Stability of nimodipine solution in oral syringes

American Journal of Health-System Pharmacy

Volumn 61, Issue 14, 2004, Pages 1493-1496

  Green, Amy E ^a,b   Banks, Stan ^c   Jay, Michael ^d,e   Hatton, Jimmi ^b,f  

^a Fresno Heart Hospital Community Medical Centers of Central California   (United States)

^b UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^c Division of Pharmaceutical Science

^d Ctr Pharmaceutical Sci Technol   (United States)

^e University of Kentucky   (United States)

^f UKCMC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCEROL; MACROGOL; NIMODIPINE; PEPPERMINT OIL; WATER; CALCIUM CHANNEL BLOCKING AGENT;

ARTICLE; DRUG CAPSULE; DRUG ISOLATION; DRUG STABILITY; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SYRINGE; CHEMISTRY; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; CALCIUM CHANNEL BLOCKERS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; NIMODIPINE; SYRINGES;

EID: 5144229099     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/61.14.1493     Document Type: Article

References (6)

1. Mayberg MR, Batjer HH, Dacey R et al. Guidelines for the management of aneurismal subarachnoid hemorrhage. A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke. 1994; 25:2315-28.
2. Nimotop (nimodipine) package insert. West Haven, CT: Bayer Corp.; 2001 Mar.
3. Institute for Safe Medication Practices. Using oral syringes won't necessarily protect against inadvertent IV injection of oral liquids. www.ismp.org/msaarticles/oral.html (accessed 2002 Sep 19).
4. Wanner-Olsen H, Gaarskaer FB, Mikkelsen EO et al. Studies on concentration-time profiles of nimodipine enantiomers following intravenous and oral administration of nimodipine in patients with subarachnoid hemorrhage. Chirality. 2000; 12:660-4.
5. Validation of compendial methods (general information chapter 1225). In: The United States pharmacopeia, 26th rev., and The national formulary, 21st ed. Rockville, MD: United States Pharmacopeial Convention; 2003:2440-2.
6. Phillips J, Beam S, Brinker A et al. Retrospective analysis of mortalities associated with medication errors. Am J Health-Syst Pharm. 2001; 58:1835-41. [Erratum, Am J Health-Syst Pharm. 2001; 58:2130.]