-
1
-
-
0024558306
-
Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule
-
Benchimol S, Fuks A, Jothy S et al. Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule. Cell 57, 327-332 (1989).
-
(1989)
Cell
, vol.57
, pp. 327-332
-
-
Benchimol, S.1
Fuks, A.2
Jothy, S.3
-
2
-
-
0031772993
-
Enhanced T-cell immunogenicity and protective efficacy of a human immunodeficiency virus type1 vaccine regimen consisting of consecutive priming with DNA and boosting with recombinant fowlpox virus
-
Kent SJ, Zhao A, Best SJ et al. Enhanced T-cell immunogenicity and protective efficacy of a human immunodeficiency virus type1 vaccine regimen consisting of consecutive priming with DNA and boosting with recombinant fowlpox virus. J. Virol. 72, 10180-10188 (1998).
-
(1998)
J. Virol
, vol.72
, pp. 10180-10188
-
-
Kent, S.J.1
Zhao, A.2
Best, S.J.3
-
3
-
-
0026085737
-
Efficacy studies on a canarypox-rabies recombinant virus
-
Taylor J, Trimarchi C, Weinberg R et al. Efficacy studies on a canarypox-rabies recombinant virus. Vaccine 9, 190-193 (1991).
-
(1991)
Vaccine
, vol.9
, pp. 190-193
-
-
Taylor, J.1
Trimarchi, C.2
Weinberg, R.3
-
4
-
-
0025871155
-
A recombinant vaccinia virus expressing human carcinoembryonic antigen (CEA)
-
Kaufman H, Schlom J, Kantor J. A recombinant vaccinia virus expressing human carcinoembryonic antigen (CEA). Int. J. Cancer 48, 900-907 (1991).
-
(1991)
Int. J. Cancer
, vol.48
, pp. 900-907
-
-
Kaufman, H.1
Schlom, J.2
Kantor, J.3
-
5
-
-
0026650448
-
Antitumor activity and immune responses induced by a recombinant carcinoembryonic antigen-vaccinia virus vaccine
-
Kantor J, Irvine K, Abrams S et al. Antitumor activity and immune responses induced by a recombinant carcinoembryonic antigen-vaccinia virus vaccine. J. Natl Cancer Inst. 84, 1084-1091 (1992).
-
(1992)
J. Natl Cancer Inst
, vol.84
, pp. 1084-1091
-
-
Kantor, J.1
Irvine, K.2
Abrams, S.3
-
6
-
-
0029042336
-
Generation of human cytotoxic T cells specific for human carcinoembryonic antigen epitopes from patients immunized with recombinant vaccinia-CEA vaccine
-
Tsang KY, Zaremba S, Nieroda CA et al. Generation of human cytotoxic T cells specific for human carcinoembryonic antigen epitopes from patients immunized with recombinant vaccinia-CEA vaccine. J. Natl Cancer Inst. 87, 982-990 (1995).
-
(1995)
J. Natl Cancer Inst
, vol.87
, pp. 982-990
-
-
Tsang, K.Y.1
Zaremba, S.2
Nieroda, C.A.3
-
7
-
-
0033571120
-
A triad of costimulatory molecules synergize to amplify T-cell activation
-
Hodge JW, Sabzevari H, Yafal AG et al. A triad of costimulatory molecules synergize to amplify T-cell activation. Cancer Res. 59, 5800-5807 (1999).
-
(1999)
Cancer Res
, vol.59
, pp. 5800-5807
-
-
Hodge, J.W.1
Sabzevari, H.2
Yafal, A.G.3
-
8
-
-
0034122338
-
Pilot study of a dual gene recombinant avipox vaccine containing both carcinoembryonic antigen (CEA) and B 7.1 transgenes in patients with recurrent CEA-expressing adenocarcinomas
-
Von Mehren M, Arlen P, Tsang KY et al. Pilot study of a dual gene recombinant avipox vaccine containing both carcinoembryonic antigen (CEA) and B 7.1 transgenes in patients with recurrent CEA-expressing adenocarcinomas. Clin. Cancer Res. 6, 2219-2228 (2000).
