Evaluation of triple anti-platelet therapy by modified thrombelastography in patients with acute coronary syndrome

Chinese Medical Journal

Volumn 121, Issue 9, 2008, Pages 850-852

  Ren, Yi Hong ^a   Yang, Ting Shu ^a   Wang, Yu ^a   Gai, Lu Yue ^a   Liu, Hong Bin ^a   Chen, Lian ^a   Wang, Hong Ye ^a   Wang, Chun Ya ^a   Xu, Xiu Li ^a   Jin, Jing ^a   Xin, You Hong ^a   Li, Rong Bin ^a   Li, Hai Yan ^a   Lin, Lin ^a   Liu, Chun Xue ^a  

^a The First Affiliated Hospital of General Hospital of the Chinese People's Liberation Army   (China)

Author keywords

Acute coronary syndrome; Modified thrombelastography; Platelet

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CITRIC ACID; CLOPIDOGREL; HEPARIN; TIROFIBAN; DRUG DERIVATIVE; TICLOPIDINE; TYROSINE;

ACUTE CORONARY SYNDROME; ACUTE HEART INFARCTION; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CELL ACTIVITY; CLINICAL ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG WITHDRAWAL; HUMAN; LOADING DRUG DOSE; OBSERVATIONAL STUDY; PERCUTANEOUS CORONARY INTERVENTION; SINGLE DRUG DOSE; THROMBOCYTE; THROMBOELASTOGRAPHY; TREATMENT DURATION; TRANSLUMINAL CORONARY ANGIOPLASTY;

ACUTE CORONARY SYNDROME; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ASPIRIN; HUMANS; PLATELET AGGREGATION INHIBITORS; THROMBELASTOGRAPHY; TICLOPIDINE; TYROSINE;

EID: 51149088529     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200805010-00018     Document Type: Article

References (9)

1. Tantry US, Bliden KP, Gurbel PA. Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachadonic acid stimulation. J Am Coll Cardiol 2005; 46: 1705-1709.
2. Agarwal S, Coakely M, Mallett S, Riddell A, Mallett S. Quantifying the effect of antiplatelet therapy-A comparison of the platelet function analyzer (PFA-100®) and modified thromboelastography (mTEG®) with light transmission platelet aggregometry. Anesthesiology 2006; 105:676-683.
3. Bliden KP, DiChiara J, Tantry US, Bassi AK, Chaganti SK, Gurbel PA. Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: is the current antiplatelet therapy adequate? J Am Coll Cardiol 2007; 49: 657-666.
4. Hobson AR, Agarwala RA, Swallow RA, Dawkins KD, Curzen NP. Thrombelastograppy: current clinical applications and its potential role in interventional cardiology. Platelets 2006; 17: 509-518.
5. Gurbel PA, Bliden KP, DiChiara J, Newcomer J, Weng W, Neerchal NK, et al. Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study. Circulation 2007; 115: 3156-3164.
6. Lev El, Patel RT, Maresh KJ, Guthikonda S, Granada J, Delao T, et al. Aspirin and clopidogrel drug response in patients undergoing percutaneous intervention: the role of dual drug resistance. J Am Coll Cardiol 2006; 47: 27-33.
7. Wenaweser P, Dorffler MJ, Imboden K, Windecker S, Togni M, Meier B, et al. Stent thrombosis is associated with an impaired response to antiplatelet therapy. J Am Coll Cardiol 2005; 45: 1748-1752.
8. Male C, Koren D, Eichelberger B, Kaufmann K, Panzer S. Monitoring survival and function of transfused platelets in Glanzmann thrombasthenia by flow cytometry and thrombelastography. Vox Sanguinis 2006; 91: 174-177.
9. McGrath DJ, Ceboni E, Frumento RJ, Hirsh AL, Bennett GE. Thrombelastography maximum amplitude predicts post-operative thrombotic complications including myocardial infarction. Anesth Analg 2005; 100: 1576-1583.