메뉴 건너뛰기




Volumn 4, Issue 9, 2008, Pages 464-472

Update on the management of lupus nephritis: Let the treatment fit the patient

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; GLUCOCORTICOID; HYDROXYCHLOROQUINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RITUXIMAB; TACROLIMUS; VITAMIN D;

EID: 51149105272     PISSN: 17458382     EISSN: 17458390     Source Type: Journal    
DOI: 10.1038/ncprheum0896     Document Type: Review
Times cited : (38)

References (43)
  • 1
    • 0026767866 scopus 로고
    • Controlled trial of pulse methylprednisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis
    • Boumpas DT et al. (1992) Controlled trial of pulse methylprednisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis. Lancet 340: 741-745
    • (1992) Lancet , vol.340 , pp. 741-745
    • Boumpas, D.T.1
  • 2
    • 0030268581 scopus 로고    scopus 로고
    • Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial
    • Gourley MF et al. (1996) Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial. Ann Intern Med 125: 549-557
    • (1996) Ann Intern Med , vol.125 , pp. 549-557
    • Gourley, M.F.1
  • 3
    • 0035928643 scopus 로고    scopus 로고
    • Combination therapy with pulse cyclophosphamide plus pulse methylpredinisolone improves long-term renal outcome without adding toxicity in patients with lupus nephritis
    • Illei GG et al. (2001) Combination therapy with pulse cyclophosphamide plus pulse methylpredinisolone improves long-term renal outcome without adding toxicity in patients with lupus nephritis. Ann Intern Med 135:248-257
    • (2001) Ann Intern Med , vol.135 , pp. 248-257
    • Illei, G.G.1
  • 4
    • 0027380153 scopus 로고
    • Risk for sustained amenorrhea in patients with systemic lupus erythematosus receiving intermittent pulse cyclophosphamide therapy
    • Boumpas DT et al. (1993) Risk for sustained amenorrhea in patients with systemic lupus erythematosus receiving intermittent pulse cyclophosphamide therapy. Ann Intern Med 119: 366-369
    • (1993) Ann Intern Med , vol.119 , pp. 366-369
    • Boumpas, D.T.1
  • 5
    • 10444275010 scopus 로고    scopus 로고
    • Early response to immunosuppressive therapy predicts good renal outcome in lupus nephntis: Lessons from long-term followup of patients in the Euro-Lupus Nephritis Trial
    • Houssiau FA et al. (2004) Early response to immunosuppressive therapy predicts good renal outcome in lupus nephntis: Lessons from long-term followup of patients in the Euro-Lupus Nephritis Trial. Arthritis Rheum 50: 3934-3940
    • (2004) Arthritis Rheum , vol.50 , pp. 3934-3940
    • Houssiau, F.A.1
  • 6
    • 33748998203 scopus 로고    scopus 로고
    • Optimum therapeutic approaches for lupus nephritis: What therapy and for whom?
    • Boumpas DT et al. (2005) Optimum therapeutic approaches for lupus nephritis: What therapy and for whom? Nat Clin Pract Rheumatol 1: 22-30
    • (2005) Nat Clin Pract Rheumatol , vol.1 , pp. 22-30
    • Boumpas, D.T.1
  • 7
    • 33747082349 scopus 로고    scopus 로고
    • Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial
    • Grootscholten C et al. (2006) Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial. Kidney Int 70: 732-742
    • (2006) Kidney Int , vol.70 , pp. 732-742
    • Grootscholten, C.1
  • 8
    • 33947114890 scopus 로고    scopus 로고
    • Treatment with cyclophosphamide delays the progression of chronic lesions more effectively than does treatment with azathioprine plus methylprednisolone in patients with proliferative lupus nephritis
    • Grootscholten C et al. (2007) Treatment with cyclophosphamide delays the progression of chronic lesions more effectively than does treatment with azathioprine plus methylprednisolone in patients with proliferative lupus nephritis. Arthritis Rheum 56: 924-937
    • (2007) Arthritis Rheum , vol.56 , pp. 924-937
    • Grootscholten, C.1
  • 9
    • 33645241849 scopus 로고    scopus 로고
    • Long-term outcome of diffuse proliferative lupus glomerulonephritis treated with cyclophosphamide
    • Mok CC et al. (2006) Long-term outcome of diffuse proliferative lupus glomerulonephritis treated with cyclophosphamide. Am J Med 119: E25-e33
    • (2006) Am J Med , vol.119
    • Mok, C.C.1
  • 10
