Optimization of γ-aminobutyric acid liquid fermentation conditions and its fed-batch fermentation

Gao Xiao Hua Xue Gong Cheng Xue Bao/Journal of Chemical Engineering of Chinese Universities

Volumn 22, Issue 4, 2008, Pages 618-623

  Huang, Jun ^a,b   Mei, Le He ^a   Sheng, Qing ^b   Xu, Jing ^c   Wu, Hui ^c  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c Hangzhou Huadong Medicine Group Co Ltd   (China)

Author keywords

aminobutyric acid; Batch fermentation; Cultivation conditions; Fed batch fermentation; PH control

Indexed keywords

ACIDS; AMINO ACIDS; BIOCHEMICAL ENGINEERING;

AMINOBUTYRIC ACIDS; BATCH FERMENTATION; CULTIVATION CONDITIONS; FED-BATCH FERMENTATION; PH CONTROL;

PH EFFECTS;

EID: 51149097914     PISSN: 10039015     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Krnjevic K. Chemical nature of synaptic transmission in vertebrates[J]. Physiol Rev, 1974, 54(2): 419-540.
2. Okada T, Sugishita T, Murakami T. Effect of the defatted rice germ enriched with GABA for sleeplessness, depression, autonomic disorder by oral administration.[J]. Nippon Shokuhin Kagaku Kaishi, 2000, 47(8): 596-603.
3. Defeudis F V. γ-Aminobutyric acid and cardiovascular function[J]. Experientia, 1983, 39(8): 845-849.
4. Roldan E R S, Murase T, Shi Q X. Exocytosis in spermatozoa in response to progesterone and zona pellucida[J]. Science, 1994, 266(5190): 1578-1581.
5. Kroschwitz, Jacqueline I. Kirk-othmer Encyclopedia of Chemical Technology[M]. USA: Wiley Interscience. 1981, p766-777.
6. Takahashi T, Furukawa A, Hara S et al. Isolation and characterization of sake yeast mutants deficient in γ-aminobutyric acid utilization in sake brewing[J]. J Biosci Bioeng, 2004, 97(6): 412-418.
7. Komatsuzaki N, Shima J, Kawamoto S et al. Production of γ-aminobutyric acid (GABA) by Lactobacillus paracasei isolated from traditional fermented foods[J]. Food Microbiol, 2005, 22: 497-504.
8. XU Jian-jun, JIANG Bo, XU Shi-ying. Screening of lactic acid bacteria for biosynthesis of γ-aminobutyric acid[J]. Food Science and Technology, 2002, 10: 7-8.
9. LIU Qing, YAO Hui-yuan, ZHANG Hui. Studies on screening for γ-amino butyric acid producer and optimization of fermentation conditions[J]. Amino Acids and Biotic resources, 2004, 26(1): 40-43.
10. CUI Xiao-jun, JIANG Bo, FENG Biao. Optimization of fermentation conditions for GABA (γ-aminobutyric acid) production by Lactobacillus SK005[J]. Food Research and Development, 2005, 26(6): 64-69.
11. XIA Jiang, MEI Le-he, HUANG Jun et al. Optimization of fermentation process for the production of γ-aminobutyric acid by Lactobacillus brevis based on artificial neural network and particle swarm optimization[J]. J Chem Eng of Chinese Univ, 2007, 21(6): 997-1001.
12. Miller G L. Use of 3, 5-dinitrosalicylic acid reagent for determination of reducing sugars[J]. Anal Chem, 1959, 31(3), 426-428.
13. DENG Fu-hua, MEI Le-he, HUANG Jun et al. Determination of γ-aminobutyric acid in fermentation broth by high performance liquid chromatography[J]. Journal of Materials Science and Engineering, 2005, 23(Suppl.): 100-102.
14. Kumar S, Punekar N S, SatyaNarayan V et al. Metabolic fate of glutamate and evaluation of flux through the 4-aminobutyrate (GABA) shunt in Aspergillus niger[J]. Biotechnol Bioeng 2000, 67(5): 575-584.
15. Van Cauwenberghe O R, Shelp B J. Biochemical characterization of partially purified gaba: pyruvate transaminase from Nicotiana tabacum[J]. Phytochemistry, 1999, 52(4): 575-581.
16. Higuchi T, Hayashi H, Abe K. Exchange of glutamate and gamma-aminobutyrate in a Lactobacillus strain[J]. J Bacteriol, 1997, 179 (10): 3362-3364.
17. Ueno H. Enzymatic and structural aspects on glutamate decarboxylase[J]. J Mol Catal B: Enzym, 2000, 10(1-3): 67-79.