Structural biomechanics modulate intramuscular distribution of locally delivered drugs

Journal of Biomechanics

Volumn 41, Issue 13, 2008, Pages 2884-2891

  Wu, Peter I Kung ^a   Edelman, Elazer R ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Delivery; Mechanical; Muscle; Strain; Transport

Indexed keywords

BIOMECHANICS; COMPUTER NETWORKS; DRUG DELIVERY; DYNAMICS; GLUCOSE; LOADS (FORCES); MECHANICS; MODULATION; MUSCLE; PHARMACOKINETICS;

CYCLIC STRAINING; DELIVERY; MECHANICAL; STRAIN; TRANSPORT;

CONTROLLED DRUG DELIVERY;

FLUORESCEIN ISOTHIOCYANATE DEXTRAN;

ANIMAL TISSUE; ARTICLE; BIOMECHANICS; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG TRANSPORT; DRUG UPTAKE; DYNAMIC LOADING SYSTEM; DYNAMICS; INTRAMUSCULAR DRUG ADMINISTRATION; LOADING TEST; MALE; MECHANICAL LOADING; NONHUMAN; PRIORITY JOURNAL; RAT; SOLEUS MUSCLE;

ANIMALS; BIOMECHANICS; HEPARIN; MALE; MUSCLE, SKELETAL; RATS; RATS, SPRAGUE-DAWLEY; STRESS, MECHANICAL; TISSUE DISTRIBUTION; WEIGHT-BEARING;

EID: 51049093373     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2008.06.025     Document Type: Article

References (50)

