Consanguineous marriages and endemic malaria: Can inbreeding increase population fitness?

Malaria Journal

Volumn 7, Issue , 2008, Pages

  Denic, Srdjan ^a   Nagelkerke, Nicolas ^a,b   Agarwal, Mukesh M ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ALPHA THALASSEMIA; ARTICLE; CONSANGUINEOUS MARRIAGE; ENDEMIC DISEASE; FATALITY; FIELD STUDY; FITNESS; GENOTYPE; HOMOZYGOSITY; HUMAN; INBREEDING; MALARIA; MORTALITY; OUTBREEDING; POPULATION GROWTH; STOCHASTIC MODEL; SURVIVAL TIME; CONSANGUINITY; GENE FREQUENCY; GENETICS; HOMOZYGOTE; POPULATION GENETICS; THEORETICAL MODEL;

ALPHA-THALASSEMIA; CONSANGUINITY; ENDEMIC DISEASES; GENE FREQUENCY; GENETICS, POPULATION; HOMOZYGOTE; HUMANS; MALARIA; MODELS, THEORETICAL;

EID: 50849141375     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-7-150     Document Type: Article

References (26)

1. Consanguinity and its relevance to clinical genetics. A Bittles, Clin Genet 2001 60 89 98 10.1034/j.1399-0004.2001.600201.x 11553039
2. Genetic benefits of consanguinity through selection of genotypes protective against malaria. S Denic MG Nicholls, Hum Biol 2007 79 145 158 10.1353/hub.2007.0030 18027811
3. +-Thalassaemia protects children against disease caused by other infections as well as malaria. SJ Allen A O'Donnell ND Alexander MP Alpers TE Peto JB Clegg DJ Weatherall, Proc Natl Acad Sci USA 1997 94 14736 14741 9405682 10.1073/pnas.94.26.14736
4. DJ Weatherall JB Clegg, The thalassaemia syndromes London: Blackwell Science Ltd 4 2001
5. Evolutionary and historical aspects of the burden of malaria. R Carter KN Mendis, Clin Microbiol Rev 2002 15 564 594 12364370 10.1128/CMR.15.4.564-594. 2002
6. Effects of partial inbreeding on fixation rates and variation of mutant genes. A Caballero GW Hill, Genetics 1992 131 493 507 1644283
7. Consanguinity affects selection of alpha-thalassemia genotypes and the size of populations under selection pressure from malaria. S Denic C Frampton N Nagelkerke MG Nicholls, Ann Hum Biol 2007 34 620 631 10.1080/03014460701615993 18092206
8. A Alwan B Modell, Community Control of Genetic and Congenital Disorders WHO: EMRO Technical Publications Series 1997
9. Endogamy in the Arab world. M Khlat, Genetic Disorders among Arab Populations New York: Oxford University Press, Teebi AS, Farag TI, 1997 63 80
10. J Diamond, Guns, germs, and steel: the fates of human societies New York: WW Norton & Co. Inc 1997
11. BD Smith, The emergence of agriculture New York: Scientific American Library 1995
12. A study of some genetic characteristics of the Fur and Baggara tribes of the Sudan. RA Bayoumi TSM Taha N Saha, Am J Phys Anthrop 1985 67 363 370 10.1002/ajpa.1330670408 2932917
13. The costs of human inbreeding and their implications for variations at the DNA level. HA Bittles JV Neel, Nature Genet 1994 8 117 121 10.1038/ng1094-117 7842008
14. JH Gillespie, Population Genetics: A Concise Guide Baltimore: The John Hopkins Univ. Press 1998
15. Consanguineous marriages in the United Arab Emirates. LI Al-Gazali A Bener YM Abdulrazzaq R Micallef AI Al-Khayat T Gaber, J Biosoc Sci 1997 29 491 497 10.1017/S0021932097004914 9881148
16. Hemoglobinopathies in the United Arab Emirates. E Baysal, Hemoglobin 2001 25 247 253 10.1081/HEM-100104033 11480786
17. Religious differentials in postfamine marriage patterns, Northern Ireland, 1840-1915. I. Demographic and isonymy analysis. AH Bittles MT Smith, Hum Biol 1994 66 59 76 8157265
18. Inbreeding in Escazu, Costa Rica (1800-1840, 1850-1899): isonymy and ecclesiastical dispensations. L Madrigal B Ware, Hum Biol 1997 69 703 714 9299889
19. Consanguinity decreases risk of breast cancer - cervical cancer unaffected. S Denic A Bener, Br J Cancer 2001 85 1675 1679 10.1054/bjoc.2001. 2131 11742487
20. Lay perception of genetic risks attributable to inbreeding in Pakistan. R Hussain, Am J Hum Biol 2002 14 264 274 10.1002/ajhb.10034 11891938
21. M Piattelli-Palmarini, Inevitable Illusions: How Mistakes of Reason Rule our Minds New York: John Wiley & Sons 1994
22. Peopling of India. M Gadgil NV Joshi UV Shambu Prasad S Manoharan S Patil, The Indian Human Heritage Hyderabad: Univ. Press, Balasubramanian D, Appaji Rao N, 1997 100 129
23. The bases of Western attitudes to consanguineous marriage. AH Bittles, Dev Med Child Neurol 2003 45 135 138 12578240
24. An association between the kinship and fertility of human couples. A Helgason S Palsson DF Guobjartsson P Kristjansson K Sefansson, Science 2008 319 813 816 10.1126/science.1150232 18258915
25. A functional promoter polymorphism in monocyte chemoattractant protein-1 is associated with increased susceptibility to pulmonary tuberculosis. PO Flores-Villanueva JA Ruiz-Morales CH Song LM Flores EK Jo M Montano PF Barnes M Selman J Granados, J Exp Med 2005 202 1649 1658 16352737 10.1084/jem.20050126
26. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study. MW Smith M Dean M Carrington C Winkler GA Huttley DA Lomb JJ Goedert TR O'Brien LP Jacobson R Kaslow S Buchbinder E Vittinghoff D Vlahov K Hoots MW Hilgartner SJ O'Brien, Science 1997 277 959 965 10.1126/science.277.5328.959 9252328