls. Nature 447 (2007) 661-678
    • (2007) Nature , vol.447 , pp. 661-678
    • Wellcome Trust Case Control Consortium1
  • 27
    • 51449098415 scopus 로고    scopus 로고
    • Building workflows for the quality control of genome wide association data
    • San Diego, USA, 23-27th October
    • Munro R., et al. Building workflows for the quality control of genome wide association data. Poster Presentation at American Society for Human Genetics. San Diego, USA, 23-27th October (2007)
    • (2007) Poster Presentation at American Society for Human Genetics
    • Munro, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.