-
1
-
-
0029121925
-
Gene targeting and gene transfer studies of the biological role of the plasminogen/plasmin system
-
Carmeliet P., and Collen D. Gene targeting and gene transfer studies of the biological role of the plasminogen/plasmin system. Thromb Haemost 74 1 (Jul 1995) 429-436
-
(1995)
Thromb Haemost
, vol.74
, Issue.1
, pp. 429-436
-
-
Carmeliet, P.1
Collen, D.2
-
2
-
-
0018817278
-
Localization of individual lysine-binding regions in human plasminogen and investigation on their complex-forming properties
-
Lerch P.G., Rickli E.E., Lergier W., and Gillessen D. Localization of individual lysine-binding regions in human plasminogen and investigation on their complex-forming properties. Eur J Biochem 107 (1980) 7-13
-
(1980)
Eur J Biochem
, vol.107
, pp. 7-13
-
-
Lerch, P.G.1
Rickli, E.E.2
Lergier, W.3
Gillessen, D.4
-
3
-
-
0020596647
-
The binding of human plasminogen to fibrin and fibrinogen
-
Lucas M.A., Fretto L.J., and McKee P.A. The binding of human plasminogen to fibrin and fibrinogen. J Biol Chem 258 (1983) 4249-4256
-
(1983)
J Biol Chem
, vol.258
, pp. 4249-4256
-
-
Lucas, M.A.1
Fretto, L.J.2
McKee, P.A.3
-
4
-
-
0018101441
-
On the kinetics of the reaction between human antiplasmin and plasmin
-
Wiman B., and Collen D. On the kinetics of the reaction between human antiplasmin and plasmin. Eur J Biochem 84 (1978) 573-582
-
(1978)
Eur J Biochem
, vol.84
, pp. 573-582
-
-
Wiman, B.1
Collen, D.2
-
5
-
-
0017102105
-
Isolation and characterization of alpha2-plasmin inhibitor from human plasma. A novel proteinase inhibitor which inhibits activator-induced clot lysis
-
Moroi M., and Aoki N. Isolation and characterization of alpha2-plasmin inhibitor from human plasma. A novel proteinase inhibitor which inhibits activator-induced clot lysis. J Biol Chem 251 (1978) 5956-5965
-
(1978)
J Biol Chem
, vol.251
, pp. 5956-5965
-
-
Moroi, M.1
Aoki, N.2
-
6
-
-
0017082215
-
Identification and some properties of a new fast-reacting plasmin inhibitor in human plasma
-
Collen D. Identification and some properties of a new fast-reacting plasmin inhibitor in human plasma. Eur J Biochem 69 (1976) 209-216
-
(1976)
Eur J Biochem
, vol.69
, pp. 209-216
-
-
Collen, D.1
-
7
-
-
0010470125
-
Physicochemical studies on human plasminogen (profibrinolysin) and plasmin (fibrinolysin)
-
Shulman S., Alkjaersig N., and Sherry S. Physicochemical studies on human plasminogen (profibrinolysin) and plasmin (fibrinolysin). J Biol Chem 233 1 (Jul 1958) 91-97
-
(1958)
J Biol Chem
, vol.233
, Issue.1
, pp. 91-97
-
-
Shulman, S.1
Alkjaersig, N.2
Sherry, S.3
-
8
-
-
50849115693
-
In vivo fibrinolytic activity and pharmacology of various plasmin (fibrinolysin) preparations
-
Back N., Ambrus J.L., Goldstein S., and Harrisson J.W. In vivo fibrinolytic activity and pharmacology of various plasmin (fibrinolysin) preparations. Circ Res 4 4 (Jul 1956) 440-443
-
(1956)
Circ Res
, vol.4
, Issue.4
, pp. 440-443
-
-
Back, N.1
Ambrus, J.L.2
Goldstein, S.3
Harrisson, J.W.4
-
9
-
-
50849090834
-
Clinical studies on an activator free porcine plasmin (plasmin-novo)
-
Amris C.j., Larsen V., Mogensen B., and Storm O. Clinical studies on an activator free porcine plasmin (plasmin-novo). Sangre (Barc) 61 (1964) 12-18
-
(1964)
Sangre (Barc)
, vol.61
, pp. 12-18
-
-
Amris, C.j.1
Larsen, V.2
Mogensen, B.3
Storm, O.4
-
11
-
-
50849137404
-
Enzymatic properties of bovine plasmin preparations; evidence for similarity to but non-identity with trypsin
-
Ronwin E. Enzymatic properties of bovine plasmin preparations; evidence for similarity to but non-identity with trypsin. Can J Biochem Physiol 34 6 (Nov 1956) 1169-1183
-
(1956)
Can J Biochem Physiol
, vol.34
, Issue.6
