Severe acute respiratory syndrome coronavirus elicits a weak interferon response compared to traditional interferon-inducing viruses

Intervirology

Volumn 51, Issue 4, 2008, Pages 217-223

  Scagnolari, Carolina ^a   Trombetti, Simona ^a   Cicetti, Simona ^a   Antonelli, Silvia ^a   Selvaggi, Carla ^a   Perrone, Lorena ^c   Visca, Michela ^b   Romano, Sara ^b   Antonelli, Guido ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SANDRO PERTINI HOSPITAL   (Italy)

^c INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

Interferon; Interferon ; Interferon subtypes; Interferon ; Interferon ; SARS CoV

Indexed keywords

ALPHA INTERFERON; ALPHA1 INTERFERON; ALPHA10 INTERFERON; ALPHA13 INTERFERON; ALPHA17 INTERFERON; ALPHA21 INTERFERON; ALPHA5 INTERFERON; ALPHA8 INTERFERON; BETA INTERFERON; GAMMA INTERFERON; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CYTOKINE PRODUCTION; GENE EXPRESSION PROFILING; HOST RESISTANCE; HUMAN; HUMAN CELL; NEWCASTLE DISEASE PARAMYXOVIRUS; NONHUMAN; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SARS CORONAVIRUS; SUPERNATANT; VESICULAR STOMATITIS VIRUS; VIRUS INFECTION;

CELLS, CULTURED; GENE EXPRESSION PROFILING; HUMANS; INTERFERONS; LEUKOCYTES, MONONUCLEAR; NEWCASTLE DISEASE VIRUS; SARS VIRUS; VESICULOVIRUS;

NEWCASTLE DISEASE VIRUS; SARS CORONAVIRUS; VESICULAR STOMATITIS VIRUS;

EID: 51049118830     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000154258     Document Type: Article

References (34)

