Evaluation of killing kinetics of anti-tuberculosis drugs on Mycobacterium tuberculosis using a bacteriophage-based assay

Chemotherapy

Volumn 54, Issue 5, 2008, Pages 404-411

  Marcel, Nimi ^a   Nahta, Ajay ^a   Balganesh, Meenakshi ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Drug discovery; Ethambutol; Killing kinetics; Phage based assay evaluation; Streptomycin

Indexed keywords

ETHAMBUTOL; ISONIAZID; MOXIFLOXACIN; RIFAMPICIN; STREPTOMYCIN; TUBERCULOSTATIC AGENT;

ARTICLE; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIOPHAGE; CLINICAL PROTOCOL; COLONY FORMING UNIT; CONCENTRATION RESPONSE; DRUG MECHANISM; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PLAQUE FORMING CELL; PRIORITY JOURNAL;

ANTITUBERCULAR AGENTS; BACTERIOPHAGES; KINETICS; MICROBIAL VIABILITY; MYCOBACTERIUM TUBERCULOSIS;

EID: 50849088964     PISSN: 00093157     EISSN: None     Source Type: Journal    
DOI: 10.1159/000153314     Document Type: Article

References (14)

1. Craig WA: Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 1998;26:1-12.
2. Al-Lahham A, Reinert RR: Time-kill kinetics of Streptococcus pneumoniae with reduced susceptibility to telithromycin. Chemotherapy 2007;53:190-193.
3. Odenholt I, Walder M, Wullt M: Pharmacodynamic studies of vancomycin, metronidazole and fusidic acid against Clostridium difficile. Chemotherapy 2007;53:267-274.
4. Balganesh TS, Balasubramanian V, Anand Kumar S: Drug discovery for tuberculosis: bottlenecks and path forward. Curr Sci 2004; 86:167-176.
5. Eltringham IJ, Wilson SM, Drobniewski FA: Evaluation of a bacteriophage-based assay (phage amplified biologically assay) as a rapid screen for resistance to isoniazid, ethambutol, streptomycin, pyrazinamide and ciprofloxacin among clinical isolates of Mycobacterium tuberculosis. J Clin Microbiol 1999;37:3528-3532.
6. McNerney R, Mallard K, Honorathy MRU, Lemma E, Donoghue HD: Colorimetric phage-based assay for detection of rifampicin-resistant Mycobacterium tuberculosis. J Clin Microbiol 2007;45:1330-1332.
7. McNerney R, Kambashi BS, Kinkese J, Tembwe R, Godfrey-Faussett P: Development of a bacteriophage replication assay for diagnosis of pulmonary tuberculosis. J Clin Microbiol 1999;42:2115-2120.
8. McNerney R, Wilson SM, Sidhu AM, Harley VM, Nye PM, Parish T, Stoker NG: Inactivation of mycobacteriophage D29 using ferrous ammonium sulphate as a tool for the detection of viable Mycobacterium smegmatis and M. tuberculosis. Res Microbiol 1998;149:487-495.
9. Jayaram R, Gaonkar S, Kaur P, Suresh BL, Mahesh BN, Jayashree R, Nandi V, Bharat S, Shandil RK, Kantharaj E, Balasubramanian V: Pharmacokinetics- pharmacodynamics of rifampin in an aerosol infection model of tuberculosis. Antimicrob Agents Chemother 2003;47:2118-2124.
10. Jayaram R, Shandil RK, Gaonkar S, Kaur P, Suresh BL, Mahesh BN, Jayashree R, Nandi V, Bharath S, Kantharaj E, Balasubramanian V: Isoniazid pharmacokinetics-pharmacodynamics in an aerosol infection model of tuberculosis. Antimicrob Agents Chemother 2004;48:2951-2957.
11. Shandil RK, Jayaram R, Kaur P, Gaonkar S, Suresh BL, Mahesh BN, Jayashree R, Nandi V, Bharath S, Balasubramanian V: Moxifloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis: evaluation of in vitro and pharmacodynamic indices that best predict in vivo efficacy. Antimicrob Agents Chemother 2007;51:576-582.
12. Scaglione F, Paraboni L: Influence of pharmacokinetics/pharmacodynamics of antibacterials in their dosing regimen selection. Expert Rev Anti Infect Ther 2006;4:479-490.
13. Phillips LM, Sellers MI: Effects of ethambutol, actinomycin D and mitomycin C on the biosynthesis of D29-infected Mycobacterium smegmatis; in Juhasz SE, Plummer G (eds): Host-Virus Relationships in Mycobacterium, Nocardia and Actinomyces. Springfield, Charles C Thomas, 1970, pp 80-102.
14. David HL, Clavel S, Clement F, Pereira JM: Effects of antituberculosis and antileprosy drugs on mycobacteriophage D29 growth. Antimicrob Agents Chemother 1980;18:357-359.