Evidence of Different Pharmacokinetics Between Cyclosporine and Tacrolimus in Renal Transplant Recipients: Why Cyclosporine Is Monitored by C2 Level and Tacrolimus by Trough Level

Transplantation Proceedings

Volumn 40, Issue 7, 2008, Pages 2240-2242

  Takeuchi, H ^a   Matsuno, N ^b   Hirano, T ^a   Toraishi, T ^b   Konno, O ^b   Nakamura, Y ^b   Iwamoto, H ^b   Hama, K ^b   Unezaki, S ^a   Nagao, T ^b  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; TACROLIMUS;

ADULT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; FEMALE; GRAFT RECIPIENT; GRAFT REJECTION; HUMAN; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; PRIORITY JOURNAL;

ADULT; AREA UNDER CURVE; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG MONITORING; FEMALE; HUMANS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; TACROLIMUS;

EID: 51249105570     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.07.094     Document Type: Article

References (2)

1. Wang C.H., Ko W.J., Chou N.K., et al. Therapeutic drug monitoring of tacrolimus in cardiac transplant recipients: a comparison with cyclosporine Neoral. Transplant Proc 36 (2004) 2386
2. Mahalati K., Belitsky P., Sketris I., et al. Neoral monitoring by simplified sparse sampling area under the concentration-time curve. Transplantation 68 (1999) 55