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 2219-2228
-
-
Von Mehren, M.1
Arlen, P.2
Tsang, K.Y.3
-
9
-
-
0033104972
-
Induction of anti-tumor immunity elicited by tumor cells expressing a murine LFA-3 analog via a recombinant vaccinia virus
-
Lorenz MG, Kantor JA, Schlom J et al. Induction of anti-tumor immunity elicited by tumor cells expressing a murine LFA-3 analog via a recombinant vaccinia virus. Hum. Gene Ther. 10, 623-631 (1999).
-
(1999)
Hum. Gene Ther
, vol.10
, pp. 623-631
-
-
Lorenz, M.G.1
Kantor, J.A.2
Schlom, J.3
-
10
-
-
0030972813
-
Construction and characterization of a recombinant vaccinia virus expressing murine intercellular adhesion molecule-1: Induction and potentiation of antitumor responses
-
Uzendoski K, Kantor JA, Abrams SI et al. Construction and characterization of a recombinant vaccinia virus expressing murine intercellular adhesion molecule-1: induction and potentiation of antitumor responses. Hum. Gene Ther. 8, 851-860 (1997).
-
(1997)
Hum. Gene Ther
, vol.8
, pp. 851-860
-
-
Uzendoski, K.1
Kantor, J.A.2
Abrams, S.I.3
-
11
-
-
0032697559
-
Comparative studies of a retrovirus versus a poxvirus vector in whole tumor-cell vaccines
-
Hodge JW, Schlom J. Comparative studies of a retrovirus versus a poxvirus vector in whole tumor-cell vaccines. Cancer Res. 59, 5106-5111 (1999).
-
(1999)
Cancer Res
, vol.59
, pp. 5106-5111
-
-
Hodge, J.W.1
Schlom, J.2
-
12
-
-
0032944458
-
Phase I study in cancer patients of a replication-defective avipox recombinant vaccine that expresses human carcinoembryonic antigen
-
Marshall JL, Hawkins MJ, Tsang KY et al. Phase I study in cancer patients of a replication-defective avipox recombinant vaccine that expresses human carcinoembryonic antigen. J. Clin. Oncol. 17, 332-337 (1999).
-
(1999)
J. Clin. Oncol
, vol.17
, pp. 332-337
-
-
Marshall, J.L.1
Hawkins, M.J.2
Tsang, K.Y.3
-
13
-
-
0030988548
-
Diversified prime and boost protocols using recombinant vaccinia virus and recombinant nonreplicating avian pox virus to enhance T cell immunity and antitumor responses
-
Hodge JW, McLaughlin JP, Kantor JA. Diversified prime and boost protocols using recombinant vaccinia virus and recombinant nonreplicating avian pox virus to enhance T cell immunity and antitumor responses. Vaccine 16, 759-768 (1997).
-
(1997)
Vaccine
, vol.16
, pp. 759-768
-
-
Hodge, J.W.1
McLaughlin, J.P.2
Kantor, J.A.3
-
14
-
-
0034551730
-
Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox to elicit anticarcinogenic antigen immune responses
-
Key article establishing both prime and boost and granulocyte-macrophage colony-stimulating factor impact on immune responses, •
-
Marshall JL, Hoyer RJ, Toomey MA et al. Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox to elicit anticarcinogenic antigen immune responses. J. Clin. Oncol. 18, 3964-3973 (2000). • Key article establishing both prime and boost and granulocyte-macrophage colony-stimulating factor impact on immune responses.
-
(2000)
J. Clin. Oncol
, vol.18
, pp. 3964-3973
-
-
Marshall, J.L.1
Hoyer, R.J.2
Toomey, M.A.3
-
15
-
-
0037108688
-
Vector-based vaccine/cytokine combination therapy to enhance induction of immune responses to a self antigen and antitumor activity
-
Aarts WM, Schlom J, Hodge JW. Vector-based vaccine/cytokine combination therapy to enhance induction of immune responses to a self antigen and antitumor activity. Cancer Res. 62, 5770-5777 (2002).
-
(2002)
Cancer Res
, vol.62
, pp. 5770-5777
-
-
Aarts, W.M.1
Schlom, J.2
Hodge, J.W.3
-
16
-
-
0034122338
-
Pilot study of a dual gene recombinant avipox vaccine containing both carcinoembryonic antigen (CEA) and B7.1 transgenes in patients with recurrent CEA-expressing adenocarcinomas
-
von Mehren M, Arlen P, Tsang KY et al. Pilot study of a dual gene recombinant avipox vaccine containing both carcinoembryonic antigen (CEA) and B7.1 transgenes in patients with recurrent CEA-expressing adenocarcinomas. Clin. Cancer Res. 6, 2219-2228 (2000).
