The type II collagen fragments Helix-II and CTX-II reveal different enzymatic pathways of human cartilage collagen degradation

Osteoarthritis and Cartilage

Volumn 16, Issue 10, 2008, Pages 1183-1191

  Charni Ben Tabassi, N ^a   Desmarais, S ^b   Bay Jensen, A C ^c   Delaisse J M ^c   Percival, M D ^b   Garnero, P ^a,d  

^a Synarc   (France)

^b MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d INSERM   (France)

Author keywords

Cartilage; Cathepsins; CTX II; Helix II; Matrix metalloproteinases; Osteoarthritis

Indexed keywords

CARBOXY TERMINAL TELOPEPTIDE; CATHEPSIN B; CATHEPSIN D; CATHEPSIN K; CATHEPSIN L; CATHEPSIN S; COLLAGEN TYPE 2; COLLAGENASE 3; GELATINASE B; HYDROXYPROLINE; ILOMASTAT; INTERSTITIAL COLLAGENASE; MATRILYSIN; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; RECOMBINANT ENZYME; STROMELYSIN;

ACCURACY; ADULT; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE DEGENERATION; CASE REPORT; COLLAGEN DEGRADATION; DISEASE COURSE; DISEASE MARKER; ENZYME ACTIVITY; EX VIVO STUDY; EXPLANT; FEMALE; FROZEN SECTION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; KNEE OSTEOARTHRITIS; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; TOTAL KNEE REPLACEMENT;

BIOLOGICAL MARKERS; CARTILAGE, ARTICULAR; CATHEPSINS; COLLAGEN TYPE II; HUMANS; MATRIX METALLOPROTEINASES; OSTEOARTHRITIS, KNEE; PREDICTIVE VALUE OF TESTS;

EID: 50949128814     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2008.02.008     Document Type: Article

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