1. Abraham K.A., and Terjung R.L. Phosphate uptake in rat skeletal muscle is reduced during isometric contractions. Journal of Applied Physiology 97 1 (2004) 57-62
2. Armstrong R.B., Duan C., Delp M.D., Hayes D.A., Glenn G.M., and Allen G.D. Elevations in rat soleus muscle [Ca2+] with passive stretch. Journal of Applied Physiology 74 6 (1993) 2990-2997
3. Aslesen R., Engebretsen E.M., Franch J., and Jensen J. Glucose uptake and metabolic stress in rat muscles stimulated electrically with different protocols. Journal of Applied Physiology 91 3 (2001) 1237-1244
4. Baker C.H., and Davis D.L. Isolated skeletal muscle blood flow and volume changes during contractile activity. Blood Vessels 11 1-2 (1974) 32-44
5. Baskin R.J., and Paolini P.J. Muscle volume changes. Journal of General Physiology 49 3 (1966) 387-404
6. Blomstrand E., Larsson L., and Edstrom L. Contractile properties, fatiguability and glycolytic metabolism in fast- and slow-twitch rat skeletal muscles of various temperatures. Acta Physiologica Scandinavica 125 2 (1985) 235-243
7. Cappelli V., Poggesi C., Ricciardi L., and Reggiani C. Tritiated water (hto) and inulin spaces in isolated skeletal and cardiac muscles: influence of contractile activity. Experientia 37 8 (1981) 849-850
8. Constable S.H., Favier R.J., Cartee G.D., Young D.A., and Holloszy J.O. Muscle glucose transport: interactions of in vitro contractions, insulin, and exercise. Journal of Applied Physiology 64 6 (1988) 2329-2332
9. Creese R., D'Silva J.L., and Hashish S.E. Inulin space and fibre size of stimulated rat muscle. Journal of Physiology 127 3 (1955) 525-532
10. Elmquist S., Libelius R., Lawoko G., and Tagerud S. Dextrans as markers for endocytosis in innervated and denervated skeletal muscle. Muscle and Nerve 15 8 (1992) 876-884
11. Epstein S.E., Fuchs S., Zhou Y.F., Baffour R., and Kornowski R. Therapeutic interventions for enhancing collateral development by administration of growth factors: basic principles, early results and potential hazards. Cardiovascular Research 49 3 (2001) 532-542
12. Ettema G.J. Mechanical behaviour of rat skeletal muscle during fatiguing stretch-shortening cycles. Experimental Physiology 82 1 (1997) 107-119
13. Ettema G.J., Goh J.T., and Forwood M.R. A new method to measure elastic properties of plastic-viscoelastic connective tissue. Medical Engineering and Physics 20 4 (1998) 308-314
14. Fry D.L., Mahley R.W., and Oh S.Y. Effect of arterial stretch on transmural albumin and evan's blue dye transport. American Journal of Physiology: Heart and Circulatory Physiology 240 4 (1981) H645-H649
15. Gauthier M.G., and Slater G.W. Exactly solvable Ogston model of gel electrophoresis. IX. Generalizing the lattice model to treat high field intensities. Journal of Chemical Physics 117 14 (2002) 6745-6756
16. Gissel H., and Clausen T. Excitation-induced Ca2+ uptake in rat skeletal muscle. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 276 2 Pt 2 (1999) R331-R339
17. Gissel H., and Clausen T. Excitation-induced Ca(2+) influx in rat soleus and edl muscle: mechanisms and effects on cellular integrity. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 279 3 (2000) R917-R924
18. Han S., Gemmell S.J., Helmer K.G., Grigg P., Wellen J.W., Hoffman A.H., and Sotak C.H. Changes in ADC caused by tensile loading of rabbit Achilles tendon: evidence for water transport. Journal of Magnetic Resonance 144 2 (2000) 217-227
19. Hawkins D., and Bey M. Muscle and tendon force-length properties and their interactions in vivo. Journal of Biomechanics 30 1 (1997) 63-70
20. Helmer K.G., Nair G., Cannella M., and Grigg P. Water movement in tendon in response to a repeated static tensile load using one-dimensional magnetic resonance imaging. Journal of Biomechanical Engineering 128 5 (2006) 733-741
21. Holloszy J.O., and Narahara H.T. Studies of tissue permeability X. Changes in permeability to 3-methylglucose associated with contraction of isolated frog muscle. Journal of Biological Chemistry 240 9 (1965) 3493-3500
22. Huang C.Y., and Gu W.Y. Effects of tension-compression nonlinearity on solute transport in charged hydrated fibrous tissues under dynamic unconfined compression. Journal of Biomechanical Engineering 129 3 (2007) 423-429
23. Ihlemann J., Ploug T., Hellsten Y., and Galbo H. Effect of tension on contraction-induced glucose transport in rat skeletal muscle. American Journal of Physiology: Endocrinology and Metabolism 277 2 Pt 1 (1999) E208-E214
24. Ihlemann J., Ploug T., Hellsten Y., and Galbo H. Effect of stimulation frequency on contraction-induced glucose transport in rat skeletal muscle. American Journal of Physiology: Endocrinology and Metabolism 279 4 (2000) E862-E867
25. Ihlemann J., Ploug T., and Galbo H. Effect of force development on contraction induced glucose transport in fast twitch rat muscle. Acta Physiologica Scandinavica 171 4 (2001) 439-444