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 2219-2228
-
-
von Mehren, M.1
Arlen, P.2
Tsang, K.Y.3
-
17
-
-
20044364936
-
Phase I study of sequential vaccinations with fowlpox -CEA (6D)-TRICOM alone and sequentially with vaccinia-CEA (6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas
-
Key article establishing costimulatory molecules and tumor burden impact on immune responses, •
-
Marshall JL, Gulley JL, Arlen PM et al. Phase I study of sequential vaccinations with fowlpox -CEA (6D)-TRICOM alone and sequentially with vaccinia-CEA (6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas. J. Clin. Oncol. 23, 720-731 (2005). • Key article establishing costimulatory molecules and tumor burden impact on immune responses.
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 720-731
-
-
Marshall, J.L.1
Gulley, J.L.2
Arlen, P.M.3
-
19
-
-
0033563771
-
Presentation of MUC1 tumor antigen by class I MHC and CTL function correlate with the glycosylation state of the protein taken up by dendritic cells
-
Hiltbold EM, Alter MD, Ciborowski P et al. Presentation of MUC1 tumor antigen by class I MHC and CTL function correlate with the glycosylation state of the protein taken up by dendritic cells. Cell. Immunol. 194, 143-149 (1999).
-
(1999)
Cell. Immunol
, vol.194
, pp. 143-149
-
-
Hiltbold, E.M.1
Alter, M.D.2
Ciborowski, P.3
-
20
-
-
38849160991
-
Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer
-
Kaufman HL, Kim-Schulze S, Manson K et al. Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer. J. Transl. Med. 5, 60 (2007).
-
(2007)
J. Transl. Med
, vol.5
, pp. 60
-
-
Kaufman, H.L.1
Kim-Schulze, S.2
Manson, K.3
-
21
-
-
49649090374
-
Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxvirus-based vaccines in patients with metastatic carcinoma
-
Gulley JK, Arlen PM, Tsang KY et al. Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxvirus-based vaccines in patients with metastatic carcinoma. Clin. Cancer Res. 14(10), 3060-3069 (2008).
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.10
, pp. 3060-3069
-
-
Gulley, J.K.1
Arlen, P.M.2
Tsang, K.Y.3
-
22
-
-
0015956495
-
Towards a network theory of the immune system
-
Jerne NK. Towards a network theory of the immune system. Ann. Immunology 125C, 373-389 (1974).
-
(1974)
Ann. Immunology
, vol.125 C
, pp. 373-389
-
-
Jerne, N.K.1
-
23
-
-
0009881031
-
Speculations on idiotypes and homobodies
-
Lindenmann J. Speculations on idiotypes and homobodies. Ann. Immunology 124, 171-184 (1973).
-
(1973)
Ann. Immunology
, vol.124
, pp. 171-184
-
-
Lindenmann, J.1
-
24
-
-
0025036276
-
Murine monoclonal anti-idiotype antibody as a potential network antigen for human carcinoembryonic antigen
-
Bhattacharya-Chatterjee M, Mukerjee S, Biddle W et al. Murine monoclonal anti-idiotype antibody as a potential network antigen for human carcinoembryonic antigen. J. Immunol. 145(8), 2758-2765 (1990).
-
(1990)
J. Immunol
, vol.145
, Issue.8
, pp. 2758-2765
-
-
Bhattacharya-Chatterjee, M.1
Mukerjee, S.2
Biddle, W.3
-
25
-
-
0029144584
-
Immune response to the carcinoembryonic antigen in patients treated with an anti-idiotype antibody vaccine
-
Foon KA, Chakraborty M, John WJ et al. Immune response to the carcinoembryonic antigen in patients treated with an anti-idiotype antibody vaccine. J. Clin. Invest. 96(1), 334-342 (1995).
-
(1995)
J. Clin. Invest
, vol.96
, Issue.1
, pp. 334-342
-
-
Foon, K.A.1
Chakraborty, M.2
John, W.J.3
-
26
-
-
0030746260
-
Clinical and immune responses in advanced colorectal cancer patients treated with anti-idiotype monoclonal antibody vaccine that mimics the carcinoembryonic antigen
-
Foon KA, John WJ, Chakraborty M et al. Clinical and immune responses in advanced colorectal cancer patients treated with anti-idiotype monoclonal antibody vaccine that mimics the carcinoembryonic antigen. Clin. Cancer Res. 3(8), 1267-1276 (1997).
