Neural bases of emotional processing in pediatric bipolar disorder

Expert Review of Neurotherapeutics

Volumn 8, Issue 9, 2008, Pages 1381-1387

  Pavuluri, Mani N ^a   Passarotti, Alessandra ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Bipolar disorder; Children; Diffusion tensor imaging; Emotion; Functional MRI; Magnetic resonance spectroscopy; MRI

Indexed keywords

LITHIUM; VALPROATE SEMISODIUM;

AMYGDALOID NUCLEUS; ANISOTROPY; AUTOREGULATION; BASAL GANGLION; BIPOLAR DISORDER; BRAIN; BRAIN DYSFUNCTION; BRAIN FUNCTION; BRAIN MAPPING; BRAIN REGION; BRAIN SIZE; CEREBELLUM; COGNITION; CORPUS CALLOSUM; CORPUS STRIATUM; DIFFUSION TENSOR IMAGING; DISEASE ASSOCIATION; DISEASE DURATION; EMOTION; FACIAL EXPRESSION; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; LIMBIC CORTEX; NERVE CELL NETWORK; OCCIPITAL CORTEX; PHENOTYPE; PREFRONTAL CORTEX; REVIEW; VERBAL MEMORY; WORKING MEMORY;

BIPOLAR DISORDER; BRAIN; CHILD; EMOTIONS; HUMANS; MAGNETIC RESONANCE IMAGING; NEURAL PATHWAYS;

EID: 51149119746     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/14737175.8.9.1381     Document Type: Review

References (44)