26. Loeffler III L., and Sagawa K. A one-dimensional viscoelastic model of cat heart muscle studied by small length perturbations during isometric contraction. Circulation Research 36 4 (1975) 498-512
27. Lovich M.A., and Edelman E.R. Tissue average binding and equilibrium distribution: an example with heparin in arterial tissues. Biophysical Journal 70 3 (1996) 1553-1559
28. McCarthy M.J., Soong D.S., and Edelman E.R. Control of drug release from polymer matrices impregnated with magnetic beads-a proposed mechanism and model for enhanced release. Journal of Controlled Release 1 (1984) 143-147
29. McDermott J.C., and Bonen A. Lactate transport in rat sarcolemmal vesicles and intact skeletal muscle, and after muscle contraction. Acta Physiologica Scandinavica 151 1 (1994) 17-28
30. Mehvar R. Dextrans for targeted and sustained delivery of therapeutic and imaging agents. Journal of Controlled Release 69 1 (2000) 1-25
31. Meyer G., Merval R., and Tedgui A. Effects of pressure-induced stretch and convection on low-density lipoprotein and albumin uptake in the rabbit aortic wall. Circulation Research 79 3 (1996) 532-540
32. Osman F.H., Munson J.L., and Paton D.M. Estimation of extracellular space in rabbit detrusor muscle. Comparative Biochemistry and Physiology. A, Comparative Physiology 40 1 (1971) 45-54
33. Papadopoulos S., Jurgens K.D., and Gros G. Protein diffusion in living skeletal muscle fibers: dependence on protein size, fiber type, and contraction. Biophysical Journal 79 4 (2000) 2084-2094
34. Petrofsky J.S., and Lind A.R. The influence of temperature on the isometric characteristics of fast and slow muscle in the cat. Pflügers Archiv: European Journal of Physiology 389 2 (1981) 149-154
35. Purslow P.P. Strain-induced reorientation of an intramuscular connective tissue network: implications for passive muscle elasticity. Journal of Biomechanics 22 1 (1989) 21-31
36. Purslow P.P., and Trotter J.A. The morphology and mechanical properties of endomysium in series-fibred muscles: variations with muscle length. Journal of Muscle Research and Cell Motility 15 3 (1994) 299-308
37. Quinn T.M., Morel V., and Meister J.J. Static compression of articular cartilage can reduce solute diffusivity and partitioning: implications for the chondrocyte biological response. Journal of Biomechanics 34 11 (2001) 1463-1469
38. Rankin L.L., Enoka R.M., Volz K.A., and Stuart D.G. Coexistence of twitch potentiation and tetanic force decline in rat hindlimb muscle. Journal of Applied Physiology 65 6 (1988) 2687-2695
39. Rutili G., and Arfors K.E. Fluorescein-labelled dextran measurement in interstitial fluid in studies of macromolecular permeability. Microvascular Research 12 2 (1976) 221-230
40. Ryall J.G., Gregorevic P., Plant D.R., Sillence M.N., and Lynch G.S. Beta 2-agonist fenoterol has greater effects on contractile function of rat skeletal muscles than clenbuterol. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 283 6 (2002) R1386-R1394
41. Schroder U., Arfors K.E., and Tangen O. Stability of fluorescein labeled dextrans in vivo and in vitro. Microvascular Research 11 1 (1976) 57-66
42. Segal S.S., and Faulkner J.A. Temperature-dependent physiological stability of rat skeletal muscle in vitro. American Journal of Physiology: Cell Physiology 248 3 Pt 1 (1985) C265-C270
43. Sreter F.A. Cell water, sodium, and potassium in stimulated red and white mammalian muscles. American Journal of Physiology 205 (1963) 1295-1298
44. Sreter F.A. Distribution of water, sodium, and potassium in resting and stimulated mammalian muscle. Canadian Journal of Biochemistry and Physiology 41 (1963) 1035-1045
45. Templeton G.H., Donald III T.C., Mitchell J.H., and Hefner L.L. Dynamic stiffness of papillary muscle during contraction and relaxation. American Journal of Physiology 224 3 (1973) 692-698
46. Trombitas K., Baatsen P., Schreuder J., and Pollack G.H. Contraction-induced movements of water in single fibres of frog skeletal muscle. Journal of Muscle Research and Cell Motility 14 6 (1993) 573-584
47. van Donkelaar C.C., Willems P.J., Muijtjens A.M., and Drost M.R. Skeletal muscle transverse strain during isometric contraction at different lengths. Journal of Biomechanics 32 8 (1999) 755-762
48. Ward D.S., Hamilton M.T., and Watson P.D. Measurement of tissue volume during non-steady state high-intensity muscle contraction. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 271 6 Pt 2 (1996) R1682-R1690
49. Wisnes A., and Kirkebo A. Regional distribution of blood flow in calf muscles of rat during passive stretch and sustained contraction. Acta Physiologica Scandinavica 96 2 (1976) 256-266
50. Zuurbier C.J., and Huijing P.A. Changes in geometry of actively shortening unipennate rat gastrocnemius muscle. Journal of Morphology 218 2 (1993) 167-180