Hemorrhagic activity of the vascular apoptosis-inducing proteins VAP1 and VAP2 from Crotalus atrox

Toxicon

Volumn 52, Issue 4, 2008, Pages 589-593

  Kikushima, Eiichi ^a   Nakamura, Shiho ^a   Oshima, Yasunori ^a   Shibuya, Tomoko ^a   Miao, Jun Ying ^b   Hayashi, Hiroshi ^a   Nikai, Toshiaki ^c   Araki, Satohiko ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b SHANDONG UNIVERSITY   (China)

^c MEIJO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Endothelial cell; Hemorrhage; Snake venom; Vascular

Indexed keywords

SNAKE VENOM; TOXIN; UNCLASSIFIED DRUG; VASCULAR APOPTOSIS INDUCING PROTEIN 1; VASCULAR APOPTOSIS INDUCING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEEDING; CONTROLLED STUDY; INTESTINAL BLEEDING; KIDNEY HEMORRHAGE; LUNG HEMORRHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN BLEEDING; SNAKE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CROTALID VENOMS; CROTALUS; HEMORRHAGE; MALE; METALLOENDOPEPTIDASES; MICE; SKIN; TOXICITY TESTS;

CROTALUS ATROX;

EID: 50949110231     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.06.027     Document Type: Article

References (35)