-
(1997)
Clin. Cancer Res
, vol.3
, Issue.8
, pp. 1267-1276
-
-
Foon, K.A.1
John, W.J.2
Chakraborty, M.3
-
27
-
-
9644277675
-
Immune responses in advanced colorectal cancer following repeated intradermal vaccination with the anti-CEA murine monoclonal antibody, PR1A3: Results of a Phase I study
-
Zbar AP, Thomas H, Wilkinson RW et al. Immune responses in advanced colorectal cancer following repeated intradermal vaccination with the anti-CEA murine monoclonal antibody, PR1A3: results of a Phase I study. Int. J. Colorectal Dis. 20(5), 403-414 (2005).
-
(2005)
Int. J. Colorectal Dis
, vol.20
, Issue.5
, pp. 403-414
-
-
Zbar, A.P.1
Thomas, H.2
Wilkinson, R.W.3
-
28
-
-
0032877667
-
Clinical and immune responses in resected colon cancer patients treated with anti-idiotype monoclonal antibody vaccine that mimics the carcinoembryonic antigen
-
Foon KA, John WJ, Chakraborty M et al. Clinical and immune responses in resected colon cancer patients treated with anti-idiotype monoclonal antibody vaccine that mimics the carcinoembryonic antigen. J. Clin. Oncol. 17(9), 2889-2895 (1999).
-
(1999)
J. Clin. Oncol
, vol.17
, Issue.9
, pp. 2889-2895
-
-
Foon, K.A.1
John, W.J.2
Chakraborty, M.3
-
29
-
-
38049103772
-
A Phase II prospective multi-institutional trial of adjuvant active specific immunotherapy following curative resection of colorectal cancer hepatic metastases: Cancer and leukemia group B study 89903
-
Demonstrates the selection of proper patients, •
-
Posner MC, Niedzwiecki D, Venook AP et al. A Phase II prospective multi-institutional trial of adjuvant active specific immunotherapy following curative resection of colorectal cancer hepatic metastases: cancer and leukemia group B study 89903. Ann. Surg. Oncol. 15(1), 158-164 (2008). • Demonstrates the selection of proper patients.
-
(2008)
Ann. Surg. Oncol
, vol.15
, Issue.1
, pp. 158-164
-
-
Posner, M.C.1
Niedzwiecki, D.2
Venook, A.P.3
-
30
-
-
0038615871
-
Murine dendritic cells pulsed with an anti-idiotype antibody induce antigen-specific protective antitumor immunity
-
Highlights the importance of dendritic cells, •
-
Saha A, Chatterjee SK, Foon KA et al. Murine dendritic cells pulsed with an anti-idiotype antibody induce antigen-specific protective antitumor immunity. Cancer Res. 63(11), 2844-2854 (2003). • Highlights the importance of dendritic cells.
-
(2003)
Cancer Res
, vol.63
, Issue.11
, pp. 2844-2854
-
-
Saha, A.1
Chatterjee, S.K.2
Foon, K.A.3
-
31
-
-
33645743147
-
CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic mice
-
Saha A, Baral RN, Chatterjee SK et al. CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic mice. Cancer Immunol. Immunother. 55(5), 515-527 (2006).
-
(2006)
Cancer Immunol. Immunother
, vol.55
, Issue.5
, pp. 515-527
-
-
Saha, A.1
Baral, R.N.2
Chatterjee, S.K.3
-
32
-
-
34047266237
-
Therapy of established tumors in a novel murine model transgenic for human carcinoembryonic antigen and HLA-A2 with a combination of anti-idiotype vaccine and CTL peptides of carcinoembryonic antigen
-
Saha A, Chatterjee SK, Foon KA et al. Therapy of established tumors in a novel murine model transgenic for human carcinoembryonic antigen and HLA-A2 with a combination of anti-idiotype vaccine and CTL peptides of carcinoembryonic antigen. Cancer Res. 67(6), 2881-2892 (2007).
