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Volumn 5, Issue 4, 2008, Pages 541-549

Continuous generation of hydrogel beads and encapsulation of biological materials using a microfluidic droplet-merging channel

Author keywords

Droplet merging; Hydrogel beads; Microfluidics

Indexed keywords

BIOLOGICAL MATERIALS; COAGULATION; DROP FORMATION; DROPS; ENCAPSULATION; FLUID MECHANICS; FOOD ADDITIVES; GELATION; GELS; HYDROGELS; MERGING; MIXING; NANOFLUIDICS; OIL WELL PRODUCTION; OPTICAL DESIGN; RATE CONSTANTS;

EID: 50649124464     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-008-0268-6     Document Type: Article
Times cited : (89)

References (40)
  • 1
    • 33747884714 scopus 로고    scopus 로고
    • Production of arrays of chemically distinct nanolitre plugs via repeated splitting in microfluidic devices
    • Adamson DN, Mustafi D, Zhang JXJ, Zheng B, Ismagilov RF (2006) Production of arrays of chemically distinct nanolitre plugs via repeated splitting in microfluidic devices. Lab Chip 6:1178-1186
    • (2006) Lab Chip , vol.6 , pp. 1178-1186
    • Adamson, D.N.1    Mustafi, D.2    Zhang, J.X.J.3    Zheng, B.4    Ismagilov, R.F.5
  • 2
    • 33745613020 scopus 로고    scopus 로고
    • Electrocoalescence of drops synchronized by size-dependent flow in microfluidic channels
    • Ahn K, Agrest J, Chong H, Marquez M, Weitz DA (2006) Electrocoalescence of drops synchronized by size-dependent flow in microfluidic channels. Appl Phys Lett 88:264105
    • (2006) Appl Phys Lett , vol.88 , pp. 264105
    • Ahn, K.1    Agrest, J.2    Chong, H.3    Marquez, M.4    Weitz, D.A.5
  • 3
    • 0037455351 scopus 로고    scopus 로고
    • Formation of dispersions using "flow focusing" in microchannels
    • Anna SL, Bontoux N, Stone HA (2003) Formation of dispersions using "flow focusing" in microchannels. Appl Phys Lett 82:364-366
    • (2003) Appl Phys Lett , vol.82 , pp. 364-366
    • Anna, S.L.1    Bontoux, N.2    Stone, H.A.3
  • 4
    • 18744386937 scopus 로고    scopus 로고
    • Gentle cell trapping and release on a microfluidic chip by in situ alginate hydrogel formation
    • Braschler T, Johann R, Heule M, Metref L, Renaud P (2005) Gentle cell trapping and release on a microfluidic chip by in situ alginate hydrogel formation. Lab Chip 5:553-559
    • (2005) Lab Chip , vol.5 , pp. 553-559
    • Braschler, T.1    Johann, R.2    Heule, M.3    Metref, L.4    Renaud, P.5
  • 5
    • 35649016583 scopus 로고    scopus 로고
    • Generation of monodisperse alginate microbeads and in situ encapsulation of cell in microfluidic device
    • Choi C-H, Jung J-H, Rhee YW, Kim D-P, Shim S-E, Lee C-S (2007) Generation of monodisperse alginate microbeads and in situ encapsulation of cell in microfluidic device. Biomed Microdevices 9:855-862
    • (2007) Biomed Microdevices , vol.9 , pp. 855-862
    • Choi, C.-H.1    Jung, J.-H.2    Rhee, Y.W.3    Kim, D.-P.4    Shim, S.-E.5    Lee, C.-S.6
  • 6
    • 0001567484 scopus 로고
    • Interfacial interactions and the stability of oil-in-water emulsion
    • Dickinson E (1992) Interfacial interactions and the stability of oil-in-water emulsion. Pure Appl Chem 64:1721-1724
    • (1992) Pure Appl Chem , vol.64 , pp. 1721-1724
    • Dickinson, E.1
  • 7
    • 33644777646 scopus 로고    scopus 로고
    • Lab-on-a-chip: Microfluidics in drug discovery
    • Dittrich PS, Manz A (2006) Lab-on-a-chip: Microfluidics in drug discovery. Nat Rev Drug Discov 5:210-218
