Frequency of micronuclei in peripheral blood lymphocytes from subjects occupationally exposed to low levels of ionizing radiation

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 564, Issue 1, 2004, Pages 83-88

  Joseph, Lebana J ^a   Patwardhan, Uma N ^a   Samuel, Aban M ^b  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

^b Mumbai 400071 India   (India)

Author keywords

Ionizing radiation; Micronuclei; Occupational exposure; Peripheral lymphocytes

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINESIS; EMPLOYEE; FEMALE; GENDER; GENOTOXICITY; HUMAN; IONIZING RADIATION; MALE; MICRONUCLEUS; OCCUPATIONAL EXPOSURE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; SMOKING;

ADULT; AGE FACTORS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; LYMPHOCYTES; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; MIDDLE AGED; OCCUPATIONAL EXPOSURE; PERSONNEL, HOSPITAL; RADIATION, IONIZING; SMOKING;

EID: 5144220411     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2004.07.012     Document Type: Article

References (36)

1. J.F. Barquinero, L. Barrios, M.R. Caballin, R. Miro, M. Ribas, A. Subias, and J. Egozcue Cytogenetic analysis of lymphocytes from hospital workers occupationally exposed to low levels of ionizing radiation Mutat. Res. 286 1993 275 279
2. H. Thierens, A. Vral, and L. De Ridder A cytogenetic study of radiological workers: effect of age, smoking and radiation burden on the micronucleus frequency Mutat. Res. 360 1996 75 82
3. W.P. Chang, B.F. Hwang, D. Wang, and J.D. Wang Cytogenetic effect of chronic low-dose, low-dose-rate γ-radiation in residents of irradiated buildings Lancet 350 1997 330 333
4. H. Hessel, K. Radon, A. Pethran, B. Maisch, S. Grobmair, I. Sautter, and G. Fruhmann The genotoxic risk of hospital, pharmacy and medical personnel occupationally exposed to cytostatic drugs-evaluation by the micronucleus assay Mutat. Res. 497 2001 101 109
5. S. Pastor, S. Gutierrez, A. Creus, A. Cebulska-Wasilewska, and R. Marcos Micronuclei in peripheral blood lymphocytes and buccal epithelial cells of polish farmers exposed to pesticides Mutat. Res. 495 2001 147 156
6. H. Thierens, A. Vral, M. Barbe, M. Meijlaers, A. Baeyens, and L. De Ridder Chromosomal radiosensensitivity study of temporary nuclear workers and the support of the adaptive response induced by occupational exposure Int. J. Radiat. Biol. 78 2002 1117 1126
7. E. Severin Micronuclei frequency in peripheral blood lymphocytes from patients with systemic lupus erythematosus Romanian J. Morphol. Embryol. 41 1995 55 58
8. T.J. Cheng, D.C. Christiani, X. Xu, J.C. Wain, J.K. Wiencke, and K.T. Kelsey Increased micronucleus frequency in lymphocytes from smokers with lung cancer Mutat. Res. 349 1996 43 50
9. F. Duffaud, T. Orisiere, P. Villani, A.L. Pelissier, F. Volot, R. Favre, and A. Botta Comparison between micronucleated lymphocyte rates observed in healthy subjects and cancer patients Mutagenesis 12 1997 227 231
10. S.S. Strom, K.R. Hess, A.J. Sigurdson, M.R. Spitz, and J.C. Liang Evaluation of sister chromatid exchange and chromosome breaks in a cohort of untreated Hodgkin's disease patients Cancer Epidemiol. Biomarkers Prev. 6 1997 291 293
11. S. Sardas, M. Yilmaz, U. Oztok, N. Cakir, and A.E. Karakaya Assessment of DNA strand breakage by comet assay in diabetic patients and the role of antioxidant supplementation Mutat. Res. 490 2001 123 129
12. G. Porciello, R. Scarpato, C. Ferri, F. Storino, F. Cagetti, G. Morozzi, F. Bellisai, L. Migliore, R. Marcolongo, and M. Galeazzi Spontaneous chromosome damage (micronuclei) in systemic sclerosis and Raynaud's phenomenon J. Rheumatol. 30 6 2003 1244 1247
13. M.J. Ramsey, D.H. Moore II, J.F. Briner, D.A. Lee, L.A. Olsen, J.R. Senft, and J.D. Tucker The effects of age and life style factors on the accumulation of cytogenetic damage as measured by chromosome painting Mutat. Res. 338 1995 95 106
14. M. Fenech, N. Holland, W.P. Chang, E. Zeiger, and S. Bonassi The HUman MicroNucleus Project - an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans Mutat. Res. 428 1999 271 283