1. Satija N, Lal SK: The molecular biology of SARS coronavirus. Ann NY Acad Sci 2007;1102:26-38.
2. Chelbi-Alix MK, Wietzerbin J: Interferon, a growing cytokine family: 50 years of interferon research. Biochimie 2007;89:713-718.
3. Pitkäranta A, Hovi T: Induction of interferon in human leukocyte cultures by natural pathogenic respiratory viruses. J Interferon Res 1993;13:423-426.
4. Weber F, Haller O: Viral suppression of the interferon system. Biochimie 2007;89:836-842.
5. Vicenzi E, Canducci F, Pinna D, Mancini N, Carletti S, Lazzarin A, Bordignon C, Poli G, Clementi M: Coronaviridae and SARS-associated coronavirus strain HSR-1. Emerging Infect Dis 2004;10:413-418.
6. Castilletti C, Bordi L, Lalle E, Rozera G, Poccia F, Agrati C, Abbate I, Capobianchi MR: Coordinate induction of IFN-α and -γ by SARS-CoV also in the absence of virus replication. Virology 2005;341:163-169.
7. Yilla M, Harcourt BH, Hickman CJ, McGrew M, Tamin A, Goldsmith CS, Bellini WJ, Anderson LJ: SARS-coronavirus replication in human peripheral monocytes/macrophages. Virus Res 2005;107:93-101.
8. Ng LF, Hibberd ML, Ooi EE, Tang KF, Neo SY, Tan J, Murthy KR, Vega VB, Chia JM, Liu ET, Ren EC: A human in vitro model system for investigating genome-wide host responses to SARS coronavirus infection. BMC Infect Dis 2004;4:34.
9. Loseke S, Grage-Griebenow E, Wagner A, Gehlhar K, Bufe A: Differential expression of IFN-α subtypes in human PBMCS: evaluation of novel real-time PCR assays. J Immunol Methods 2003;276:207-222.
10. Cheung CY, Poon LL, Ng IH, Luk W, Sia SF, Wu MH, Chan KH, Yuen KY, Gordon S, Guan Y, Peiris JS: Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis. J Virol 2005;79:7819-7826.
11. Yu SY, Hu YW, Liu XY, Xiong W, Zhou ZT, Yuan ZH: Gene expression profiles in peripheral blood mononuclear cells of SARS patients. World J Gastroenterol 2005;11:5037-5043.
12. Frieman M, Heise M, Baric R: SARS coronavirus and innate immunity. Virus Res 2008;133:101-112.
13. Cameron MJ, Bermejo-Martin JF, Danesh A, Muller MP, Kelvin DJ: Human immunopathogenesis of severe acute respiratory syndrome. Virus Res 2008;133:13-19.
14. Versteeg GA, Bredenbeek PJ, van den Worm SH, Spaan WJ: Group 2 coronaviruses prevent immediate early interferon induction by protection of viral RNA from host cell recognition. Virology 2007;361:18-26.
15. Tang BS, Chan KH, Cheng VC, Woo PC, Lau SK, Lam CC, Chan TL, Wu AK, Hung IF, Leung SY, Yuen KY: Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by severe acute respiratory syndrome coronavirus and human coronavirus 229E. J Virol 2005;79:6180-6193.
16. Law HK, Cheung CY, Ng HY, Sia SF, Chan YO, Luk W, Nicholls JM, Peiris JS, Lau YL: Chemokine up-regulation in SARS-coronavirus-infected, monocyte-derived human dendritic cells. Blood 2005;106:2366-2374.
17. Ziegler T, Matikainen S, Rönkkö E, Osterlund P, Sillanpää M, Sirénl J, Fagerlund R, Immonen M, Melén K, Julkunen I: Severe acute respiratory syndrome coronavirus fails to activate cytokine-mediated innate immune responses in cultured human monocyte-derived dendritic cells. J Virol 2005;79:13800-13805.
18. Spiegel M, Schneider K, Weber F, Weidmann M, Hufert FT: Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells. Gen Virol 2006;87:1953-1960.
19. Spiegel M, Weber F: Inhibition of cytokine gene expression and induction of chemokine genes in non-lymphatic cells infected with SARS coronavirus. J Virol 2006;293:17.
20. Cheung CY, Poon LL, Ng IH, Luk W, Sia SF, Wu MH, Chan KH, Yuen KY, Gordon S, Guan Y, Peiris JS: Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis. J Virol 2005;79:7819-7826.
21. Peiris M: Pathogenesis of avian flu H5N1 and SARS. Novartis Found Symp 2006;279:56-60.
22. Spiegel M, Pichlmair A, Martínez-Sobrido L, Cros J, García-Sastre A, Haller O, Weber F: Inhibition of β-interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3. J Virol 2005;79:2079-2086.
23. Kamitani W, Narayanan K, Huang C, Lokugamage K, Ikegami T, Ito N, Kubo H, Makino S: Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation. Proc Natl Acad Sci USA 2006;103:12885-12890.
24. Kopecky-Bromberg SA, Martinez-Sobrido L, Frieman M, Baric RA, Palese P: Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists. J Virol 2007;81:548-557.
25. De Lang A, Baas T, Teal T, Leijten LM, Rain B, Osterhaus AD, Haagmans BL, Katze MG: Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques. PLoS Pathog 2007;3:112.
26. Okabayashi T, Kariwa H, Yokota S, Iki S, Indoh T, Yokosawa N, Takashima I, Tsutsumi H, Fujii N: Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections. J Med Virol 2006;78:417-424.
27. Larrea E, Alberdi A, Castelruiz Y, Boya P, Civeira MP, Prieto J: Expression of interferon-α subtypes in peripheral mononuclear cells from patients with chronic hepatitis C: a role for interferon-α5. J Viral Hepat 2001;8:103-110.
28. Evinger M, Rubinstein M, Pestka S: Antiproliferative and antiviral activities of human leukocyte interferons. Arch Biochem Biophys 1981;210:319-329.
29. Fish EN, Banerjee K, Stebbing N: Human leukocyte interferon subtypes have different antiproliferative and antiviral activities on human cells. Biochem Biophys Res Commun 1983;112:537-546.
30. Foster GR, Rodrigues O, Ghouze F, Schulte-Frohlinde E, Testa D, Liao M J, Stark GR, Leadbeater L, Thomas HC: Different relative activities of human cell-derived interferon-alpha subtypes: IFN-α8 has very high antiviral potency. J Interferon Cytokine Res 1996;16:1027-1033.
31. Nyman TA, Tolo H, Parkkinen J, Kalkkinen N: Identification of nine interferon-α subtypes produced by Sendai virus-induced human peripheral blood leucocytes. Biochem J 1998;329:295-302.
32. Schanen C, Chieux V, Lobert PE, Harvey J, Hober D: Correlation between the antivirus-induced cytopathic effect activity of interferon-α subtypes and induction of MxA protein in vitro. Microbiol Immunol 2006;50:19-24.
33. Yamamoto S, Yano H, Sanou O, Ikegami H, Kurimoto M, Kojiro M: Different antiviral activities of IFN-α subtypes in human liver cell lines: synergism between IFN-α2 and IFN-α8. Hepatol Res 2002;24:99.
34. Koyama T, Sakamoto N, Tanabe Y, Nakagawa M, Itsui Y, Takeda Y, Kakinuma S, Sekine Y, Maekawa S, Yanai Y, Kurimoto M, Watanabe M: Divergent activities of interferon-α subtypes against intracellular hepatitis C virus replication. Hepatol Res 2006;34:41-49.