Antagonism of central melanin-concentrating hormone 1 receptor alleviates steatohepatitis in mice

Journal of Endocrinology

Volumn 198, Issue 2, 2008, Pages 309-315

  Ito, Makoto ^a   Gomori, Akira ^a   Suzuki, Jun ^a   Tsujioka, Shigeharu ^a   Sasaki, Minoru ^a   Matsuda, Masao ^a   Bednarek, Maria A ^b   Ito, Masahiko ^a   Ishihara, Akane ^a   Iwaasa, Hisashi ^a   MacNeil, Douglas J ^b   Kanatani, Akio ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; CYTOCHROME P450 4A; MELANIN CONCENTRATING HORMONE RECEPTOR 1 ANTAGONIST; METHIONINE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; GENE EXPRESSION; HYPERINSULINEMIA; HYPERLEPTINEMIA; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT REDUCTION;

ANIMALS; BODY WEIGHT; CHEMOKINE CCL2; COLLAGEN TYPE I; DIETARY FATS; DISEASE MODELS, ANIMAL; FATTY LIVER; GENE EXPRESSION REGULATION; INTERLEUKIN-1BETA; LIVER; MALE; MICE; MICE, INBRED C57BL; OBESITY; POLYMERASE CHAIN REACTION; RECEPTORS, PITUITARY HORMONE; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 51349089559     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-08-0087     Document Type: Article

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