1. Araki S., Shimada Y., Kaji K., and Hayashi H. Apoptosis of vascular endothelial cells by fibroblast growth factor deprivation. Biochem. Biophys. Res. Commun. 168 (1990) 1194-1200
2. Araki S., Ishida T., Yamamoto T., Kaji K., and Hayashi H. Induction of apoptosis by hemorrhagic snake venom in vascular endothelial cells. Biochem. Biophys. Res. Commun. 190 (1993) 148-153
3. Araki S., Masuda S., Maeda H., Ying M.J., and Hayashi H. Involvement of specific integrins in apoptosis induced by vascular apoptosis-inducing protein 1. Toxicon 40 (2002) 535-542
4. Bjarnason J.B., and Fox J.W. Hemorrhagic toxins from snake venoms. J. Toxicol. Toxins Rev. 7 (1988/89) 121-209
5. Bjarnason J.B., and Fox J.W. Hemorrhagic metalloproteinases from snake venoms. Pharmacol. Ther. 62 (1994) 325-372
6. Bjarnason J.B., and Tu A.T. Hemorrhagic toxins from Western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin. Biochemistry 17 (1978) 3395-3404
7. Chakrabarty D., Bhattacharyya D., Sarkar H.S., and Lahiri S.C. Purification and partial characterization of a haemorrhagin (VRH-1) from Vipera russelli russelli venom. Toxicon 31 (1993) 1601-1614
8. Escalante T., Shannon J., Moura-da-Silva A.M., Gutiérrez J.M., and Fox J.W. Novel insights into capillary vessel basement membrane damage by snake venom hemorrhagic metalloproteinases: a biochemical and immunohistochemical study. Arch Biochem Biophys. 455 (2006) 144-153
9. Gutiérrez J.M., Rucavado A., Escalante T., and Di'az C. Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage. Toxicon 45 (2005) 997-1011
10. Igarashi T., Araki S., Mori H., and Takeda S. Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins. FEBS Lett. 581 13 (2007) 2416-2422
11. Johnson E.K., and Ownby C.L. Isolation of a hemorrhagic toxin from the venom of Agkistrodon contortrix laticinctus (broad-banded copperhead) and pathogenesis of the hemorrhage induced by the toxin in mice. Int. J. Biochem. 25 (1993) 267-278
12. Kamiguti A.S., Hay C.R., and Zuzel M. Inhibition of collagen-induced platelet aggregation as the result of cleavage of alpha 2 beta 1-integrin by the snake venom metalloproteinase jararhagin. Biochem. J. 320 Pt 2 (1996) 635-641
13. Komori Y., Nikai T., and Sugihara H. Comparative study of Agkistrodon acutus venoms from China and Taiwan. Comp. Biochem. Physiol. C 79 (1984) 51-57
14. Li D., Yang B., and Mehta J.L. Ox-LDL induces apoptosis in human coronary artery endothelial cells: role of PKC, PTK, bcl-2, and Fas. Am. J. Physiol. 275 (1998) H568-H576
15. Maruyama J., Hayashi H., Miao J.Y., Sawada H., and Araki S. Severe cell fragmentation in the endothelial cell apoptosis induced by snake apoptosis toxin VAP1 is an apoptotic characteristic controlled by caspases. Toxicon 46 (2005) 1-6
16. Masuda S., Araki S., Kaji K., and Hayashi H. Purification of a vascular apoptosis-inducing factor from hemorrhagic snake venom. Biochem. Biophys. Res. Commun. 235 (1997) 59-63
17. Masuda S., Hayashi H., and Araki S. Two vascular apoptosis-inducing proteins from snake venom are members of the metalloprotease/disintegrin family. Eur. J. Biochem. 253 (1998) 36-41
18. Masuda S., Hayashi H., Atoda H., Morita T., and Araki S. Purification, cDNA cloning and characterization of the vascular apoptosis-inducing protein, HV1, from Trimeresurus flavoviridis. Eur. J. Biochem. 268 (2001) 3339-3345
19. Masuda S., Maeda H., Miao J.Y., Hayashi H., and Araki S. cDNA cloning and some additional peptide characterization of a single-chain vascular apoptosis-inducing protein, VAP2. Endothelium 14 (2007) 89-96
20. Masuda S., Ohta T., Kaji K., Fox J.W., Hayashi H., and Araki S. cDNA cloning and characterization of vascular apoptosis-inducing protein 1. Biochem. Biophys. Res. Commun. 278 (2000) 197-204
21. Meredith Jr. J.E., Fazeli B., and Schwartz M.A. The extracellular matrix as a cell survival factor. Mol. Biol. Cell 4 (1993) 953-961
22. Moura-da-Silva A.M., Ramos O.H., Baldo C., Niland S., Hansen U., Ventura J.S., Furlan S., Butera D., Della-Casa M.S., Tanjoni I., Clissa P.B., Fernandes I., Chudzinski-Tavassi A.M., and Eble J.A. Collagen binding is a key factor for the hemorrhagic activity of snake venom metalloproteinases. Biochimie 4 (2007) 1-9 Epub Dec
23. Omori-Satoh T., and Sadahiro S. Resolution of the major hemorrhagic component of Trimeresurus flavoviridis venom into two parts. Biochim. Biophys. Acta 580 (1979) 392
24. Oshima G., Ohmari-Satoh T., Iwanaga S., and Suzuki T. Studies on snake venom hemorrhagic factor I (HR-I) in the venom of Agkistrodon halys blomhoffi. J. Biochem. 72 (1972) 1483
25. Ownby C.L. Locally acting agents: myotoxins, hemorrhagic toxins and dermonecrotic factors. In: Shier W.T., and Mebs D. (Eds). Handbook of Toxinology (1990), Marcel Dekker, New York 602-654
26. Schattner M., Fritzen M., Ventura Jde S., de Albuquerque Modesto J.C., Pozner R.G., Moura-da-Silva A.M., and Chudzinski-Tavassi A.M. The snake venom metalloproteases berythractivase and jararhagin activate endothelial cells. Biol. Chem. 386 (2005) 369-374
27. Takahashi T., and Osaka A. Purification and some properties of two hemorrhagic principles (HR2a and HR2b) in the venom of Trimeresurus flavoviridis; complete separation of the principles from proteolytic activity. Biochim. Biophys. Acta 207 (1970) 65-75
28. Takeda S., Igarashi T., Mori H., and Araki S. Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold. EMBO J. 25 (2006) 2388-2396
29. Takeya H., Oda K., Miyata T., Omori-Satoh T., and Iwanaga S. The complete amino acid sequence of the high molecular mass hemorrhagic protein HR1B isolated from the venom of Trimeresurus flavoviridis. J. Biol. Chem. 265 (1990) 16068-16073
30. Than T., Thwin M.M., Pe U., and San M.K. Distribution of 125 I-labelled Russell's viper (Vipera russell) venom in mice. Snake 17 (1985) 124-130
31. Theakston R.D.G., and Reid H.A. Development of simple standard assay procedures for the characterization of snake venoms. Bull. WHO 61 (1983) 949-956
32. Trummal K., Tonismagi K., Siigur E., Aaspollu A., Lopp A., Sillat T., Saat R., Kasak L., Tammiste I., Kogerman P., Kalkkinen N., and Siigur J. A novel metalloprotease from Vipera lebetina venom induces human endothelial cell apoptosis. Toxicon 46 (2005) 46-61
33. Wang W.J., Shih C.H., and Huang T.F. Primary structure and antiplatelet mechanism of a snake venom metalloproteinase, acurhagin, from Agkistrodon acutus venom. Biochimie 87 (2005) 1065-1077
34. You W.K., Seo H.J., Chung K.H., and Kim D.S. A novel metalloprotease from Gloydius halys venom induces endothelial cell apoptosis through its protease and disintegrin-like domains. J. Biochem. (Tokyo) 134 (2003) 739-749
35. Zhou Q., Smith J.B., and Grossman M.H. Molecular cloning and expression of catrocollastatin, a snake venom protein from Crotarus atrox (western diamondback rattlesnake) which inhibits platelet adhesion to collagen. Biochem. J. 307 (1995) 411-417