SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 22, 2004, Pages 5599-5603

Identification of neutral 4-O-alkyl quinolone nonpeptide GnRH receptor antagonists

(15) DeVita, Robert J a Parikh, Mamta a Jiang, Jinlong a Fair, Jason A a Young, Jonathan R a Walsh, Thomas F a Goulet, Mark T a Lo, Jane L a Ren, Ning a Yudkovitz, Joel B a Cui, Jisong a Yang, Yi T a Cheng, Kang a Rohrer, Susan P a Wyvratt, Matthew J a

a MERCK RESEARCH LABORATORIES (United States)

Author keywords

Antagonist; GnRH; Quinolone

Indexed keywords

ALKYL GROUP; GONADORELIN ANTAGONIST; LACTAM DERIVATIVE; QUINOLONE DERIVATIVE;

ALKYLATION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG STRUCTURE; FEMALE; IN VITRO STUDY; MITSUNOBU REACTION; NONHUMAN;

HUMANS; MOLECULAR STRUCTURE; QUINOLONES; RECEPTORS, LHRH; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 5144235475 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2004.08.056 Document Type: Article

Times cited : (13)

References (19)

1
- 0015231127
- H. Matsu, Y. Baba, R.M.G. Nair, A. Arimura, and A.V. Schally Biophys. Res. Commun. 43 1971 1334
- (1971) Biophys. Res. Commun. , vol.43 , pp. 1334
- Matsu, H.¹ Baba, Y.² Nair, R.M.G.³ Arimura, A.⁴ Schally, A.V.⁵

2
- 0029195645
- G. Litwack Academic New York
- P.M. Conn, J.A. Janovick, D. Stanislaus, D. Kuphal, and L. Jennes G. Litwack Vitamins and Hormones Vol. 50 1995 Academic New York 151 214
- (1995) Vitamins and Hormones , vol.50 , pp. 151-214
- Conn, P.M.¹ Janovick, J.A.² Stanislaus, D.³ Kuphal, D.⁴ Jennes, L.⁵

3
- 0028092770
- S.S. Stojikovic, J. Reinhart, and K.J. Catt Endocrine Rev. 15 1994 462 499
- (1994) Endocrine Rev. , vol.15 , pp. 462-499
- Stojikovic, S.S.¹ Reinhart, J.² Catt, K.J.³

4
- 0026098581
- For a review: P.M. Conn, and W.F. Crowley Jr. N. Engl. J. Med. 324 1991 93
- (1991) N. Engl. J. Med. , vol.324 , pp. 93
- Conn, P.M.¹ Crowley Jr., W.F.²

5
- 0035944837
- J.A.F. Huirne, and C. Lambalk Lancet 358 2001 1793 1803
- (2001) Lancet , vol.358 , pp. 1793-1803
- Huirne, J.A.F.¹ Lambalk, C.²

6
- 1242352550
- Y.-F. Zhu, and C. Chen Expert Opin. Ther. Patents 14 2004 187 199
- (2004) Expert Opin. Ther. Patents , vol.14 , pp. 187-199
- Zhu, Y.-F.¹ Chen, C.²

7
- 10744224398
- See also J.T. Randolph, P. Waid, C. Nichols, D. Sauer, F. Haviv, G. Diaz, G. Bammert, L.M. Besecke, J.A. Segreti, K.M. Mohning, E.N. Bush, C.D. Wegner, and J. Greer J. Med. Chem. 47 2004 1085
- (2004) J. Med. Chem. , vol.47 , pp. 1085
- Randolph, J.T.¹ Waid, P.² Nichols, C.³ Sauer, D.⁴ Haviv, F.⁵ Diaz, G.⁶ Bammert, G.⁷ Besecke, L.M.⁸ Segreti, J.A.⁹ Mohning, K.M.¹⁰ Bush, E.N.¹¹ Wegner, C.D.¹² Greer, J.¹³