15. H.C. Evans, K.E. Buckton, G.E. Hamitton, and A. Carothers Radiation induced chromosome aberrations in nuclear dockyard workers Nature (London) 277 1979 531 534
16. M. Bauchinger, I. Kolin-Gerresheim, E. Schmid, and J. Dresp Chromosome analyses of nuclear power plant workers Int. J. Radiat. Biol. 38 1980 577 581
17. D.C. Lloyd, R.J. Purrott, and E.J. Reeder The incidence of unstable aberrations in peripheral blood lymphocytes from unirradiated and occupationally exposed people Mutat. Res. 72 1980 523 532
18. J.S. Prosser, J.E. Moquet, D.C. Lloyd, and A.A. Edwards Radiation induction of micronuclei in human lymphocytes Mutat. Res. 199 1988 37 45
19. A.N. Jha, and T. Sharma Enhanced frequency of chromosome aberrations in workers occupationally exposed to diagnostic X-rays Mutat. Res. 260 1991 343 348
20. D. Kubelka, A. Fucic, and S. Milkovic-Kraus The value of cytogenetic monitoring versus film dosimetry in the hot zone of a nuclear power plant Mutat. Res. 283 1992 169 172
21. K. Al-Sabti, D.C. Lloyd, A.A. Edwards, and P. Stegnar A survey of lymphocyte chromosomal damage in Slovenian workers exposed to occupational clastogens Mutat. Res. 280 1992 215 223
22. A.D. deCruz, A.G. McArthur, C.C. Silva, M.P. Curado, and B.W. Glickman Human micronucleus counts are correlated with age, smoking and cesium-137 dose in the Goania (Brazil) radiological accident Mutat. Res. 313 1994 57 68
23. M. Fenech, and A.A. Morley Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo aging and low dose X-irradiation Mutat. Res. 161 1986 193 198
24. A. Vral, H. Thierens, and L. DeRidder The in vitro micronucleus- centromere assay to detect radiation damage induced by low doses in human lymphocytes Int. J. Radiat. Biol. 71 1997 61 68
25. M. Fenech, and A.A. Morley Measurement of micronuclei in lymphocytes Mutat. Res. 147 1985 29 36
26. A.P. Krishnaja, and N.K. Sharma On the optimization and application of sister chromatid exchanges (SCEs) and cytokinesis blocked micronuclei (CBMN) in human lymphocytes for cytogenetic monitoring P.S. Chauhan P.M. Gopinath Environmental Mutagenesis and Carcinogenesis 1998 Quest Publication 77 90
27. H.W. Gantenberg, K. Wuttke, C. Streffer, and W.U. Muller Micronuclei in human lymphocytes irradiated in vitro or in vivo Radiat. Res. 128 1991 276 281
28. H. Thierens, A. Vral, M. Van Eijkeren, E. Speleman, and L. De Ridder Micronucleus induction in peripheral blood lymphocytes of patients under radiotherapy treatment for cervical cancer or Hodgkin's disease Int. J. Radiat. Biol. 67 1995 529 539
29. H. Huber, H. Braselmann, and M. Bauchinger Intra- and inter-individual variation of background and radiation-induced micronucleus frequencies in human lymphocytes Int. J. Radiat. Biol. 61 1992 655 661
30. M. Fenech, S. Neville, and J. Rinaldi Sex is an important variable affecting spontaneous micronucleus frequency in cytokinesis-blocked lymphocytes Mutat. Res. 313 1994 203 207
31. S. Bonassi, C. Bolognesi, A. Abbondandolo, R. Barale, P. Bigatti, L. Camurri, L. Dalpra, M. DeFerrari, A. Forni, C. Lando, P. Padovani, R. Pasquini, M. Stella, and R. Puntoni Influence of sex on cytogenetic end points: evidence from a large human ample and review of the literature Cancer Epidemiol. Biomarkers Prev. 4 1995 671 679
32. A. Norman, D. Bass, and D. Roe Screening human populations for chromosome aberrations Mutat. Res. 143 1985 155 160
33. L. Migliore, M. Parrini, I. Sbrana, C. Biagini, A. Battaglia, and N. Loprieno Micronucleated lymphocytes in people occupationally exposed to potential environmental contaminants: the age effect Mutat. Res. 256 1991 13 19
34. N. Bukvic, M. Gentile, F. Susca, M. Fanelli, G. Serio, L. Buonadonna, A. Capurso, and G. Guanti Sex chromosome loss, micronuclei, sister chromatid exchange and aging: a study including 16 centenarians Mutat. Res. 498 2001 159 167
35. E. Ron Ionizing radiation and cancer risk: evidence from epidemiology Radiat. Res. 150 1998 S30 S41
36. S. Cigarran, J.F. Barquinero, L. Barrios, M. Ribas, J. Egozcue, and M.R. Caballin Cytogenetic analysis by fluorescence in situ hybridization (FISH) in hospital workers occupationally exposed to low levels of ionizing radiation Radiat. Res. 155 2001 417 423