Duration of chronic inflammation alters gene expression in muscle from untreated girls with juvenile dermatomyositis

BMC Immunology

Volumn 9, Issue , 2008, Pages

  Chen, Yi Wen ^a,b   Shi, Rongye ^a   Geraci, Nicholas ^c   Shrestha, Sheela ^c   Gordish Dressman, Heather ^a   Pachman, Lauren M ^c  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CLUSTERIN; HLA DQA1 ANTIGEN; MYOSIN HEAVY CHAIN; PLEXIN; PLEXIN D1; TENOMODULIN; HLA DQ ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL MATURATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DERMATOMYOSITIS; DISEASE COURSE; DISEASE DURATION; FEMALE; GENE EXPRESSION PROFILING; GENE FUNCTION; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MUSCLE BIOPSY; NEOVASCULARIZATION (PATHOLOGY); PATHOPHYSIOLOGY; PROTEIN METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; STRESS; BLOOD; CELL DIFFERENTIATION; CHRONIC DISEASE; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; GENETICS; HOSPITALIZATION; IMMUNOLOGY; METABOLISM; PATHOLOGY; PRESCHOOL CHILD; TIME; VASCULARIZATION;

CELL DIFFERENTIATION; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; DENDRITIC CELLS; DERMATOMYOSITIS; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HLA-DQ ANTIGENS; HUMANS; MUSCLE, SKELETAL; NEOVASCULARIZATION, PATHOLOGIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, GENETIC; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 51349134921     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-9-43     Document Type: Article

References (52)

1. Bohan A Peter JB Polymyositis and dermatomyositis (first of two parts) N Engl J Med 1975 292 7 344 347 1090839
2. Mendez EP Lipton R Ramsey-Goldman R Roettcher P Bowyer S Dyer A Pachman LM US incidence of juvenile dermatomyositis, 1995-1998: Results from the National Institute of Arthritis and Musculoskeletal and Skin Diseases Registry Arthritis Rheum 2003, 49(3):300-305. 10.1002/art.11122 12794783
3. Pachman LM Hayford JR Chung A Daugherty CA Pallansch MA Fink CW Gewanter HL Jerath R Lang BA Sinacore J Szer IS Dyer AR Hochberg MC Juvenile dermatomyositis at diagnosis: Clinical characteristics of 79 children J Rheumatol 1998, 25(6):1198-1204. 9632086
4. Bode RK Klein-Gitelman MS Miller ML Lechman TS Pachman LM Disease activity score for children with juvenile dermatomyositis: Reliability and validity evidence Arthritis Rheum 2003, 49(1):7-15. 10.1002/ art.10924 12579588
5. Pachman LM Lipton R Ramsey-Goldman R Shamiyeh E Abbott K Mendez EP Dyer A Curdy DM Vogler L Reed A Cawkwell G Zemel L Sandborg C Rivas-Chacon R Hom C Ilowite N Gedalia A Gitlin J Borzy M History of infection before the onset of juvenile dermatomyositis: Results from the National Institute of Arthritis and Musculoskeletal and Skin Diseases Research Registry Arthritis Rheum 2005, 53(2):166-172. 10.1002/art.21068 15818654
6. Reed AM Pachman L Ober C Molecular genetic studies of major histocompatibility complex genes in children with juvenile dermatomyositis: Increased risk associated with HLA-DQA1 *0501 Hum Immunol 1991, 32(4):235-240. 10.1016/0198-8859(91)90085-N 1783570
7. Reed AM Stirling JD Association of the HLA-DQA1*0501 allele in multiple racial groups with juvenile dermatomyositis Hum Immunol 1995, 44(3):131-135. 10.1016/0198-8859(95)00035-6 8666549
8. Tezak Z Hoffman EP Lutz JL Fedczyna TO Stephan D Bremer EG Krasnoselska-Riz I Kumar A Pachman LM Gene expression profiling in DQA1*0501+ children with untreated dermatomyositis: A novel model of pathogenesis J Immunol 2002, 168(8):4154-4163. 11937576
