More good reasons for adherence to statin therapy during acute coronary syndromes

European Heart Journal

Volumn 29, Issue 17, 2008, Pages 2061-2063

  Herrler, Tanja ^a   Böhm, Michael ^b   Heeschen, Christopher ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MATRIX METALLOPROTEINASE INHIBITOR; NITRIC OXIDE; PADGEM PROTEIN; PLACENTAL GROWTH FACTOR; RHO FACTOR; SIMVASTATIN; TISSUE PLASMINOGEN ACTIVATOR;

ACUTE CORONARY SYNDROME; ACUTE HEART INFARCTION; ANTIINFLAMMATORY ACTIVITY; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL FUNCTION; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; DRUG INDICATION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; EDITORIAL; ENZYME INHIBITION; FOLLOW UP; HEART PROTECTION; HUMAN; LOW DRUG DOSE; MACROPHAGE ACTIVATION; MORBIDITY; MORTALITY; PATIENT COMPLIANCE; PRIORITY JOURNAL; RISK REDUCTION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOSIS; TREATMENT RESPONSE;

FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MYOCARDIAL INFARCTION;

EID: 50849091594     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehn348     Document Type: Editorial

References (15)

1. SSSS. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994;344:1383-1389.
2. Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, MacFarlane PW, McKillop JH, Packard CJ. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med 1995;333:1301-1307.
3. Vaughan CJ, Murphy MB, Buckley BM. Statins do more than just lower cholesterol. Lancet 1996;348:1079-1082.
4. Weis M, Heeschen C, Glassford AJ, Cooke JP. Statins have biphasic effects on angiogenesis. Circulation 2002;105:739-745.
5. Sacks FM. Do statins play a role in the early management of the acute coronary syndrome? Eur Heart J 2008;6:A32-A36.
6. Kamal-Bahl SJ, Burke T, Watson D, Wentworth C. Discontinuation of lipid modifying drugs among commercially insured United States patients in recent clinical practice. Am J Cardiol 2007;99:530-534.
7. Laufs U, Endres M, Custodis F, Gertz K, Nickenig G, Liao JK, Bohm M. Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription. Circulation 2000;102:3104-3110.
8. Thomas M, Mann J. Increased thrombotic vascular events after change of statin. [Letter]. Lancet 1998;352:1830-1831.
9. PRISM. A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina. Platelet Receptor Inhibition in Ischemic Syndrome Management (PRISM) Study Investigators. N Engl J Med 1998;338: 1498-1505.
10. McGowan MP. There is no evidence for an increase in acute coronary syndromes after short-term abrupt discontinuation of statins in stable cardiac patients. Circulation 2004;110:2333-2335.
11. Fonarow GC, Wright RS, Spencer FA, Fredrick PD, Dong W, Every N, French WJ. Effect of statin use within the first 24 hours of admission for acute myocardial infarction on early morbidity and mortality. Am J Cardiol 2005;96:611-616.
12. Spencer FA, Fonarow GC, Frederick PD, Wright RS, Every N, Goldberg RJ, Gore JM, Dong W, Becker RC, French W. Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarction. Arch Intern Med 2004;164:2162-2168.
13. Daskalopoulou SS, Delaney JAC, Filion KB, Brophy JM, Mayo NE, Suissa S. Discontinuation of statin therapy following an acute myocardial infarction: a population-based study. Eur Heart J 2008;29:2083-2091. First published on July 29, 2008. doi:10.1093/eurheartj/ehn346.
14. Blanco M, Nombela F, Castellanos M, Rodriguez-Yáñez M, García-Gil M, Leira R, Lizasoain I, Serena J, Vivancos J, Moro MA, Dávalos A, Castillo J. Statin treatment withdrawal in ischemic stroke: a controlled randomized study. Neurology 2007;69:904-910.
15. Heeschen C, Dimmeler S, Fichtlscherer S, Hamm CW, Berger J, Simoons ML, Zeiher AM. Prognostic value of placental growth factor in patients with acute chest pain. JAMA 2004;291:435-441.