    • 33847193118 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis
    • Moore RA and Derry S (2006) Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis. Arthritis Res Ther 8: 1-10
    • (2006) Arthritis Res Ther , vol.8 , pp. 1-10
    • Moore, R.A.1    Derry, S.2
  • 11
    • 34548845067 scopus 로고    scopus 로고
    • Mycophenolate mofetil for induction therapy of lupus nephritis: A systematic review and meta-analysis
    • Walsh M et al. (2007) Mycophenolate mofetil for induction therapy of lupus nephritis: A systematic review and meta-analysis. Clin J Am Soc Nephrol 5: 968-975
    • (2007) Clin J Am Soc Nephrol , vol.5 , pp. 968-975
    • Walsh, M.1
  • 12
    • 34547830199 scopus 로고    scopus 로고
    • Mycophenolate mofetil in induction and maintenance therapy of severe lupus nephritis: A meta-analysis of randomized controlled trials
    • Zhu B et al. (2007) Mycophenolate mofetil in induction and maintenance therapy of severe lupus nephritis: A meta-analysis of randomized controlled trials. Nephrol Dial Transplant 22 1933-1942
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 1933-1942
    • Zhu, B.1
  • 14
    • 63649165262 scopus 로고    scopus 로고
    • Mycophenolate mofetil and intravenous cyclophosphamide in the Aspreva Lupus Management Study (ALMS): Efficacy by racial group. Presented at the
    • Boston, MA
    • Ginzler EM et al. (2007) Mycophenolate mofetil and intravenous cyclophosphamide in the Aspreva Lupus Management Study (ALMS): Efficacy by racial group. Presented at the. American College of Rheumatology Annual Meeting, 2007, Boston, MA [www.rheumatology.org]
    • (2007) American College of Rheumatology Annual Meeting
    • Ginzler, E.M.1
  • 15
    • 0029901773 scopus 로고    scopus 로고
    • Nephritic flares are predictors of bad long-term renal outcome in lupus nephritis
    • Moroni G et al. (1996) "Nephritic flares" are predictors of bad long-term renal outcome in lupus nephritis. Kidney Int 50: 2047-2053
    • (1996) Kidney Int , vol.50 , pp. 2047-2053
    • Moroni, G.1
  • 16
    • 0036222879 scopus 로고    scopus 로고
    • Renal flares are common in patients with severe proliferative lupus nephritis treated with pulse immunosuppressive therapy: Long-term followup of a cohort of 145 patients participating in randomized controlled studies
    • Illei GG et al. (2002) Renal flares are common in patients with severe proliferative lupus nephritis treated with pulse immunosuppressive therapy: Long-term followup of a cohort of 145 patients participating in randomized controlled studies. Arthritis Rheum 46:995-1002
    • (2002) Arthritis Rheum , vol.46 , pp. 995-1002
    • Illei, G.G.1
  • 17
    • 15944410008 scopus 로고    scopus 로고
    • Long-term outcome of patients with diffuse proliferative lupus nephritis treated with prednisolone and oral cyclophosphamide followed by azathioprine
    • Chan TM et al. (2005) Long-term outcome of patients with diffuse proliferative lupus nephritis treated with prednisolone and oral cyclophosphamide followed by azathioprine. Lupus 14:265-272
    • (2005) Lupus , vol.14 , pp. 265-272
    • Chan, T.M.1
  • 18
    • 34548454046 scopus 로고    scopus 로고
    • A randomized pilot trial comparing cyclosporine and azathioprine for maintenance therapy in diffuse lupus nephritis over four years
    • Moroni G et al. (2006) A randomized pilot trial comparing cyclosporine and azathioprine for maintenance therapy in diffuse lupus nephritis over four years. Clin J Am Soc Nephrol 1: 925-932
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 925-932
    • Moroni, G.1
  • 19
    • 20444466207 scopus 로고    scopus 로고
    • Long-term study of mycophenolate mofetil as continuous induction and maintenance treatment for diffuse proliferative lupus nephritis
    • Chan TM et al. (2005) Long-term study of mycophenolate mofetil as continuous induction and maintenance treatment for diffuse proliferative lupus nephritis. J Am Soc Nephrol 16: 1076-1084
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1076-1084
    • Chan, T.M.1
  • 20
    • 1442355581 scopus 로고    scopus 로고
    • Sequential therapies for proliferative lupus nephritis
    • Contreras G et al. (2004) Sequential therapies for proliferative lupus nephritis. N Engl J Med 350: 971-980