9. Greenberg SA Pinkus JL Pinkus GS Burleson T Sanoudou D Tawil R Barohn RJ Saperstein DS Briemberg HR Ericsson M Park P Amato AA Interferon-alpha/ beta-mediated innate immune mechanisms in dermatomyositis Ann Neurol 2005, 57(5):664-678. 10.1002/ana.20464 15852401
10. Pachman LM Abbott K Sinacore JM Amoruso L Dyer A Lipton R Ilowite N Hom C Cawkwell G White A Rivas-Chacon R Kimura Y Ray L Ramsey-Goldman R Duration of illness is an important variable for untreated children with juvenile dermatomyositis J Pediatr 2006, 148(2):247-253. 10.1016/ j.jpeds.2005.10.032 16492437
11. Ahn JH Lee Y Jeon C Lee SJ Lee BH Choi KD Bae YS Identification of the genes differentially expressed in human dendritic cell subsets by cDNA subtraction and microarray analysis Blood 2002, 100(5):1742-1754. 12176896
12. Chang SH Liu CH Wu MT Hla T Regulation of vascular endothelial cell growth factor expression in mouse mammary tumor cells by the EP2 subtype of the prostaglandin E2 receptor Prostaglandins Other Lipid Mediat 2005, 76(1-4):48-58. 15967161
13. Hayashi K Takahashi M Kimura K Nishida W Saga H Sobue K Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells J Cell Biol 1999, 145(4):727-740. 2133182 10330402 10.1083/jcb.145.4.727
14. Millis AJ Luciani M McCue HM Rosenberg ME Moulson CL Clusterin regulates vascular smooth muscle cell nodule formation and migration J Cell Physiol 2001, 186(2):210-219. 10.1002/ 1097-4652(200102)186:2<210::AID-JCP1019>3.0.CO;2-N 11169458
15. Miwa Y Taba Y Miyagi M Sasaguri T Physiology and pharmacology of the prostaglandin J2 family Nippon Yakurigaku Zasshi 2004, 123(1):34-40. 14695456
16. Owens GK Molecular control of vascular smooth muscle cell differentiation Acta Physiol Scand 1998, 164(4):623-635. 9887984
17. Ragolia L Palaia T Koutrouby TB Maesaka JK Inhibition of cell cycle progression and migration of vascular smooth muscle cells by prostaglandin D2 synthase: Resistance in diabetic Goto-Kakizaki rats Am J Physiol Cell Physiol 2004, 287(5):C1273-81. 10.1152/ajpcell.00230.2004 15240344
18. Shukunami C Oshima Y Hiraki Y Chondromodulin-I and tenomodulin: A new class of tissue-specific angiogenesis inhibitors found in hypovascular connective tissues Biochem Biophys Res Commun 2005, 333(2):299-307. 10.1016/j.bbrc.2005.05.133 15950187
19. Torres-Vazquez J Gitler AD Fraser SD Berk JD Van NP Fishman MC Childs S Epstein JA Weinstein BM Semaphorin-plexin signaling guides patterning of the developing vasculature Dev Cell 2004, 7(1):117-123. 10.1016/ j.devcel.2004.06.008 15239959
20. Sherman-Baust CA Weeraratna AT Rangel LB Pizer ES Cho KR Schwartz DR Shock T Morin PJ Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells Cancer Cell 2003, 3(4):377-386. 10.1016/ S1535-6108(03)00058-8 12726863
21. Silletti S Kessler T Goldberg J Boger DL Cheresh DA Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo Proc Natl Acad Sci U S A 2001, 98(1):119-124. 14554 11134507 10.1073/pnas.011343298
22. Pachman LM Friedman JM Maryjowski-Sweeney ML Jonnason O Radvany RM Sharp GC Cobb MA Battles ND Crowe WE Fink CW et al. Immunogenetic studies of juvenile dermatomyositis. III. Study of antibody to organ-specific and nuclear antigens Arthritis Rheum 1985, 28(2):151-157. 10.1002/ art.1780280208 3871616