, pp. 1169-1183
-
-
Ronwin, E.1
-
12
-
-
0029160127
-
The fibrinolytic system: from Petri dishes to genetic engineering
-
Verstraete M. The fibrinolytic system: from Petri dishes to genetic engineering. Thromb Haemost 74 1 (Jul 1995) 25-35
-
(1995)
Thromb Haemost
, vol.74
, Issue.1
, pp. 25-35
-
-
Verstraete, M.1
-
13
-
-
0842325566
-
Effects of intravenous administration of fibrinolysin (plasmin) in man
-
Moser K.M. Effects of intravenous administration of fibrinolysin (plasmin) in man. Circulation 20 (1959) 42-55
-
(1959)
Circulation
, vol.20
, pp. 42-55
-
-
Moser, K.M.1
-
14
-
-
0842282389
-
Clinical pharmacology of various types of fibrinolytic enzyme preparation
-
Ambrus J.L., Ambrus C.M., Sokal J.E., et al. Clinical pharmacology of various types of fibrinolytic enzyme preparation. Am J Cardiol 6 (1960) 462-475
-
(1960)
Am J Cardiol
, vol.6
, pp. 462-475
-
-
Ambrus, J.L.1
Ambrus, C.M.2
Sokal, J.E.3
-
15
-
-
0842282392
-
Review of clinical experience with clotlysing agents
-
Cliffton E.E. Review of clinical experience with clotlysing agents. Am J Cardiol 6 (1960) 476-486
-
(1960)
Am J Cardiol
, vol.6
, pp. 476-486
-
-
Cliffton, E.E.1
-
16
-
-
0842347258
-
Treatment of thrombophlebitis with a fibrinolytic agent
-
Davis N.D., Carroll B.J., and Schwartz S.H. Treatment of thrombophlebitis with a fibrinolytic agent. Am J Cardiol 6 (1960) 513-518
-
(1960)
Am J Cardiol
, vol.6
, pp. 513-518
-
-
Davis, N.D.1
Carroll, B.J.2
Schwartz, S.H.3
-
17
-
-
0023498623
-
Isolation by preparative isoelectric focusing of a direct acting fibrinolytic enzyme from the venom of Agkistrodon contortrix contortrix (southern copperhead)
-
Egen N.B., Russell F.E., Sammons D.W., et al. Isolation by preparative isoelectric focusing of a direct acting fibrinolytic enzyme from the venom of Agkistrodon contortrix contortrix (southern copperhead). Toxicon 25 11 (1987) 1189-1198
-
(1987)
Toxicon
, vol.25
, Issue.11
, pp. 1189-1198
-
-
Egen, N.B.1
Russell, F.E.2
Sammons, D.W.3
-
18
-
-
33845304670
-
Alfimeprase: a novel recombinant direct-acting fibrinolytic
-
Deitcher S.R., Funk W.D., Buchanan J., et al. Alfimeprase: a novel recombinant direct-acting fibrinolytic. Expert Opin Biol Ther 6 12 (Dec 2006) 1361-1369
-
(2006)
Expert Opin Biol Ther
, vol.6
, Issue.12
, pp. 1361-1369
-
-
Deitcher, S.R.1
Funk, W.D.2
Buchanan, J.3
-
19
-
-
23844472606
-
A phase I trial of alfimeprase for peripheral arterial thrombolysis
-
Ouriel K., Cynamon J., Weaver F.A., et al. A phase I trial of alfimeprase for peripheral arterial thrombolysis. J Vasc Interv Radiol 16 8 (Aug 2005) 1075-1083
-
(2005)
J Vasc Interv Radiol
, vol.16
, Issue.8
, pp. 1075-1083
-
-
Ouriel, K.1
Cynamon, J.2
Weaver, F.A.3
-
20
-
-
33745995088
-
Phase II trial of alfimeprase, a novel-acting fibrin degradation agent, for occluded central venous access devices
-
Moll S., Kenyon P., Bertoli L., et al. Phase II trial of alfimeprase, a novel-acting fibrin degradation agent, for occluded central venous access devices. J Clin Oncol 24 19 (Jul 1 2006) 3056-3060
-
(2006)
J Clin Oncol
, vol.24
, Issue.19
, pp. 3056-3060
-
-
Moll, S.1
Kenyon, P.2
Bertoli, L.3
-
21
-
-
34247594281
-
Drug evaluation: alfimeprase, a plasminogen-independent thrombolytic
-
Shah A.R., and Scher L. Drug evaluation: alfimeprase, a plasminogen-independent thrombolytic. Drugs 10 (2007) 329-335
-
(2007)
Drugs
, vol.10
, pp. 329-335
-
-
Shah, A.R.1
Scher, L.2
-
22
-
-
50849109724
-
-
Nuvelo Inc Press Release: Nuvelo Announces Phase 2 SONOMA-3 Trial Did Not Meet Target Product Profile and Discontinues Alfimeprase Development. March 17 2008. http://phx.corporate-ir.net/phoenix.zhtml?c = 109749&p=irol-newsArticle&ID=1119462&highlight=.