    • (2004) N Engl J Med , vol.350 , pp. 971-980
    • Contreras, G.1
  • 21
    • 21144438589 scopus 로고    scopus 로고
    • Tolerance and short term efficacy of rituximab in 43 patients with systemic autoimmune diseases
    • Gottenberg JE et al. (2005) Tolerance and short term efficacy of rituximab in 43 patients with systemic autoimmune diseases. Ann Rheum Dis 64: 913-920
    • (2005) Ann Rheum Dis , vol.64 , pp. 913-920
    • Gottenberg, J.E.1
  • 22
    • 34247246405 scopus 로고    scopus 로고
    • Histopathologic and clinical outcome of rituximab treatment in patients with cyclophosphamide-resistant proliferative lupus nephritis
    • Gunnarsson I et al. (2007) Histopathologic and clinical outcome of rituximab treatment in patients with cyclophosphamide-resistant proliferative lupus nephritis. Arthritis Rheum 56: 1263-1272
    • (2007) Arthritis Rheum , vol.56 , pp. 1263-1272
    • Gunnarsson, I.1
  • 23
    • 4043179907 scopus 로고    scopus 로고
    • B cell depletion as a novel treatment for systemic lupus erythematosus: A phase I/II dose-escalation trial of rituximab
    • Looney RJ et al. (2004) B cell depletion as a novel treatment for systemic lupus erythematosus: A phase I/II dose-escalation trial of rituximab. Arthritis Rheum 50: 2580-2589
    • (2004) Arthritis Rheum , vol.50 , pp. 2580-2589
    • Looney, R.J.1
  • 24
    • 34548151122 scopus 로고    scopus 로고
    • B cell depletion therapy in systemic lupus erythematosus: Long-term follow-up and predictors of response
    • Ng KP et al. (2007) B cell depletion therapy in systemic lupus erythematosus: Long-term follow-up and predictors of response. Ann Rheum Dis 66: 1259-1262
    • (2007) Ann Rheum Dis , vol.66 , pp. 1259-1262
    • Ng, K.P.1
  • 25
    • 13444252282 scopus 로고    scopus 로고
    • Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: An open-label trial
    • Sfikakis PP et al. (2005) Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: An open-label trial. Arthritis Rheum 52: 501-513
    • (2005) Arthritis Rheum , vol.52 , pp. 501-513
    • Sfikakis, P.P.1
  • 26
    • 33749331884 scopus 로고    scopus 로고
    • Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re-treatment
    • Smith KG et al. (2006) Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re-treatment. Arthritis Rheum 54: 2970-2982
    • (2006) Arthritis Rheum , vol.54 , pp. 2970-2982
    • Smith, K.G.1
  • 27
    • 34250631349 scopus 로고    scopus 로고
    • A multicenter phase I/II trial of rituximab for refractory systemic lupus erythematosus
    • Tanaka Y et al. (2007) A multicenter phase I/II trial of rituximab for refractory systemic lupus erythematosus. Mod Rheumatol 17 191-197
    • (2007) Mod Rheumatol , vol.17 , pp. 191-197
    • Tanaka, Y.1
  • 28
    • 70350525210 scopus 로고    scopus 로고
    • Clinical and immunological effects of rituximab in patients with lupus nephritis refractory to conventional therapy: A pilot study
    • Vigna-Perez M et al. (2006) Clinical and immunological effects of rituximab in patients with lupus nephritis refractory to conventional therapy: A pilot study. Arthritis Res Ther 8: R83
    • (2006) Arthritis Res Ther , vol.8
    • Vigna-Perez, M.1
  • 29
    • 51149123999 scopus 로고    scopus 로고
    • Genentech Inc. website, accessed 17 July 2008
    • Genentech Inc. website [http://www.gene.com/gene/news] (accessed 17 July 2008)
  • 30
    • 51149115196 scopus 로고    scopus 로고
    • A study to evaluate the efficacy and safety of rituximab in patients with severe systemic lupus erythematosus EXPLORER, accessed 17 July 2008
    • A study to evaluate the efficacy and safety of rituximab in patients with severe systemic lupus erythematosus (EXPLORER) [http://clinicaltrials.gov/ct/show/NCT00137969] (accessed 17 July 2008)
  • 31
    • 51149094884 scopus 로고    scopus 로고
    • Study to evaluate the efficacy and safety of rituximab in subjects with ISN/RPS class III or IV lupus nephritis LUNAR, accessed 17 July 2008
    • Study to evaluate the efficacy and safety of rituximab in subjects with ISN/RPS class III or IV lupus nephritis (LUNAR) [http://clinicaltrials.gov/ct/show/NCT00282347] (accessed 17 July 2008)
  • 32
    • 34247247141 scopus 로고    scopus 로고
    • Prospective study of low-dose cyclosporine A in patients with refractory lupus nephritis