23. Pachman LM Liotta-Davis MR Hong DK Kinsella TR Mendez EP Kinder JM Chen EH TNFalpha-308A allele in juvenile dermatomyositis: Association with increased production of tumor necrosis factor alpha, disease duration, and pathologic calcifications Arthritis Rheum 2000, 43(10):2368-2377. 10.1002/1529-0131(200010)43:10<2368::AID-ANR26>3.0.CO;2-8 11037898
24. Smith RL Sundberg J Shamiyah E Dyer A Pachman LM Skin involvement in juvenile dermatomyositis is associated with loss of end row nailfold capillary loops J Rheumatol 2004, 31(8):1644-1649. 15290747
25. Christen-Zaech S Seshadri R Sundberg J Paller AS Pachman LM Persistent association of nailfold capillaroscopy changes and skin involvement over thirty-six months with duration of untreated disease in patients with juvenile dermatomyositis Arthritis Rheum 2008, 58(2):571-576. 10.1002/ art.23299 18240225
26. Rouster-Stevens KA Gursahaney A Ngai KL Daru JA Pachman LM Pharmacokinetic study of oral prednisolone compared with intravenous methylprednisolone in patients with juvenile dermatomyositis Arthritis Rheum 2008, 59(2):222-226. 10.1002/art.23341 18240180
27. Zhao Y Fedczyna TO McVicker V Caliendo J Li H Pachman LM Apoptosis in the skeletal muscle of untreated children with juvenile dermatomyositis: Impact of duration of untreated disease Clin Immunol 2007, 125(2):165-172. 10.1016/j.clim.2007.06.011 17704000
28. Chen YW Zhao P Borup R Hoffman EP Expression profiling in the muscular dystrophies: Identification of novel aspects of molecular pathophysiology J Cell Biol 2000, 151(6):1321-1336. 2190600 11121445 10.1083/jcb.151.6.1321
29. St-Amand J Okamura K Matsumoto K Shimizu S Sogawa Y Characterization of control and immobilized skeletal muscle: An overview from genetic engineering Faseb J 2001, 15(3):684-692. 10.1096/fj.00-0150com 11259386
30. Nagaraju K Casciola-Rosen L Lundberg I Rawat R Cutting S Thapliyal R Chang J Dwivedi S Mitsak M Chen YW Plotz P Rosen A Hoffman E Raben N Activation of the endoplasmic reticulum stress response in autoimmune myositis: Potential role in muscle fiber damage and dysfunction Arthritis Rheum 2005, 52(6):1824-1835. 10.1002/art.21103 15934115
31. Lopez de Padilla CM Vallejo AN McNallan KT Vehe R Smith SA Dietz AB Vuk-Pavlovic S Reed AM Plasmacytoid dendritic cells in inflamed muscle of patients with juvenile dermatomyositis Arthritis Rheum 2007, 56(5):1658-1668. 10.1002/art.22558 17469160
32. Nagaraju K Rider LG Fan C Chen YW Mitsak M Rawat R Patterson K Grundtman C Miller FW Plotz PH Hoffman E Lundberg IE Endothelial cell activation and neovascularization are prominent in dermatomyositis J Autoimmune Dis 2006, 3:2. 1397829 16504012 10.1186/1740-2557-3-2
33. Quah BJ O'Neill HC Maturation of function in dendritic cells for tolerance and immunity J Cell Mol Med 2005, 9(3):643-654. 10.1111/ j.1582-4934.2005.tb00494.x 16202211
34. Ma L Chan KW Trendell-Smith NJ Wu A Tian L Lam AC Chan AK Lo CK Chik S Ko KH To CK Kam SK Li XS Yang CH Leung SY Ng MH Stott DI Macpherson GG Huang FP Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic cells in susceptible mouse strains Eur J Immunol 2005, 35(11):3364-3375. 10.1002/eji.200535192 16224814
35. Sarkar S Fox DA Dendritic cells in rheumatoid arthritis Front Biosci 2005, 10:656-665. 10.2741/1560 15569606
36. Zhuang H Narain S Sobel E Lee PY Nacionales DC Kelly KM Richards HB Segal M Stewart C Satoh M Reeves WH Association of anti-nucleoprotein autoantibodies with upregulation of Type I interferon-inducible gene transcripts and dendritic cell maturation in systemic lupus erythematosus Clin Immunol 2005, 117(3):238-250. 10.1016/ j.clim.2005.07.009 16126005
