A second disulfide bridge from the N-terminal domain to extracellular loop 2 dampens receptor activity in GPR39

Biochemistry

Volumn 47, Issue 35, 2008, Pages 9198-9207

  Storjohann, Laura ^a   Holst, Birgitte ^a   Schwartz, Thue W ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b 7TM Pharma A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER NETWORKS; LABELING; ZINC;

CYS RESIDUES; DISULFIDE BRIDGES; EXTRACELLULAR LOOP 2;

BRIDGES;

CYSTEINE; DISULFIDE; GPR39 RECEPTOR; GROWTH HORMONE SECRETAGOGUE RECEPTOR; UNCLASSIFIED DRUG; ZINC;

AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SENSOR;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; CELLS, CULTURED; CYSTEINE; DISULFIDES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE ALIGNMENT;

EID: 50849106067     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8005016     Document Type: Article

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