Macrocyclic ketone analogues of halichondrin B

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 22, 2004, Pages 5551-5554

  Zheng, Wanjun ^a   Seletsky, Boris M ^a   Palme, Monica H ^a   Lydon, Paul J ^a   Singer, Lori A ^a   Chase, Charles E ^a   Lemelin, Charles A ^a   Shen, Yongchun ^a   Davis, Heather ^a   Tremblay, Lynda ^a   Towle, Murray J ^a   Salvato, Kathleen A ^a   Wels, Bruce F ^a   Aalfs, Kimberley K ^a   Kishi, Yoshito ^a   Littlefield, Bruce A ^a   Yu, Melvin J ^a  

^a EISAI RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HALICHONDRIN B; KETONE DERIVATIVE; MACROCYCLIC COMPOUND;

ARTICLE; CELL GROWTH; DRUG CONFORMATION; DRUG EFFICACY; DRUG INHIBITION; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; GROWTH INHIBITION; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL DIVISION; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; ETHERS, CYCLIC; FURANS; HUMANS; KETONES; MACROCYCLIC COMPOUNDS; MICE; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 5144226671     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.08.069     Document Type: Article

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