    • Ogawa H et al. (2007) Prospective study of low-dose cyclosporine A in patients with refractory lupus nephritis. Mod Rheumatol 17 92-97
    • (2007) Mod Rheumatol , vol.17 , pp. 92-97
    • Ogawa, H.1
  • 33
    • 26944455632 scopus 로고    scopus 로고
    • Tacrolimus for induction therapy of diffuse proliferative lupus nephritis: An open-labeled pilot study
    • Mok CC et al. (2005) Tacrolimus for induction therapy of diffuse proliferative lupus nephritis: An open-labeled pilot study. Kidney Int 68: 813-817
    • (2005) Kidney Int , vol.68 , pp. 813-817
    • Mok, C.C.1
  • 34
    • 0742305474 scopus 로고    scopus 로고
    • Treatment of pure membranous lupus nephropathy with prednisone and azathioprine: An open-label trial
    • Mok CC et al. (2004) Treatment of pure membranous lupus nephropathy with prednisone and azathioprine: An open-label trial. Am J Kidney Dis 43:269-276
    • (2004) Am J Kidney Dis , vol.43 , pp. 269-276
    • Mok, C.C.1
  • 35
    • 0031953377 scopus 로고    scopus 로고
    • Treatment of membranous lupus nephritis
    • Moroni G et al. (1998) Treatment of membranous lupus nephritis. Am J Kidney Dis 31: 681-686
    • (1998) Am J Kidney Dis , vol.31 , pp. 681-686
    • Moroni, G.1
  • 36
    • 20944441467 scopus 로고    scopus 로고
    • Mycophenolate therapy of SLE membranous nephropathy
    • Spetie DN et al. (2004) Mycophenolate therapy of SLE membranous nephropathy. Kidney Int 66: 2411-2415
    • (2004) Kidney Int , vol.66 , pp. 2411-2415
    • Spetie, D.N.1
  • 37
    • 50849154422 scopus 로고    scopus 로고
    • Lupus membranous nephropathy: Controlled trial of prednisone, pulse cyclophosphamide and cyclosporine A [abstract]
    • Austin H et al. (2004) Lupus membranous nephropathy: Controlled trial of prednisone, pulse cyclophosphamide and cyclosporine A [abstract]. J Am Soc Nephrol 15: 54A
    • (2004) J Am Soc Nephrol , vol.15
    • Austin, H.1
  • 38
    • 1542299598 scopus 로고    scopus 로고
    • Lupus nephritis: Treatment with mycophenolate mofetil
    • Kapitsinou PP et al. (2004) Lupus nephritis: Treatment with mycophenolate mofetil. Rheumatology (Oxford) 43:377-380
    • (2004) Rheumatology (Oxford) , vol.43 , pp. 377-380
    • Kapitsinou, P.P.1
  • 39
    • 27144556088 scopus 로고    scopus 로고
    • Reduction of proteinuria with mycophenolate mofetil in predominantly membranous lupus nephropathy
    • Karim MY et al. (2005) Reduction of proteinuria with mycophenolate mofetil in predominantly membranous lupus nephropathy. Rheumatology (Oxford) 44: 1317-1321
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 1317-1321
    • Karim, M.Y.1
  • 40
    • 33748997049 scopus 로고    scopus 로고
    • Mycophenolate mofetil is effective in reducing lupus glomerulonephritis proteinuria
    • Borba EF et al. (2006) Mycophenolate mofetil is effective in reducing lupus glomerulonephritis proteinuria. Rheumatol Int 12 1078-1083
    • (2006) Rheumatol Int , vol.12 , pp. 1078-1083
    • Borba, E.F.1
  • 41
    • 33846613753 scopus 로고    scopus 로고
    • A pilot study on tacrolimus treatment in membranous or quiescent lupus nephritis with proteinuria resistant to angiotensin inhibition or blockade
    • Tse KC et al. (2007) A pilot study on tacrolimus treatment in membranous or quiescent lupus nephritis with proteinuria resistant to angiotensin inhibition or blockade. Lupus 16:46-51
    • (2007) Lupus , vol.16 , pp. 46-51
    • Tse, K.C.1
  • 42
    • 19544382185 scopus 로고    scopus 로고
    • Premature atherosclerosis in systemic lupus erythematosus
    • Nikpour M et al. (2005) Premature atherosclerosis in systemic lupus erythematosus. Rheum Dis Clin North Am 31: 329-354
    • (2005) Rheum Dis Clin North Am , vol.31 , pp. 329-354
    • Nikpour, M.1
  • 43
    • 38749089852 scopus 로고    scopus 로고
    • EULAR recommendations for the management of systemic lupus erytematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics
    • Bertsias GK et al. (2008) EULAR recommendations for the management of systemic lupus erytematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics. Ann Rheum Dis 67:195-205
    • (2008) Ann Rheum Dis , vol.67 , pp. 195-205
    • Bertsias, G.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.