1. Pavuluri MN, Bishop JR. Pediatric bipolar disorder: translation of research findings to clinical practice. Curr. Med. Lit. Pediatr. 18, 1-12 (2007).
2. Friedman L, Findling RL, Kenny JT et al. An MRI study of adolescent patients with either schizophrenia or bipolar disorder as compared with healthy control subjects. Biol. Psychiatry 46, 78-88 (1999).
3. DelBello MP, Zimmerman ME, Mills NP, Getz GE, Strakowski SM. Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorder. Bipolar Disord. 6, 43-52 (2004).
4. Frazier JA, Chiu S, Breeze JL et al. Structural brain magnetic resonance imaging of limbic and thalamic volumes in pediatric bipolar disorder. Am. J. Psychiatry 162, 1256-1265 (2005).
5. Pearlson GD, Barta PE, Powers RE et al. Medial and superior temporal gyral volumes and cerebral asymmetry in schizophrenia versus bipolar disorder. Biol. Psychiatry 41, 1-14 (1997).
6. Botteron KN, Figiel GS, Wetzel MW, Hudziak J, VanEerdewegh M. MRI abnormalities in adolescent bipolar affective disorder. J. Am. Acad. Child Adolesc. Psychiatry 31, 258-261 (1992).
7. Chen HH, Nicoletti MA, Hatch JP et al. Abnormal left superior temporal gyrus volumes in children and adolescents with bipolar disorder: a magnetic resonance imaging study. Neurosci. Lett. 363, 65-68 (2004).
8. Frazier JA, Breeze JL, Makris N et al. Cortical gray matter differences identified by structural magnetic resonance imaging in pediatric bipolar disorder. Bipolar Disord. 7, 555-569 (2005).
9. Wilke M, Kowatch RA, DelBello MP, Mills NP, Holland SK. Voxel-based morphometry in adolescents with bipolar disorder: first results. Psychiatry Res. 131, 57-69 (2004).
10. Dickstein DP, Milham MP, Nugent AC et al. Frontotemporal alterations in pediatric bipolar disorder: results of a voxel-based morphometry study. Arch. Gen. Psychiatry 62, 734-741 (2005).
11. Sperry RW. Mental unity following surgical disconnection of the cerebral hemispheres. Harvey Lect. 62, 293-323, 293-323 (1966).
12. de Lacoste MC, Kirkpatrick JB, Ross ED. Topography of the human corpus callosum. J. Neuropathol. Exp. Neurol. 44, 578-591 (1985).
13. Yasar AS, Monkul ES, Sassi RB et al. MRI study of corpus callosum in children and adolescents with bipolar disorder. Psychiatry Res. 146, 83-85 (2006).
14. Blumberg HP, Kaufman J, Martin A et al. Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder. Arch. Gen. Psychiatry 60, 1201-1208 (2003).
15. Singh MK, DelBello MP, Adler CM, Stanford KE, Strakowski SM. Neuroanatomical characterization of child offspring of bipolar parents. J. Am. Acad. Child Adolesc. Psychiatry 47, 526-531 (2008).
16. Strakowski SM, Adler CM, DelBello MP. Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder? Bipolar Disord. 4, 80-88 (2002).
17. Strakowski SM, DelBello MP, Zimmerman ME et al. Ventricular and periventricular structural volumes in first-versus multiple-episode bipolar disorder. Am. J. Psychiatry 159, 1841-1847 (2002).
18. Schmahmann JD, Doyon J, Toga AW, Petrides M, Evans AC. MRI Atlas of the Human Cerebellum. Academic Press, CA, USA (2000).
19. DelBello MP, Strakowski SM, Zimmerman ME, Hawkins JM, Sax KW. MRI analysis of the cerebellum in bipolar disorder: a pilot study. Neuropsychopharmacol. 21, 63-68 (1999).
20. Mills NP, DelBello MP, Adler CM, Strakowski SM. MRI analysis of cerebellar vermal abnormalities in bipolar disorder. Am. J. Psychiatry 162, 1530-1532 (2005).
21. Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 161, 401-407 (1986).
22. Beaulieu C. The basis of anisotropic water diffusion in the nervous system - a technical review. NMR Biomed. 15, 435-455 (2002).
23. Adler CM, Holland SK, Schmithorst V et al. Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study. Bipolar Disord. 6, 197-203 (2004).
24. Beyer JL, Taylor WD, MacFall JR et al. Cortical white matter microstructural abnormalities in bipolar disorder. Neuropsychopharmacol. 30, 2225-2229 (2005).
25. Yurgelun-Todd DA, Silveri MM, Gruber SA, Rohan ML, Pimentel PJ. White matter abnormalities observed in bipolar disorder: a diffusion tensor imaging study. Bipolar Disord. 9, 504-512 (2007).
26. Adler CM, Adams J, DelBello MP et al. Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study. Am. J. Psychiatry 163, 322-324 (2006).
27. Pavuluri M, Shuohui CY, Girish S et al. Diffusion Tensor imaging of five white fiber tracts in pediatric bipolar disorder. Bipolar Disord. (In Press).
28. Dickstein DP, Treland JE, Snow J et al. Neuropsychological performance in pediatric bipolar disorder. Biol. Psychiatry 55, 32-39 (2004).
29. Yang S, Pavuluri MN, O'Connor MM et al. A diffusion tensor imaging study of pediatric bipolar disorder. J. Magn. Reson. Imaging (In Press).
30. Pavuluri MN, Schenkel LS, Aryal S et al. Neurocognitive function in unmedicated manic and medicated euthymic pediatric bipolar patients. Am. J. Psychiatry 163, 286-293 (2006).
31. Dickstein DP, Nelson EE, McClure EB et al. Cognitive flexibility in phenotypes of pediatric bipolar disorder. J. Am. Acad. Child Adolesc. Psychiatry 46, 341-355 (2007).
32. McClure EB, Pope K, Hoberman A, Pine DS, Liebenluft E. Facial expression recognition in adolescents with mood and anxiety disorders. Am. J. Psychiatry 160, 1-3 (2003).
33. Schenkel LS, Pavuluri MN, Harral EM, Sweeney JA. Facial emotion processing in medicated and unmedicated patients with pediatric bipolar disorder. J. Am. Acad. Child Adolesc. Psychiatry 46, 1070-1079 (2007).
34. Chang K, Adleman NE, Dienes K, Simeonova DI, Menon V, Reiss A. Anomalous prefrontal-subcortical activation in familial pediatric bipolar disorder: a functional magnetic resonance imaging investigation. Arch. Gen. Psychiatry 61, 781-792 (2004).
35. Blumberg HP, Martin A, Kaufman J et al. Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI. Am. J. Psychiatry 160, 1345-1347 (2003).
36. Pavuluri MN, O'Connor MM, Harral EM, Sweeney JA. Affective neural circuitry during facial emotion processing in pediatric bipolar disorder. Biol. Psychiatry 62, 158-167 (2007).
37. Rich BA, Vinton DT, Roberson-Nay R et al. Limbic hyperactivation during processing of neutral facial expressions in children with bipolar disorder. Proc. Natl Acad. Sci. USA 103, 8900-8905 (2006).
38. Haxby JV, Hoffman EA, Gobbini MI. The distributed human neural system for face perception. Trends Cogn. Sci. 4, 223-233 (2000).
39. Pessoa L, McKenna M, Gutierrez E, Ungerleider LG. Neural processing of emotional faces requires attention. Proc. Natl Acad. Sci. USA 99, 11458-11463 (2002).
40. Kesler-West ML, Andersen AH, Smith CD et al. Neural substrates of facial emotion processing using fMRI. Cogn. Brain Res. 11, 213-226 (2001).
41. Pavuluri MN, O'Connor MM, Harral EM, Sweeney JA. An fMRI study of the interface between affective and cognitive neural circuitry in pediatric bipolar disorder. Psychiatry Res. 162, 244-255 (2008).
42. DelBello MP, Soutullo CA, Hendricks W, Niemeier RT, McElroy SL, Strakowski SM. Prior stimulant treatment in adolescents with bipolar disorder: association with age at onset. Bipolar Disord. 3, 53-57 (2001).
43. Pavuluri MN, Birmaher B, Naylor MW. Pediatric bipolar disorder: a review of the past 10 years. J. Am. Acad. Child Adolesc. Psychiatry 44, 846-871 (2005).
44. Pavuluri MN, Sweeney JA. The new focus on brain function in child psychiatry research. J. Am. Acad. Child Adolesc. Psychiatry (In Press).