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 210-218
    • Dittrich, P.S.1    Manz, A.2
  • 8
    • 2442650208 scopus 로고    scopus 로고
    • A synthetic reaction network: Chemical amplification using nonequilibrium autocatalytic reactions coupled in time
    • Gerdts CJ, Sharoyan DE, Ismagilov RF (2004) A synthetic reaction network: Chemical amplification using nonequilibrium autocatalytic reactions coupled in time. J Am Chem Soc 126:6327-6331
    • (2004) J Am Chem Soc , vol.126 , pp. 6327-6331
    • Gerdts, C.J.1    Sharoyan, D.E.2    Ismagilov, R.F.3
  • 9
    • 33846201265 scopus 로고    scopus 로고
    • Multiphase microfluidics: From flow characteristics to chemical and materials synthesis
    • Gunther A, Jensen KF (2006) Multiphase microfluidics: From flow characteristics to chemical and materials synthesis. Lab Chip 6:1487-1503
    • (2006) Lab Chip , vol.6 , pp. 1487-1503
    • Gunther, A.1    Jensen, K.F.2
  • 10
    • 33947669935 scopus 로고    scopus 로고
    • Centrifugal generation and manipulation of droplet emulsions
    • Haeberle S, Zengerle R, Ducree J (2007) Centrifugal generation and manipulation of droplet emulsions. Microfluid Nanofluid 3:65-75
    • (2007) Microfluid Nanofluid , vol.3 , pp. 65-75
    • Haeberle, S.1    Zengerle, R.2    Ducree, J.3
  • 11
    • 0034612266 scopus 로고    scopus 로고
    • Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds
    • Holmes TC, de Lacalle S, Su X, Liu G, Rich A, Zhang S (2000) Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds. Proc Natl Acad Sci USA 97:6728-6733
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6728-6733
    • Holmes, T.C.1    de Lacalle, S.2    Su, X.3    Liu, G.4    Rich, A.5    Zhang, S.6
  • 12
    • 34547691072 scopus 로고    scopus 로고
    • Calcium alginate microcapsule generation on a microfluidic system fabricated using the optical disk process
    • Huang KS, Liu MK, Wu CH, Yen YT, Lin YC (2007) Calcium alginate microcapsule generation on a microfluidic system fabricated using the optical disk process. J Micromech Microeng 17:1428-1434
    • (2007) J Micromech Microeng , vol.17 , pp. 1428-1434
    • Huang, K.S.1    Liu, M.K.2    Wu, C.H.3    Yen, Y.T.4    Lin, Y.C.5
  • 13
    • 33645527584 scopus 로고    scopus 로고
    • Alternating droplet generation and controlled dynamic droplet fusion in microfluidic device for CdS nanoparticle synthesis
    • Hung LH, Choi KM, Tseng WY, Tan YC, Shea KJ, Lee AP (2006) Alternating droplet generation and controlled dynamic droplet fusion in microfluidic device for CdS nanoparticle synthesis. Lab Chip 6:174-178
    • (2006) Lab Chip , vol.6 , pp. 174-178
    • Hung, L.H.1    Choi, K.M.2    Tseng, W.Y.3    Tan, Y.C.4    Shea, K.J.5    Lee, A.P.6
  • 14
    • 18544381896 scopus 로고    scopus 로고
    • Continuous fabrication of biocatalyst immobilized microparticles using photopolymerization and immiscible liquids in microfluidic systems
    • Jeong WJ, Kim JY, Choo J, Lee EK, Han CS, Beebe DJ, Seong GH, Lee SH (2005) Continuous fabrication of biocatalyst immobilized microparticles using photopolymerization and immiscible liquids in microfluidic systems. Langmuir 21:3738-3341
    • (2005) Langmuir , vol.21 , pp. 3738-3741
    • Jeong, W.J.1    Kim, J.Y.2    Choo, J.3    Lee, E.K.4    Han, C.S.5    Beebe, D.J.6    Seong, G.H.7    Lee, S.H.8
  • 15
    • 33846032329 scopus 로고    scopus 로고
