Toxic lopinavir concentrations in an HIV-1 infected patient taking herbal medications

AIDS

Volumn 22, Issue 10, 2008, Pages 1243-1244

  Beukel Van Den Bout Van Den, Carolien J P ^a,c   Bosch, Marjolein E W ^a,c   Burger, David M ^b,c   Koopmans, Peter P ^a,c   Van Der Ven, André J A M ^a,c  

^a Department of General Internal Medicine ^*  (Netherlands)

^b Clinical Pharmacy   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COLAYUR; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; HERBACEOUS AGENT; LAMIVUDINE; LOPINAVIR; LOPINAVIR PLUS RITONAVIR; PRIMROSE OIL; RHEUM FRANGULA EXTRACT; STAVUDINE; TENOFOVIR; UNCLASSIFIED DRUG; DRUG; PROTEINASE INHIBITOR; PYRIMIDINONE DERIVATIVE;

ADULT; CASE REPORT; CLINICAL FEATURE; DIARRHEA; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG METABOLISM; DRUG SUBSTITUTION; DRUG WITHDRAWAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LETTER; LIPODYSTROPHY; MALE; PRIORITY JOURNAL; PROVOCATION TEST; RHEUM FRANGULA; RHUBARB; CHEMICALLY INDUCED DISORDER; HERB DRUG INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS 1; MIDDLE AGED;

DIARRHEA; HERB-DRUG INTERACTIONS; HIV INFECTIONS; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; MALE; MIDDLE AGED; PHARMACEUTICAL PREPARATIONS; PYRIMIDINONES;

EID: 50949123788     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32830261f4     Document Type: Letter

References (10)

1. Ernst E. Complementary AIDS therapies: the good, the bad and the ugly. Int J STD AIDS 1997; 8:281-285.
2. Sparber A, Wootton JC, Bauer L, Curt G, Eisenberg D, Levin T, et al. Use of complementary medicine by adult patients participating in HIV/AIDS clinical trials. J Ahem Complement Med 2000; 6:415-422.
3. Gore-Felton C, Vosvick M, Power R, Koopman C, Ashton E, Bachmann MH, et al. Alternative therapies: a common practice among men and women living with HIV. J Assoc Nurses AIDS Care 2003; 14:17-27.
4. de Maat MM, Ekhart GC, Huitema AD, Koks CH, Mulder JW, Beijnen JH. Drug interactions between antiretroviral drugs and comedicated agents. Clin Pharmacokinet 2003; 42:223-282.
5. Hurst M, Faulds D. Lopinavir. Drugs 2000; 60:1371-1379.
6. Zou L, Harkey MR, Henderson GL. Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity. Life Sci 2002; 71:1579-1589.
7. BlumenthalM, FerrierGKL, Cavalier, C. FDM Market Sales Data for Herbal Supplements, 52 weeks ending January 1, 2006. Chicago, IL: Information Resources Inc.; 2006.
8. van den Bout-van den Beukel CJ, Koopmans PP, van der Ven A, De Smet PA, Burger DM. Possible drug-metabolism interactions of medicinal herbs with antiretroviral agents. Drug Metab Rev 2006; 38:477-514.
9. Risa KJ, Nepon L, Justis JC, Panwalker A, Berman SM, Cinti S, et al. Alternative therapy use in HIV-infected patients receiving highly active antiretroviral therapy. Int J STD AIDS 2002; 13:706-713.
10. Lee LS, Andrade AS, Flexner C. Interactions between natural health products and antiretroviral drugs: pharmacokinetic and pharmacodynamic effects. Clin Infect Dis 2006; 43:1052-1059.