8
- 10744221952
- Z. Guo, Y.-F. Zhu, T.D. Gross, F.C. Tucci, Y. Gao, M. Moorjani, P.J. Connors Jr., M.W. Rowbottom, Y. Chen, R.S. Struthers, Q. Xie, J. Saunders, G. Reinhart, T.K. Chen, A.L. Killam Bonneville, and C. Chen J. Med. Chem. 47 2004 1259
- (2004) J. Med. Chem. , vol.47 , pp. 1259
- Guo, Z.¹ Zhu, Y.-F.² Gross, T.D.³ Tucci, F.C.⁴ Gao, Y.⁵ Moorjani, M.⁶ Connors Jr., P.J.⁷ Rowbottom, M.W.⁸ Chen, Y.⁹ Struthers, R.S.¹⁰ Xie, Q.¹¹ Saunders, J.¹² Reinhart, G.¹³ Chen, T.K.¹⁴ Killam Bonneville, A.L.¹⁵ Chen, C.¹⁶

9
- 11144358660
- M.W. Rowbottom, F.C. Tucci, Y.-F. Zhu, Z. Guo, T.D. Gross, G.J. Reinhart, Q. Xie, R.S. Struthers, J. Saunders, and C. Chen Bioorg. Med. Chem. Lett. 14 2004 2269
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 2269
- Rowbottom, M.W.¹ Tucci, F.C.² Zhu, Y.-F.³ Guo, Z.⁴ Gross, T.D.⁵ Reinhart, G.J.⁶ Xie, Q.⁷ Struthers, R.S.⁸ Saunders, J.⁹ Chen, C.¹⁰

10
- 3042647364
- F.C. Tucci, Y.-F. Zhu, Z. Guo, T.D. Gross, P.J. Connors Jr., Y. Gao, M.W. Rowbottom, R.S. Struthers, G.J. Reinhart, Q. Xie, T.K. Chen, H. Bozigian, A.L. Killam Bonneville, A. Fisher, L. Jin, J. Saunders, and C. Chen J. Med. Chem. 47 2004 3483
- (2004) J. Med. Chem. , vol.47 , pp. 3483
- Tucci, F.C.¹ Zhu, Y.-F.² Guo, Z.³ Gross, T.D.⁴ Connors Jr., P.J.⁵ Gao, Y.⁶ Rowbottom, M.W.⁷ Struthers, R.S.⁸ Reinhart, G.J.⁹ Xie, Q.¹⁰ Chen, T.K.¹¹ Bozigian, H.¹² Killam Bonneville, A.L.¹³ Fisher, A.¹⁴ Jin, L.¹⁵ Saunders, J.¹⁶ Chen, C.¹⁷

11
- 4444368194
- M.W. Rowbottom, F.C. Tucci, P.J. Connors Jr., T.D. Gross, Y.-F. Zhu, Z. Guo, M. Moorjani, O. Acevedo, L. Carter, S.K. Sullivan, Q. Xie, A. Fisher, R.S. Struthers, J. Saunders, and C. Chen Bioorg. Med. Chem. Lett. 14 2004 4967 4973
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 4967-4973
- Rowbottom, M.W.¹ Tucci, F.C.² Connors Jr., P.J.³ Gross, T.D.⁴ Zhu, Y.-F.⁵ Guo, Z.⁶ Moorjani, M.⁷ Acevedo, O.⁸ Carter, L.⁹ Sullivan, S.K.¹⁰ Xie, Q.¹¹ Fisher, A.¹² Struthers, R.S.¹³ Saunders, J.¹⁴ Chen, C.¹⁵

12
- 0033530102
- R.J. DeVita, D.D. Hollings, M.T. Goulet, M.J. Wyvratt, M.H. Fisher Jr., J. Lo, Y.T. Yang, K. Cheng, and R.G. Smith Bioorg. Med. Chem. Lett. 9 1999 2615
- (1999) Bioorg. Med. Chem. Lett. , vol.9 , pp. 2615
- Devita, R.J.¹ Hollings, D.D.² Goulet, M.T.³ Wyvratt, M.J.⁴ Fisher Jr., M.H.⁵ Lo, J.⁶ Yang, Y.T.⁷ Cheng, K.⁸ Smith, R.G.⁹

13
- 0033530138
- R.J. DeVita, M.T. Goulet, M.J. Wyvratt Jr., M.H. Fisher, J. Lo, Y.T. Yang, K. Cheng, and R.G. Smith Bioorg. Med. Chem. Lett. 9 1999 2621
- (1999) Bioorg. Med. Chem. Lett. , vol.9 , pp. 2621
- Devita, R.J.¹ Goulet, M.T.² Wyvratt Jr., M.J.³ Fisher, M.H.⁴ Lo, J.⁵ Yang, Y.T.⁶ Cheng, K.⁷ Smith, R.G.⁸