    • A microfluidic platform for 3-dimensional cell culture and cell-based assays
    • Kim M, Yeon J, Park J-K (2007) A microfluidic platform for 3-dimensional cell culture and cell-based assays. Biomed Microdevices 9:25-34
    • (2007) Biomed Microdevices , vol.9 , pp. 25-34
    • Kim, M.1    Yeon, J.2    Park, J.-K.3
  • 16
    • 33847342176 scopus 로고    scopus 로고
    • Three-dimensional measurement and visualization of internal flow of a moving droplet using confocal micro-PIV
    • Kinoshita H, Kaneda S, Fujii T, Oshima M (2007) Three-dimensional measurement and visualization of internal flow of a moving droplet using confocal micro-PIV. Lab Chip 7:338-346
    • (2007) Lab Chip , vol.7 , pp. 338-346
    • Kinoshita, H.1    Kaneda, S.2    Fujii, T.3    Oshima, M.4
  • 17
    • 35848959240 scopus 로고    scopus 로고
    • Microphotometric characterization of fluid segment populations generated in different simple microfluidic networks
    • Kohler JM, Groß A (2007) Microphotometric characterization of fluid segment populations generated in different simple microfluidic networks. Microfluid Nanofluid 3:653-663
    • (2007) Microfluid Nanofluid , vol.3 , pp. 653-663
    • Kohler, J.M.1    Groß, A.2
  • 18
    • 34247149835 scopus 로고    scopus 로고
    • Using a multijunction microfluidic device to inject substrate into an array of preformed plugs without cross-contamination: Comparing theory and experiments
    • Li L, Boedicker JQ, Ismagilov RF (2007) Using a multijunction microfluidic device to inject substrate into an array of preformed plugs without cross-contamination: Comparing theory and experiments. Anal Chem 79:2756-2761
    • (2007) Anal Chem , vol.79 , pp. 2756-2761
    • Li, L.1    Boedicker, J.Q.2    Ismagilov, R.F.3
  • 20
    • 33847133913 scopus 로고    scopus 로고
    • Droplet-based synthetic method using microflow focusing and droplet fusion
    • Liu K, Ding H, Chen Y, Zhao XZ (2007) Droplet-based synthetic method using microflow focusing and droplet fusion. Microfluid Nanofluid 3:239-243
    • (2007) Microfluid Nanofluid , vol.3 , pp. 239-243
    • Liu, K.1    Ding, H.2    Chen, Y.3    Zhao, X.Z.4
  • 21
    • 0037789505 scopus 로고    scopus 로고
    • Droplet formation in a microchannel network
    • Nisisako T, Torii T, Higuchi T (2002) Droplet formation in a microchannel network. Lab Chip 2:24-26
    • (2002) Lab Chip , vol.2 , pp. 24-26
    • Nisisako, T.1    Torii, T.2    Higuchi, T.3
  • 22
    • 0035799430 scopus 로고    scopus 로고
    • Patterned colloidal coating using adhesive emulsions
    • Ramos L, Weitz DA (2001) Patterned colloidal coating using adhesive emulsions. Langmuir 17:2275-2277
    • (2001) Langmuir , vol.17 , pp. 2275-2277
    • Ramos, L.1    Weitz, D.A.2
  • 23
    • 14844297001 scopus 로고    scopus 로고
    • Development of mammalian cell-enclosing subsieve-size agarose capsules (<100 μm) for cell therapy
    • Sakai S, Kawabata K, Ono T, Ijima H, Kawakami K (2005) Development of mammalian cell-enclosing subsieve-size agarose capsules (<100 μm) for cell therapy. Biomaterials 26:4786-4792
    • (2005) Biomaterials , vol.26 , pp. 4786-4792
    • Sakai, S.1    Kawabata, K.2    Ono, T.3    Ijima, H.4    Kawakami, K.5
  • 24
    • 44249095844 scopus 로고    scopus 로고
    • Hydrodynamic structures of droplets engineered in rectangular micro-channels
    • doi: 10.1007/s10404-007-0233-9
