Current status of thrombolytics-the need for better, especially safer, agents

Thrombosis Research

Volumn 122, Issue SUPPL. 3, 2008, Pages

  White II, Gilbert C ^a  

^a BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOLYTIC AGENT; PLASMIN; PLASMINOGEN ACTIVATOR;

ACUTE CORONARY SYNDROME; ARTERY EMBOLISM; ARTICLE; BLEEDING; BRAIN HEMORRHAGE; CEREBROVASCULAR ACCIDENT; DEEP VEIN THROMBOSIS; DRUG SAFETY; FIBRINOLYSIS; HEART INFARCTION; HOSPITAL ADMISSION; HUMAN; INCIDENCE; MORTALITY; PREVALENCE; PRIORITY JOURNAL;

FIBRINOLYTIC AGENTS; HUMANS; THROMBOSIS;

EID: 50849135517     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2008.06.008     Document Type: Article

References (7)

1. Fowkes F.J., Price J.F., and Fowkes F.G. Incidence of diagnosed deep vein thrombosis in the general population: systematic review. Eur J Vasc Endovasc Surg 25 (2003) 1-5
2. White R.H. The epidemiology of venous thromboembolism. Circulation 107 (2003) I4-I8
3. Rosamond W., Flegal K., Friday G., et al. Heart disease and stroke statistics-2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 115 (2007) e69-e171
4. Alkjaersig N., Fletcher A.P., and Sherry S. The mechanism of clot dissolution by plasmin. J Clin Invest 38 (1959) 1086-1095
5. Verstraete M. Biochemical and clinical aspects of thrombolysis. Semin Hematol 15 (1978) 35-54
6. Marder V.J. The use of thrombolytic agents: choice of patient, drug administration, laboratory monitoring. Ann Intern Med 90 (1979) 802-808
7. Marder V.J., Landskroner K., Novokhatny V., et al. Plasmin induces local thrombolysis without causing hemorrhage: a comparison with tissue plasminogen activator in the rabbit. Thromb Haemost 86 (2001) 739-745