Ion-ion reactions with fixed-charge modified proteins to produce ions in a single, very high charge state

International Journal of Mass Spectrometry

Volumn 276, Issue 2-3, 2008, Pages 136-143

  Frey, Brian L ^a   Krusemark, Casey J ^a   Ledvina, Aaron R ^a   Coon, Joshua J ^a   Belshaw, Peter J ^a   Smith, Lloyd M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Derivatized protein; High charge state; Ion attachment; Ion parking; Ion ion reaction

Indexed keywords

EID: 50849124752     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2008.07.029     Document Type: Article

References (36)

1. Wang G., and Cole R.B. Solution, gas-phase, and instrumental parameter influences on charge-state distributions in electrospray ionization mass spectrometry. In: Cole R.B. (Ed). Electrospray Ionization Mass Spectrometry (1997), Wiley, New York 137
2. Iavarone A.T., and Williams E.R. J. Am. Chem. Soc. 125 (2003) 2319
3. McLuckey S.A., Vanberkel G.J., and Glish G.L. J. Am. Chem. Soc. 112 (1990) 5668
4. Ikonomou M.G., and Kebarle P. Int. J. Mass Spectrom. Ion Process. 117 (1992) 283
5. Loo R.R.O., and Smith R.D. J. Am. Soc. Mass Spectrom. 5 (1994) 207
6. Catalina M.I., van den Heuvel R.H.H., van Duijn E., and Heck A.J.R. Chem. Eur. J. 11 (2005) 960
7. McLuckey S.A., and Stephenson Jr. J.L. Mass Spectrom. Rev. 17 (1998) 369
8. Pitteri S.J., and McLuckey S.A. Mass Spectrom. Rev. 24 (2005) 931
9. Scalf M., Westphall M.S., Krause J., Kaufman S.L., and Smith L.M. Science 283 (1999) 194
10. Scalf M., Westphall M.S., and Smith L.M. Anal. Chem. 72 (2000) 52
11. Frey B.L., Lin Y., Westphall M.S., and Smith L.M. J. Am. Soc. Mass Spectrom. 16 (2005) 1876
12. Reid G.E., Shang H., Hogan J.M., Lee G.U., and McLuckey S.A. J. Am. Chem. Soc. 124 (2002) 7353
13. McLuckey S.A., Reid G.E., and Wells J.M. Anal. Chem. 74 (2002) 336
14. He M., and McLuckey S.A. J. Am. Chem. Soc. 125 (2003) 7756
15. He M., and McLuckey S.A. Anal. Chem. 76 (2004) 4189
16. Gunawardena H.P., Emory J.F., and McLuckey S.A. Anal. Chem. 78 (2006) 3788
17. Budnik B.A., and Zubarev R.A. Chem. Phys. Lett. 316 (2000) 19
18. Hvelplund P., Nielsen S.B., Sorensen M., Andersen J.U., and Jorgensen T.J.D. J. Am. Soc. Mass Spectrom. 12 (2001) 889
19. Iavarone A.T., Jurchen J.C., and Williams E.R. Anal. Chem. 73 (2001) 1455
20. Sze S.K., Ge Y., Oh H., and McLafferty F.W. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 1774
21. Stephenson Jr. J.L., Van Berkel G.J., and McLuckey S.A. J. Am. Soc. Mass Spectrom. 8 (1997) 637
22. Smith R.D., Loo J.A., Loo R.R.O., Busman M., and Udseth H.R. Mass Spectrom. Rev. 10 (1991) 359
23. Iavarone A.T., Paech K., and Williams E.R. Anal. Chem. 76 (2004) 2231
24. Good D.M., Wirtala M., McAlister G.C., and Coon J.J. Mol. Cell. Proteomics 6 (2007) 1942
25. Kelleher N.L. Anal. Chem. 76 (2004) 196A
26. Reid G.E., Wu J., Chrisman P.A., Wells J.M., and McLuckey S.A. Anal. Chem. 73 (2001) 3274
27. Syka J.E.P., Coon J.J., Schroeder M.J., Shabanowitz J., and Hunt D.F. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 9528
28. Krusemark C.J., Ferguson J.T., Wenger C.D., Kelleher N.L., and Belshaw P.J. Anal. Chem. 80 (2008) 713
29. Coon J.J., Ueberheide B., Syka J.E.P., Dryhurst D.D., Ausio J., Shabanowitz J., and Hunt D.F. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 9463
30. Coon J.J., Syka J.E.P., Schwartz J.C., Shabanowitz J., and Hunt D.F. Int. J. Mass Spectrom. 236 (2004) 33
31. Gunawardena H.P., He M., Chrisman P.A., Pitteri S.J., Hogan J.M., Hodges B.D.M., and McLuckey S.A. J. Am. Chem. Soc. 127 (2005) 12627
32. Stephenson Jr. J.L., and McLuckey S.A. Anal. Chem. 69 (1997) 281
33. Verkerk U.H., and Kebarle P. J. Am. Soc. Mass Spectrom. 16 (2005) 1325
34. Hunter E.P., and Lias S.G. NIST standard reference database number 69. In: Mallard W.G., and Lindstrom P.J. (Eds). NIST Chemistry Webbook (2005), National Institute of Standards and Technology, Gaithersburg, MD. http://webbook.nist.gov/chemistry
35. The gas-phase basicities (GB) of model compounds were obtained from the NIST Chemistry Webbook, Ref. [35]. The model compounds (and GB values in kJ/mol) included deprotonated anions of the following: phenol (1430), acetamide (1485), and methyl acetamide (1483). These values give an indication of the energy required to deprotonate the following parts of a protein: tyrosine, asparagine/glutamine, and the amide backbone, respectively. For comparison, the carboxylate group of glycine has a GB of 1430 kJ/mol.
36. Stephenson Jr. J.L., and McLuckey S.A. J. Am. Chem. Soc. 118 (1996) 7390