Effect of intra-articular dexmedetomidine on postoperative analgesia after arthroscopic knee surgery

British Journal of Anaesthesia

Volumn 101, Issue 3, 2008, Pages 395-399

  Al Metwalli, R R ^a   Mowafi, H A ^a   Ismail, S A ^a   Siddiqui, A K ^a   Al Ghamdi, A M ^a   Shafi, M A ^a   El Saleh, A R ^a  

^a KING FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

Analgesia, postoperative; Analgesic techniques, intra articular; Analgesics non opioid, diclofenac; Surgery, orthopaedic; Sympathetic nervous system, dexmedetomidine

Indexed keywords

DEXMEDETOMIDINE; DICLOFENAC; PLACEBO; TRAMADOL; ANALGESIC AGENT;

ADULT; AGED; ARTHROSCOPIC SURGERY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HEMODYNAMICS; HUMAN; KNEE ARTHROSCOPY; KNEE SURGERY; MALE; NAUSEA; PAIN ASSESSMENT; POSTOPERATIVE ANALGESIA; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PAIN; PRIORITY JOURNAL; SEDATION; VISUAL ANALOG SCALE; VOMITING; ARTHROSCOPY; BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; HEART RATE; INTRAARTICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; KNEE; METHODOLOGY; MIDDLE AGED; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; ANALGESICS, NON-NARCOTIC; ARTHROSCOPY; BLOOD PRESSURE; DEXMEDETOMIDINE; DOUBLE-BLIND METHOD; FEMALE; HEART RATE; HUMANS; INJECTIONS, INTRA-ARTICULAR; INJECTIONS, INTRAVENOUS; KNEE JOINT; MALE; MIDDLE AGED; PAIN MEASUREMENT; PAIN, POSTOPERATIVE;

EID: 50949134176     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aen184     Document Type: Article

References (20)

1. Bondok RS, Abd El-Hady AM. Intra-articular magnesium is effective for postoperative analgesia in arthroscopic knee surgery. Br J Anaesth 2006; 97: 389-392
2. Gentili M, Houssel P, Osman M, Henel D, Juhel A, Bonnet F. Intra-articular morphine and clonidine produce comparable analgesia but the combination is not more effective. Br J Anaesth 1997; 79: 660-661
3. Buerkle H, Huge V, Wolfgart M, et al. Intra-articular clonidine analgesia after knee arthroscopy. Eur J Anaesthesiol 2000; 17: 295-299
4. Reuben SS, Connelly NR. Postoperative analgesia for outpatient arthroscopic knee surgery with intraarticular clonidine. Anesth Analg 1999; 88: 729-733
5. Tan PH, Buerkle H, Cheng JT, Shih HC, Chou WY, Yang LC. Double-blind parallel comparison of multiple doses of apraclonidine, clonidine, and placebo administered intra-articularly to patients undergoing arthroscopic knee surgery. Clin J Pain 2004; 20: 256-260
6. Gerlach AT, Dasta JF. Dexmedetomidine: an updated review. Ann Pharmacother 2007; 41: 245-252
7. Hayashi Y, Maze M. Alpha-2 adrenoceptor agonists and anaesthesia. Br J Anaesth 1993; 71: 108-118
8. Karaaslan D, Peker TT, Alaca A, et al. Comparison of buccal and intramuscular dexmedetomidine premedication for arthroscopic knee surgery. J Clin Anesth 2006; 18: 589-593
9. Gómez-Vázquez ME, Hernández-Salazar E, Hernández-Jiménez A, Pérez-Sánchez A, Zepeda-López VA, Salazar-Páramo M. Clinical analgesic efficacy and side effects of dexmedetomidine in the early postoperative period after arthroscopic knee surgery. J Clin Anesth 2007; 19: 576-582
10. Chernik DA, Gillings D, Laine H, et al. Validity and reliability of the Observer's Assessment of Alertness/Sedation Scale: study with intravenous midazolam. J Clin Psychopharmacol 1990; 10: 244-251
11. Ebert TJ, Hall JE, Barney JA, Ulrich TD, Colinco MD. The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology 2000; 93: 382-394
12. Gentili M, Juhel A, Bonnet F. Peripheral analgesic effect of intra-articular clonidine. Pain 1996; 64: 593-596
13. Butterworth JFV, Strichartz GR. The alpha 2-adrenergic agonists clonidine and gunafacine produce tonic and phasic block of conduction in rat sciatic nerve fibers. Anesth Analg 1993; 76: 295-301
14. Nakamura M, Ferreira SH. Peripheral analgesic action of clonidine: mediation by release of endogenous enkephalin-like substances. Eur J Pharmacol 1988; 146: 223-228
15. Post C, Archer T, Minor BG. Evidence for cross tolerance to the analgesic effects between morphine and selective alpha 2- adrenergic agonists. J Neural Transm 1988; 72: 1-9
16. Buerkle H, Schäpsmeier M, Bantel C, Marcus MA, Wüsten R, Van Aken H. Thermal and mechanical antinociceptive action of spinal vs peripherally administered clonidine in the rat inflamed knee joint model. Br J Anaesth 1999; 83: 436-441
17. Khasar SG, Green PG, Chou B, Levine JD. Peripheral nociceptive effects of alpha 2-adrenergic receptor agonists in the rat. Neuroscience 1995; 66: 427-432
18. Joshi W, Reuben SS, Kilaru PR, Sklar J, Maciolek H. Postoperative analgesia for outpatient arthroscopic knee surgery with intraarticular clonidine and/or morphine. Anesth Analg 2000; 90: 1102-1106
19. Ansah OB, Pertovaara A. Peripheral suppression of arthritic pain by intraarticular fadolmidine, an alpha 2-adrenoceptor agonist, in the rat. Anesth Analg 2007; 105: 245-250
20. Dye SF, Vaupel GL, Dye CC. Conscious neurosensory mapping of the internal structures of the human knee without intraarticular anesthesia. Am J Sports Med 1998; 26: 773-777