Persistent monoclonality after histological remission in gastric mucosa-associated lymphoid tissue lymphoma treated with chemotherapy and/ or surgery: Influence of t(11;18)(q21;q21)

Leukemia and Lymphoma

Volumn 49, Issue 8, 2008, Pages 1516-1522

  Santón, Almudena ^a   García Cosio, Mónica ^a   Bellosillo, Beatriz ^b   Rodríguez, Patricia ^a   Cristóbal, Eva ^a   Serrano, Sergio ^b   Besses, Carlos ^b   Abraira, Victor ^a   Salar, Antonio ^b   Montalban, Carlos ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b HOSPITAL DEL MAR   (Spain)

Author keywords

Gastric lymphoma; H. pylori; MALT lymphoma; t(11; 18)(q21; q21)

Indexed keywords

CHLORAMBUCIL; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; FLUDARABINE; IMMUNOGLOBULIN HEAVY CHAIN; MITOXANTRONE; PREDNISONE; RITUXIMAB; VINCRISTINE;

ARTICLE; CANCER REGRESSION; CANCER STAGING; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 18; CLINICAL ARTICLE; CLONAL VARIATION; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GASTRECTOMY; GENE REARRANGEMENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; STOMACH LYMPHOMA; TREATMENT RESPONSE; TUMOR BIOPSY;

CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 18; CLONE CELLS; GENE REARRANGEMENT; HUMANS; IMMUNOGLOBULIN FRAGMENTS; LYMPHOMA, B-CELL, MARGINAL ZONE; PROGNOSIS; REMISSION INDUCTION; RETROSPECTIVE STUDIES; STOMACH NEOPLASMS; SURVIVORS; TRANSLOCATION, GENETIC;

EID: 51349099021     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190802210692     Document Type: Article

References (27)

