Magnitude, Reproducibility, and Association With Baseline Cardiac Function of Cardiac Biomarker Release in Long-Distance Runners Aged ≥55 Years

American Journal of Cardiology

Volumn 102, Issue 2, 2008, Pages 218-222

  Sahlén, Anders ^a   Winter, Reidar ^a   Lind, Britta ^a   Jacobsen, Per Herman ^a   Ståhlberg, Marcus ^a   Marklund, Tony ^b   Fux, Thomas ^a   Svensson, Jan ^c   Braunschweig, Frieder ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Roche AB   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOLOGICAL MARKER; TROPONIN T;

ADULT; ARTICLE; CLINICAL ARTICLE; ECHOCARDIOGRAPHY; FEMALE; HEART FUNCTION; HEART LEFT VENTRICLE MASS; HUMAN; MALE; PRIORITY JOURNAL; REPRODUCIBILITY; RUNNING;

AGE FACTORS; BIOLOGICAL MARKERS; EXERCISE TOLERANCE; FEMALE; HEART; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; RUNNING; TIME FACTORS;

EID: 50949129269     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2008.03.042     Document Type: Article

References (19)

1. Lang R.M., Bierig M., Devereux R.B., Flachskampf F.A., Foster E., Pellikka P.A., Picard M.H., Roman M.J., Seward J., Shanewise J.S., et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 18 (2005) 1440-1463
2. Fraser A.G., Payne N., Madler C.F., Janerot-Sjoberg B., Lind B., Grocott-Mason R.M., Ionescu A.A., Florescu N., Wilkenshoff U., Lancellotti P., et al. Feasibility and reproducibility of off-line tissue Doppler measurement of regional myocardial function during dobutamine stress echocardiography. Eur J Echocardiogr 4 (2003) 43-53
3. Herrmann M., Scharhag J., Miclea M., Urhausen A., Herrmann W., and Kindermann W. Post-race kinetics of cardiac troponin T and I and N-terminal pro-brain natriuretic peptide in marathon runners. Clin Chem 49 (2003) 831-834
4. Leers M.P., Schepers R., and Baumgarten R. Effects of a long-distance run on cardiac markers in healthy athletes. Clin Chem Lab Med 44 (2006) 999-1003
5. Scharhag J., Urhausen A., Schneider G., Herrmann M., Schumacher K., Haschke M., Krieg A., Meyer T., Herrmann W., and Kindermann W. Reproducibility and clinical significance of exercise-induced increases in cardiac troponins and N-terminal pro brain natriuretic peptide in endurance athletes. Eur J Cardiovasc Prev Rehabil 13 (2006) 388-397
6. Middleton N., Shave R., George K., Whyte G., Hart E., Oxborough D., Forster J., and Gaze D. Altered left ventricular diastolic filling following a marathon is a reproducible phenomenon. Int J Cardiol 122 (2007) 87-89
7. Neumayr G., Pfister R., Mitterbauer G., Eibl G., and Hoertnagl H. Effect of competitive marathon cycling on plasma N-terminal pro-brain natriuretic peptide and cardiac troponin T in healthy recreational cyclists. Am J Cardiol 96 (2005) 732-735
8. Scharhag J., Herrmann M., Urhausen A., Haschke M., Herrmann W., and Kindermann W. Independent elevations of N-terminal pro-brain natriuretic peptide and cardiac troponins in endurance athletes after prolonged strenuous exercise. Am Heart J 150 (2005) 1128-1134
9. Neumayr G., Gaenzer H., Pfister R., Sturm W., Schwarzacher S.P., Eibl G., Mitterbauer G., and Hoertnagl H. Plasma levels of cardiac troponin I after prolonged strenuous endurance exercise. Am J Cardiol 87 (2001) 369-371
10. Fortescue E.B., Shin A.Y., Greenes D.S., Mannix R.C., Agarwal S., Feldman B.J., Shah M.I., Rifai N., Landzberg M.J., Newburger J.W., and Almond C.S. Cardiac troponin increases among runners in the Boston Marathon. Ann Emerg Med 49 (2007) 137-143
11. Hart E., Shave R., Middleton N., George K., Whyte G., and Oxborough D. Effect of preload augmentation on pulsed wave and tissue Doppler echocardiographic indices of diastolic function after a marathon. J Am Soc Echocardiogr 20 (2007) 1393-1399
12. Ashley E.A., Kardos A., Jack E.S., Habenbacher W., Wheeler M., Kim Y.M., Froning J., Myers J., Whyte G., Froelicher V., and Douglas P. Angiotensin-converting enzyme genotype predicts cardiac and autonomic responses to prolonged exercise. J Am Coll Cardiol 48 (2006) 523-531
13. Neilan T.G., Januzzi J.L., Lee-Lewandrowski E., Ton-Nu T.T., Yoerger D.M., Jassal D.S., Lewandrowski K.B., Siegel A.J., Marshall J.E., Douglas P.S., et al. Myocardial injury and ventricular dysfunction related to training levels among nonelite participants in the Boston marathon. Circulation 114 (2006) 2325-2333
14. Nikitin N.P., Witte K.K., Thackray S.D., de Silva R., Clark A.L., and Cleland J.G. Longitudinal ventricular function: normal values of atrioventricular annular and myocardial velocities measured with quantitative two-dimensional color Doppler tissue imaging. J Am Soc Echocardiogr 16 (2003) 906-921
15. Gerstenblith G., Frederiksen J., Yin F.C., Fortuin N.J., Lakatta E.G., and Weisfeldt M.L. Echocardiographic assessment of a normal adult aging population. Circulation 56 (1977) 273-278
16. Palka P., Lange A., and Nihoyannopoulos P. The effect of long-term training on age-related left ventricular changes by Doppler myocardial velocity gradient. Am J Cardiol 84 (1999) 1061-1067
17. Wang T.J., Larson M.G., Levy D., Benjamin E.J., Leip E.P., Omland T., Wolf P.A., and Vasan R.S. Plasma natriuretic peptide levels and the risk of cardiovascular events and death. N Engl J Med 350 (2004) 655-663
18. Olsen M.H., Hansen T.W., Christensen M.K., Gustafsson F., Rasmussen S., Wachtell K., Ibsen H., Torp-Pedersen C., and Hildebrandt P.R. N-terminal pro-brain natriuretic peptide, but not high sensitivity C-reactive protein, improves cardiovascular risk prediction in the general population. Eur Heart J 28 (2007) 1374-1381
19. Montgomery H.E., Clarkson P., Dollery C.M., Prasad K., Losi M.A., Hemingway H., Statters D., Jubb M., Girvain M., Varnava A., et al. Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation 96 (1997) 741-747