Comparative study of ornidazole enantiomers on the toxic and side effects to central nervous system in mice

Journal of China Pharmaceutical University

Volumn 39, Issue 4, 2008, Pages 343-347

  Sun, Ji Hong ^a   Wang, Zhi Qiang ^b   Cu, Xing Li ^a   Mu, Rong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Nanjing Sanhome Pharmaceutical Co Ltd   (China)

Author keywords

(R) ornidazole; (S) ornidazole; Anticonvulsive effect; Nervous system; Sedative effect; Toxic and side effect

Indexed keywords

CHLORPROMAZINE; DIAZEPAM; DIMEFLINE; ISONIAZID; ORNIDAZOLE; PENTOBARBITAL; STRYCHNINE; THIOPENTAL; THIOSEMICARBAZIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; DRUG STRUCTURE; ENANTIOMER; EPILEPSY; EXPERIMENTAL MODEL; LOCOMOTION; MOUSE; NEUROTOXICITY; NONHUMAN; SEIZURE; SLEEP TIME; STRUCTURE ANALYSIS;

EID: 51349148403     PISSN: 10005048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. (Tian HP), (Wang MN). (Eval Anal Drug Use Hosp China),2002,2(5):303-304.
2. (Chen Y), (Shi T), (Liu XQ), (J China Pharm Univ),2006,37(1):41-44.
3. Adeyemi OO, Yemitan OK, Adebiyi OO. Sedative and anticonvulsant activities of the aqueous root extract of Sanseviera liberica Gerome & Labroy (Agavaceae) [J]. J Ethnopharmacol,2007, 113(1):111-114.
4. Chinese source.
5. Chinese source.
6. Chinese source.
7. (Huang Q), (Zhang JR). (Prog Physiol Sci),1985,16 (4):353-355.
8. (Zhan WZ), (Pan LH), (Zhang JR). (Prog Physiol Sci),1983,14(1):48-52.
9. (Li JY), (Zhao DR), (Nan TH). (Prog Physiol Sci), 1987,18(2):123-126.
10. (Hai P). (Chin J Mod Appl Pharm), 2003,20(1):3-5.