-
(2007)
Cancer Res
, vol.67
, Issue.6
, pp. 2881-2892
-
-
Saha, A.1
Chatterjee, S.K.2
Foon, K.A.3
-
33
-
-
0029042336
-
Generation of human cytotoxic T cells specific for human carcinoembryonic antigen epitopes from patients immunized with recombinant vaccinia-CEA vaccine
-
Tsang KY, Zaremba S, Nieroda CA et al. Generation of human cytotoxic T cells specific for human carcinoembryonic antigen epitopes from patients immunized with recombinant vaccinia-CEA vaccine. J. Natl Cancer Inst. 87(13), 982-990 (1995).
-
(1995)
J. Natl Cancer Inst
, vol.87
, Issue.13
, pp. 982-990
-
-
Tsang, K.Y.1
Zaremba, S.2
Nieroda, C.A.3
-
34
-
-
0033017065
-
A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen
-
Highlights the clinical utility of dendritic cells, •
-
Morse MA, Deng Y, Coleman D et al. A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen. Clin. Cancer Res. 5(6), 1331-1338 (1999). • Highlights the clinical utility of dendritic cells.
-
(1999)
Clin. Cancer Res
, vol.5
, Issue.6
, pp. 1331-1338
-
-
Morse, M.A.1
Deng, Y.2
Coleman, D.3
-
35
-
-
0035902607
-
Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy
-
Fong L, Hou Y, Rivas A et al. Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy. Proc. Natl Acad. Sci. USA 98(15), 8809-8814 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, Issue.15
, pp. 8809-8814
-
-
Fong, L.1
Hou, Y.2
Rivas, A.3
-
36
-
-
23844514389
-
Phase I/II combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-A2-restricted CAP-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal cancer
-
Weihrauch MR, Ansén S, Jurkiewicz E et al. Phase I/II combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-A2-restricted CAP-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal cancer. Clin. Cancer Res. 11(16), 5993-6001 (2005).
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.16
, pp. 5993-6001
-
-
Weihrauch, M.R.1
Ansén, S.2
Jurkiewicz, E.3
-
37
-
-
2542497798
-
Durable carcinoembryonic antigen (CEA)-specific humoral and cellular immune responses in colorectal carcinoma patients vaccinated with recombinant CEA and granulocyte/macrophage colony-stimulating factor
-
Ullenhag GJ, Frödin JE, Jeddi-Tehrani M et al. Durable carcinoembryonic antigen (CEA)-specific humoral and cellular immune responses in colorectal carcinoma patients vaccinated with recombinant CEA and granulocyte/macrophage colony-stimulating factor. Clin. Cancer Res. 10(10), 3273-3281 (2004).
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.10
, pp. 3273-3281
-
-
Ullenhag, G.J.1
Frödin, J.E.2
Jeddi-Tehrani, M.3
-
38
-
-
0041857805
-
Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA
-
Morse MA, Nair SK, Mosca PJ et al. Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA. Cancer Invest. 21(3), 341-349 (2003).
-
(2003)
Cancer Invest
, vol.21
, Issue.3
, pp. 341-349
-
-
Morse, M.A.1
Nair, S.K.2
Mosca, P.J.3
-
39
-
-
0036716966
-
Safety and immunogenicity of a DNA vaccine encoding carcinoembryonic antigen and hepatitis B surface antigen in colorectal carcinoma patients
-
Conry RM, Curiel DT, Strong TV et al. Safety and immunogenicity of a DNA vaccine encoding carcinoembryonic antigen and hepatitis B surface antigen in colorectal carcinoma patients. Clin. Cancer Res. 8(9), 2782-2787 (2002).
-
(2002)
Clin. Cancer Res
, vol.8
, Issue.9
, pp. 2782-2787
-
-
Conry, R.M.1
Curiel, D.T.2
Strong, T.V.3
-
40
-
-
33749537026
-
Phase I study of recombinant carcinoembryonic antigen (CEA) vaccinia virus vaccine with post vaccination carcinoembryonic antigen peptide (CAP-1) boost
-
Cole DJ, Baron PL, O'Brien P et al. Phase I study of recombinant carcinoembryonic antigen (CEA) vaccinia virus vaccine with post vaccination carcinoembryonic antigen peptide (CAP-1) boost. Clin. Lung Cancer 1(3), 227-229 (2000).
-
(2000)
Clin. Lung Cancer
, vol.1
, Issue.3
, pp. 227-229
-
-
Cole, D.J.1
Baron, P.L.2
O'Brien, P.3
|