1. Wotherspoon, A. C., Doglioni, C., Diss, T. C., Pan, L., Moschini, A. de Boni, M. et al. (1993) Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet, 342, pp. 575-577.
2. Bayerdorffer, E., Neubauer, A., Rudolph, B., Thiede, C., Lehn, N. Eidt, S. et al. (1995) Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. Lancet, 345, pp. 1591-1594.
3. Roggero, E., Zucca, E., Pinotti, G., Pascarella, A., Capella, C. Savio, A. et al. (1995) Eradication of Helicobacter pylori infection in primary low-grade gastric lymphoma of mucosa-associated lymphoid tissue. Ann Intern Med, 122, pp. 767-769.
4. Montalban, C., Santon, A., Boixeda, D., Redondo, C., Alvarez, I. Calleja, J. L. et al. (2001) Treatment of low-grade gastric mucosa-associated lymphoid tissue lymphoma in stage I with Helicobacter pylori eradication. Long-term results after sequential histological and molecular follow-up. Haematologica, 86, pp. 609-617.
5. Thiede, C., Wundisch, T., Alpen, B., Neubauer, B., Morgner, A. Schmitz, M. et al. (2001) Long-term persistence of monoclonal B cells after cure of Helicobacter pylori infection and complete histological remission in gastric mucosa-associated lymphoid tissue B-cell lymphoma. J Clin Oncol, 119, pp. 1600-1609.
6. Montalban, C., Santon, A., Redondo, C., Garcia-Cosio, M., Boixeda, D. Vazquez-Sequeiros, E. et al. (2005) Long-term persistence of molecular disease after histological remission in low grade gastric MALT lymphoma treated with H. pylori eradication. Lack of association with translocation t(11;18)(q21;q21): A 10-year updated follow-up of a prospective study. Ann Oncol, 16, pp. 1539-1544.
7. Wundisch, T., Thiede, C., Morgner, A., Dempfle, A., Gunther, A. Liu, H. et al. (2005) Long-term follow-up of gastric MALT lymphoma after Helicobacter pylori eradication. J Clin Oncol, 23, pp. 8018-8024.
8. Fischbach, W., Goebeler-Kolve, M. E., Dragosics, B., Greiner, A. and Stolte, M. (2004) Long term outcome of patients with gastric marginal zone B cell lymphoma of mucosa associated lymphoid tissue (MALT) following exclusive Helicobacter pylori eradication therapy: Experience from a large prospective series. Gut, 53, pp. 34-37.
9. Liu, H., Ye, H., Ruskone-Fourmestraux, A., De Jong, D., Pileri, S. Thiede, C. et al. (2002) T(11;18)(q21;q21) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication. Gastroenterology, 122, pp. 1286-1294.
10. Fischbach, W., Dragosics, B., Kolve-Goebeler, M. E., Ohmann, C., Greiner, A. Yang, Q. et al. (2000) Primary gastric B-cell lymphoma: results of a prospective multicenter study. Gastroenterology, 119, pp. 1191-1202.
11. Tsang, R. W., Gospodarowicz, M. K., Pintilie, M., Wells, W., Hodgson, D. C. Sun, A. et al. (2003) Localized mucosa-associated lymphoid tissue lymphoma treated with radiation therapy has excellent clinical outcome. J Clin Oncol, 22, pp. 4157-4164.
12. Schechter, N., Portlock, C. S. and Yahalom, J. (1998) Treatment of mucosa-associated lymphoid tissue lymphoma of the stomach with radiation alone. J Clin Oncol, 16, pp. 1916-1921.
13. Koch, P., Probst, A., Berdel, W. E., Willich, N. A., Reinartz, G. Brockmann, J. et al. (2005) Treatment results in localized primary gastric lymphoma: Data of patients registered within the german multicenter study (GIT NHL 02/96). J Clin Oncol, 23, pp. 7050-7059.
14. Hammel, P., Haioun, C., Chaumette, M. T., Gaulard, P., Divine, M. Reyes, F. et al. (1995) Efficacy of single agent chemotherapy in low grade B-cell mucosa-associated lymphoid tissue lymphoma with prominent gastric expression. J Clin Oncol, 13, pp. 2524-2529.
15. Jager, G., Neumeister, P., Brezinschek, R., Hinterleitner, T., Fiebiger, W. Penz, M. et al. (2002) Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT)-type with Cladribine (2-Chlorodeoxyadenosine): A phase II study. J Clin Oncol, 18, pp. 3872-3877.
16. Wohrer, S., Drach, J., Hejna, M., Scheithauer, W., Dirisamer, A. Puspok, A. et al. (2003) Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP). Ann Oncol, 14, pp. 1758-1761.
17. Martinelli, G., Laszlo, D., Ferreri, A. J., Pruneri, G., Ponzoni, M. Conconi, A. et al. (2005) Clinical activity of rituximab in gastric marginal zone lymphoma non-Hodgkin's lymphoma resistant to or not eligible for anti-Helicobacter pylori therapy. J Clin Oncol, 23, pp. 1979-1983.
18. Noy, A., Yahalom, J., Zaretsky, L., Brett, I. and Zelenetz, D. (2005) Gastric mucosa-associated lymphoid tissue lymphoma detected clonotypic polymerase chain reaction despite continuous pathologic remission induced by involved-field radiotherapy. J Clin Oncol, 23, pp. 3768-3772.
19. Alpen, B., Kuse, R., Parwaresch, R., Muller-Hermelink, H. K., Stolte, M. and Neubauer, A. (2004) Ongoing monoclonal B-cell proliferation is not common in gastric B-cell lymphoma after combined radiochemotherapy. J Clin Oncol, 22, pp. 3039-3045.
20. Isaacson, P. G., Muller-Hermelink, H. K., Piris, M. A., Berger, F., Nathwani, B. N. Swerdlow, S. H. et al. (2001) Extranodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue (MALT) lymphoma. Tumours of Haematopoietic and Lymphoid Tissues: World Health Organization Classification of tumours, pp. 157-160. IARC Press, Lyon
21. Rohatiner, A., d'Amore, F., Coiffier, B., Crowther, D., Gospodarowicz, M. Isaacson, P. et al. (1994) Report of a workshop convened to discuss the pathological staging classification of gastrointestinal tract lymphoma. Ann Oncol, 5, pp. 397-400.
22. Zhou, X. G., Sandve, K., Gregersen N and Hamilton-Dutoit, S. J. (1999) Detection of clonal B cells in microdissected reactive lymphoproliferations: Possible diagnostic pitfalls in PCR analysis of immunoglobulin heavy chain gene rearrangement. J Clin Pathol: Mol Pathol, 52, pp. 104-110.
23. Salar, A., Bellosillo, B., Serrano, S. and Besses, C. (2005) Persistent residual disease in t(11;18)(q21;q21) positive gastric mucosa-associated lymphoid tissue lymphoma treated with chemotherapy or rituximab. J Clin Oncol, 23, pp. 7361-7362.
24. Streubel, B., Huber, D., Wohrer, S., Chott, A. and Raderer, M. (2006) Reverse transcription-PCR for t(11;18)(q21;q21) detection in mucosa-associated lymphoid tissue lymphoma. Clin Cancer Res, 12, pp. 6028-6032.
25. Lenze, D., Greiner, A., Knorr, C., Anagnostopoulos, I., Stein, H. and Hummel, M. (2003) Receptor revision of immunoglobulin heavy chain genes in human MALT lymphomas. J Clin Pathol: Mol Pathol, 56, pp. 249-255.
26. Starostik, P., Patzner, J., Greiner, A., Schwarz, S., Kalla, J. Ott, G. et al. (2002) Gastric marginal zone B-cell lymphomas of MALT type develop along 2 distinct pathogenetic pathways. Blood, 99, pp. 3-9.
27. Farinha, P. and Gascoyne, R. (2005) Molecular pathogenesis of mucosa-associated lymphoid tissue lymphoma. J Clin Oncol, 23, pp. 6370-6378.