37. O'Connor KA Abbott KA Sabin B Kuroda M Pachman LM MxA gene expression in juvenile dermatomyositis peripheral blood mononuclear cells: Association with muscle involvement Clin Immunol 2006, 120(3):319-325. 10.1016/ j.clim.2006.05.011 16859997
38. Pascual V Allantaz F Arce E Punaro M Banchereau J Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade J Exp Med 2005, 201(9):1479-1486. 2213182 15851489 10.1084/jem.20050473
39. Pascual V Banchereau J Palucka AK The central role of dendritic cells and interferon-alpha in SLE Curr Opin Rheumatol 2003, 15(5):548-556. 10.1097/00002281-200309000-00005 12960479
40. Owens GK Kumar MS Wamhoff BR Molecular regulation of vascular smooth muscle cell differentiation in development and disease Physiol Rev 2004, 84(3):767-801. 10.1152/physrev.00041.2003 15269336
41. Eimer MJ Young L Abbott K Seshadri R Gursahney A Smulevitz B Rhew E Ramsey-Goldman R McPherson D Abnormal cardiovascular risk profiles in adult patients with juvenile dermatomyositis. Arthritis Rheum 2006. 54:S519 Abstract
42. Toyofuku T Yabuki M Kamei J Kamei M Makino N Kumanogoh A Hori M Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1 Embo J 2007, 26(5):1373-1384. 1817636 17318185 10.1038/sj.emboj.7601589
43. Park JW Cai J McIntosh I Jabs EW Fallin MD Ingersoll R Hetmanski JB Vekemans M Attie-Bitach T Lovett M Scott AF Beaty TH High throughput SNP and expression analyses of candidate genes for non-syndromic oral clefts J Med Genet 2006, 43(7):598-608. 10.1136/jmg.2005.040162 16415175
44. Bouma G Crusius JB Oudkerk Pool M Kolkman JJ von Blomberg BM Kostense PJ Giphart MJ Schreuder GM Meuwissen SG Pena AS Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease Scand J Immunol 1996, 43(4):456-463. 10.1046/ j.1365-3083.1996.d01-65.x 8668926
45. Wilson AG Symons JA McDowell TL McDevitt HO Duff GW Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation Proc Natl Acad Sci U S A 1997, 94(7):3195-3199. 20345 9096369 10.1073/pnas.94.7.3195
46. Tumor Analysis Best Practices Working Group Expression profiling--best practices for data generation and interpretation in clinical trials Nat Rev Genet 2004, 5(3):229-237. 14970825
47. Li C Hung Wong W Model-based analysis of oligonucleotide arrays: Model validation, design issues and standard error application Genome Biol 2001, 2(8):RESEARCH0032 55329 11532216
48. Benjamini Y Hochberg Y On the adaptive control of the false discovery rate: A practical and powerful approach to multiple testing. Journal of Educational and Behavioral Statistics 2000, 25:60-83.
49. Benjamini Y Hochberg Y Controlling the false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society 1995, Series B 57:289-300.
50. Wolf NS Penn PE Rao D McKee MD Intraclonal plasticity for bone, smooth muscle, and adipocyte lineages in bone marrow stroma fibroblastoid cells Exp Cell Res 2003, 290(2):346-357. 10.1016/S0014-4827(03)00321-5 14567992
51. July LV Beraldi E So A Fazli L Evans K English JC Gleave ME Nucleotide-based therapies targeting clusterin chemosensitize human lung adenocarcinoma cells both in vitro and in vivo Mol Cancer Ther 2004, 3(3):223-232. 15026542
52. Schneider S Yochim J Brabender J Uchida K Danenberg KD Metzger R Schneider PM Salonga D Holscher AH Danenberg PV Osteopontin but not osteonectin messenger RNA expression is a prognostic marker in curatively resected non-small cell lung cancer Clin Cancer Res 2004, 10(5):1588-1596. 10.1158/1078-0432.CCR-0565-3 15014008