-
Nuvelo Inc Press Release: Nuvelo Announces Phase 2 SONOMA-3 Trial Did Not Meet Target Product Profile and Discontinues Alfimeprase Development. March 17 2008. http://phx.corporate-ir.net/phoenix.zhtml?c = 109749&p=irol-newsArticle&ID=1119462&highlight=.
-
-
-
-
23
-
-
0141673321
-
Recombinant human microplasmin: production and potential therapeutic properties
-
Nagai N., Demarsin E., Van Hoef B., et al. Recombinant human microplasmin: production and potential therapeutic properties. J Thromb Haemost 1 (2003) 307-313
-
(2003)
J Thromb Haemost
, vol.1
, pp. 307-313
-
-
Nagai, N.1
Demarsin, E.2
Van Hoef, B.3
-
24
-
-
0032560642
-
Fibrinolysis with des-kringle derivatives of plasmin and its modulation by plasma protease inhibitors
-
Komorowicz E., Kolev K., and Machovich R. Fibrinolysis with des-kringle derivatives of plasmin and its modulation by plasma protease inhibitors. Biochemistry 37 (1998) 9112-9118
-
(1998)
Biochemistry
, vol.37
, pp. 9112-9118
-
-
Komorowicz, E.1
Kolev, K.2
Machovich, R.3
-
25
-
-
50849102203
-
-
ThromboGenics NV announces update on its microplasmin development strategy for peripheral vascular disease. ThromboGenics NV. http://www.thrombogenics.com/documents/06_TG_10PAOD_DVTENGFINAL.pdf. August 28, 2007.
-
ThromboGenics NV announces update on its microplasmin development strategy for peripheral vascular disease. ThromboGenics NV. http://www.thrombogenics.com/documents/06_TG_10PAOD_DVTENGFINAL.pdf. August 28, 2007.
-
-
-
-
26
-
-
0942298146
-
Posterior vitreous detachment induced by microplasmin
-
Gandorfer A., Rohleder M., Sethi C., et al. Posterior vitreous detachment induced by microplasmin. Invest Ophthalmol Vis Sci 45 2 (Feb 2004) 641-647
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, Issue.2
, pp. 641-647
-
-
Gandorfer, A.1
Rohleder, M.2
Sethi, C.3
-
27
-
-
50849099695
-
Production and characterization of a novel, recombinantly-modified plasmin molecule
-
Hunt J., and Novokhatny V. Production and characterization of a novel, recombinantly-modified plasmin molecule. J Thromb Haemost 3 Suppl 1 (2005) P0781
-
(2005)
J Thromb Haemost
, vol.3
, Issue.SUPPL. 1
-
-
Hunt, J.1
Novokhatny, V.2
-
28
-
-
50849086956
-
-
Hunt J, Petteway S, Scuderi P, et al. Simplified recombinant plasmin: production and functional comparison of a novel thrombolytic molecule with full-length plasmin. Thromb Haemost [In Press].
-
Hunt J, Petteway S, Scuderi P, et al. Simplified recombinant plasmin: production and functional comparison of a novel thrombolytic molecule with full-length plasmin. Thromb Haemost [In Press].