14
- 0035866652
- R.J. DeVita, T.F. Walsh, J.R. Young, J. Jiang, F. Ujjainwalla, R.B. Toupence, M. Parikh, S.X. Huang, J.A. Fair, M.T. Goulet, M.J. Wyvratt, J. Lo, N. Ren, J.B. Yudkovitz, Y.T. Yang, K. Cheng, J. Cui, G. Mount, S.P. Rohrer, J.M. Schaeffer, L. Rhodes, J.E. Drisko, E. McGowan, D.E. MacIntyre, S. Vincent, J.R. Carlin, J. Cameron, and R.G. Smith J. Med. Chem. 44 2001 917
- (2001) J. Med. Chem. , vol.44 , pp. 917
- Devita, R.J.¹ Walsh, T.F.² Young, J.R.³ Jiang, J.⁴ Ujjainwalla, F.⁵ Toupence, R.B.⁶ Parikh, M.⁷ Huang, S.X.⁸ Fair, J.A.⁹ Goulet, M.T.¹⁰ Wyvratt, M.J.¹¹ Lo, J.¹² Ren, N.¹³ Yudkovitz, J.B.¹⁴ Yang, Y.T.¹⁵ Cheng, K.¹⁶ Cui, J.¹⁷ Mount, G.¹⁸ Rohrer, S.P.¹⁹ Schaeffer, J.M.²⁰ more..

15
- 0034611086
- T.F. Walsh, R.B. Toupence, J.R. Young, S.X. Huabg, R.J. DeVita, D.D. Hollings, M.T. Goulet, M.J. Wyvratt Jr., M.H. Fisher, J. Lo, J. Cui, N. Ren, J.B. Yudkovitz, Y.T. Yang, K. Cheng, and R.G. Smith Bioorg. Med. Chem. Lett. 10 2000 443
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 443
- Walsh, T.F.¹ Toupence, R.B.² Young, J.R.³ Huabg, S.X.⁴ Devita, R.J.⁵ Hollings, D.D.⁶ Goulet, M.T.⁷ Wyvratt Jr., M.J.⁸ Fisher, M.H.⁹ Lo, J.¹⁰ Cui, J.¹¹ Ren, N.¹² Yudkovitz, J.B.¹³ Yang, Y.T.¹⁴ Cheng, K.¹⁵ Smith, R.G.¹⁶

16
- 0034618152
- J.R. Young, S.X. Huang, I. Chen, N. Ren, T.F. Walsh, R.J. DeVita, D.D. Hollings, M.J. Wyvratt Jr., M.T. Goulet, N. Ren, J. Lo, Y.T. Yang, J.B. Yudkovitz, K. Cheng, and R.G. Smith Bioorg. Med. Chem. Lett. 10 2000 1723
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 1723
- Young, J.R.¹ Huang, S.X.² Chen, I.³ Ren, N.⁴ Walsh, T.F.⁵ Devita, R.J.⁶ Hollings, D.D.⁷ Wyvratt Jr., M.J.⁸ Goulet, M.T.⁹ Ren, N.¹⁰ Lo, J.¹¹ Yang, Y.T.¹² Yudkovitz, J.B.¹³ Cheng, K.¹⁴ Smith, R.G.¹⁵

17
- 12144291081
- J. Jiang, R.J. DeVita, M.T. Goulet, M.J. Wyvratt, J.-L. Lo, N. Ren, J.B. Yudkovitz, J. Cui, Y.T. Yang, K. Cheng, and S.P. Rohrer Bioorg. Med. Chem. Lett. 14 2004 1795
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 1795
- Jiang, J.¹ Devita, R.J.² Goulet, M.T.³ Wyvratt, M.J.⁴ Lo, J.-L.⁵ Ren, N.⁶ Yudkovitz, J.B.⁷ Cui, J.⁸ Yang, Y.T.⁹ Cheng, K.¹⁰ Rohrer, S.P.¹¹

18
- 0003526242
- Originally disclosed San Francisco CA, Mar 26-30
- Originally disclosed at 219th ACS National Meeting, San Francisco CA, Mar 26-30, 2000
- (2000) 219th ACS National Meeting

19
- 5144220105
- note
- All compounds characterized by LC-MS and/or NMR

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.