-
-
-
-
29
-
-
0026533894
-
The amount of plasminogen, tissue-type plasminogen activator and plasminogen activator inhibitor type 1 in human thrombi and the relation to ex-vivo lysibility
-
Potter van Loon B.J., Rijken D.C., Brommer E.J., and van der Maas A.P. The amount of plasminogen, tissue-type plasminogen activator and plasminogen activator inhibitor type 1 in human thrombi and the relation to ex-vivo lysibility. Thromb Haemost 67 (1992) 101-105
-
(1992)
Thromb Haemost
, vol.67
, pp. 101-105
-
-
Potter van Loon, B.J.1
Rijken, D.C.2
Brommer, E.J.3
van der Maas, A.P.4
-
30
-
-
0030050197
-
Proteins of the fibrinolytic system in human thrombi
-
Robbie L.A., Bennett B., Croll A.M., et al. Proteins of the fibrinolytic system in human thrombi. Thromb Haemost 75 (1996) 127-133
-
(1996)
Thromb Haemost
, vol.75
, pp. 127-133
-
-
Robbie, L.A.1
Bennett, B.2
Croll, A.M.3
-
31
-
-
0842282394
-
Thrombolytic potency of acid-stabilized plasmin: superiority over tissue-type plasminogen activator in an in vitro model of catheter-assisted thrombolysis
-
Novokhatny V., Taylor K., and Zimmerman T.P. Thrombolytic potency of acid-stabilized plasmin: superiority over tissue-type plasminogen activator in an in vitro model of catheter-assisted thrombolysis. J Thromb Haemost 1 5 (May 2003) 1034-1041
-
(2003)
J Thromb Haemost
, vol.1
, Issue.5
, pp. 1034-1041
-
-
Novokhatny, V.1
Taylor, K.2
Zimmerman, T.P.3
-
32
-
-
0842266263
-
Locally delivered plasmin: why should it be superior to plasminogen activators for direct thrombolysis?
-
Novokhatny V.V., Jesmok G.J., Landskroner K.A., et al. Locally delivered plasmin: why should it be superior to plasminogen activators for direct thrombolysis?. Trends Pharmacol Sci 25 2 (Feb 2004) 72-75
-
(2004)
Trends Pharmacol Sci
, vol.25
, Issue.2
, pp. 72-75
-
-
Novokhatny, V.V.1
Jesmok, G.J.2
Landskroner, K.A.3
-
33
-
-
0037944134
-
Distinct dose-dependent effects of plasmin and TPA on coagulation and hemorrhage
-
Stewart D., Kong M., Novokhatny V., Jesmok G., and Marder V.J. Distinct dose-dependent effects of plasmin and TPA on coagulation and hemorrhage. Blood 101 8 (2003) 3002-3007
-
(2003)
Blood
, vol.101
, Issue.8
, pp. 3002-3007
-
-
Stewart, D.1
Kong, M.2
Novokhatny, V.3
Jesmok, G.4
Marder, V.J.5
-
34
-
-
0029950898
-
Fibrolase, an active thrombolytic enzyme in arterial and venous thrombosis model systems
-
Markland F.S. Fibrolase, an active thrombolytic enzyme in arterial and venous thrombosis model systems. Adv Exp Med Biol 391 (1996) 427-438
-
(1996)
Adv Exp Med Biol
, vol.391
, pp. 427-438
-
-
Markland, F.S.1
-
35
-
-
0035742236
-
Alfimeprase: pharmacology of a novel fibrinolytic metalloproteinase for thrombolysis
-
Toombs C.F. Alfimeprase: pharmacology of a novel fibrinolytic metalloproteinase for thrombolysis. Haemostasis 31 (2001) 141-147
-
(2001)
Haemostasis
, vol.31
, pp. 141-147
-
-
Toombs, C.F.1
-
36
-
-
0034852601
-
Plasmin induces local thrombolysis without causing hemorrhage: a comparison with tissue plasminogen activator in the rabbit
-
VJ, Landskroner K., Novokhatny V., Zimmerman T.P., Kong M., Kanouse J.J., and Jesmok G. Plasmin induces local thrombolysis without causing hemorrhage: a comparison with tissue plasminogen activator in the rabbit. Thromb Haemost 86 3 (2001) 739-745
-
(2001)
Thromb Haemost
, vol.86
, Issue.3
, pp. 739-745
-
-
VJ1
Landskroner, K.2
Novokhatny, V.3
Zimmerman, T.P.4
Kong, M.5
Kanouse, J.J.6
Jesmok, G.7
-
37
-
-
43749084383
-
-
Shlansky-Goldberg RD, Matsumoto AH, Baumbach GA, Siegel JB, Raabe RD, Murphy TP, Deng C, Dawkins JR, Marder VJ. A first-in-human phase I trial of locally delivered human plasmin for hemodialysis graft occlusion. J Thromb Haemost 2008 Apr 2;in press.
-
Shlansky-Goldberg RD, Matsumoto AH, Baumbach GA, Siegel JB, Raabe RD, Murphy TP, Deng C, Dawkins JR, Marder VJ. A first-in-human phase I trial of locally delivered human plasmin for hemodialysis graft occlusion. J Thromb Haemost 2008 Apr 2;in press.
-
-
-
|