    • Sarrazin F, Bonometti T, Prat L, Gourdon C, Magnaudet J (2007) Hydrodynamic structures of droplets engineered in rectangular micro-channels. Microfluid Nanofluid. doi: 10.1007/s10404-007-0233-9
    • (2007) Microfluid Nanofluid
    • Sarrazin, F.1    Bonometti, T.2    Prat, L.3    Gourdon, C.4    Magnaudet, J.5
  • 25
    • 4344674322 scopus 로고    scopus 로고
    • Multi-step synthesis of nanoparticles performed on millisecond time scale in a microfluidic droplet-based system
    • Shestopalov I, Tice JD, Ismagilov RF (2004) Multi-step synthesis of nanoparticles performed on millisecond time scale in a microfluidic droplet-based system. Lab Chip 4:316-321
    • (2004) Lab Chip , vol.4 , pp. 316-321
    • Shestopalov, I.1    Tice, J.D.2    Ismagilov, R.F.3
  • 26
    • 34548152794 scopus 로고    scopus 로고
    • Multiphase flow in microfluidic systems: Control and applications of droplets and interfaces
    • Shui L, Eijkel JCT, van den Berg A (2007) Multiphase flow in microfluidic systems: Control and applications of droplets and interfaces. Adv Colloid Interface Sci 133:35-49
    • (2007) Adv Colloid Interface Sci , vol.133 , pp. 35-49
    • Shui, L.1    Eijkel, J.C.T.2    van den Berg, A.3
  • 27
    • 0037450165 scopus 로고    scopus 로고
    • A microfluidic system for controlling reaction networks in time
    • Song H, Tice JD, Ismagilov RF (2003) A microfluidic system for controlling reaction networks in time. Angew Chem Int Ed 42:768-772
    • (2003) Angew Chem Int Ed , vol.42 , pp. 768-772
    • Song, H.1    Tice, J.D.2    Ismagilov, R.F.3
  • 28
    • 33746224336 scopus 로고    scopus 로고
    • On-chip titration of an anticoagulant argatroban and determination of the clotting time within whole blood or plasma using a plug-based microfluidic system
    • Song H, Li HW, Munson MS, Van Ha TG, Ismagilov RF (2006) On-chip titration of an anticoagulant argatroban and determination of the clotting time within whole blood or plasma using a plug-based microfluidic system. Anal Chem 78:4839-4849
    • (2006) Anal Chem , vol.78 , pp. 4839-4849
    • Song, H.1    Li, H.W.2    Munson, M.S.3    Van, Ha.T.G.4    Ismagilov, R.F.5
  • 29
    • 1642351161 scopus 로고    scopus 로고
    • Engineering flows in small devices: Microfluidics toward a lab-on-a-chip
    • Stone HA, Stroock AD, Ajdari A (2004) Engineering flows in small devices: Microfluidics toward a lab-on-a-chip. Ann Rev Fluid Mech 36:381-411
    • (2004) Ann Rev Fluid Mech , vol.36 , pp. 381-411
    • Stone, H.A.1    Stroock, A.D.2    Ajdari, A.3
  • 30
    • 34748901356 scopus 로고    scopus 로고
    • Monodisperse alginate hydrogel microbeads for cell encapsulation
    • Tan WH, Takeuchi S (2007) Monodisperse alginate hydrogel microbeads for cell encapsulation. Adv Mater 19(18):2696-2701
    • (2007) Adv Mater , vol.19 , Issue.18 , pp. 2696-2701
    • Tan, W.H.1    Takeuchi, S.2
  • 31
    • 34347387164 scopus 로고    scopus 로고
    • Droplet coalescence by geometrically mediated flow in microfluidic channels
    • Tan YC, Ho YL, Lee AP (2007) Droplet coalescence by geometrically mediated flow in microfluidic channels. Microfluid Nanofluid 3:495-499
    • (2007) Microfluid Nanofluid , vol.3 , pp. 495-499
    • Tan, Y.C.1    Ho, Y.L.2    Lee, A.P.3
  • 32
    • 4544366400 scopus 로고    scopus 로고
    • Dynamic pattern formation in a vesicle-generating microfluidic device
    • Thorsen T, Roberts RW, Arnold FH, Quake SR (2001) Dynamic pattern formation in a vesicle-generating microfluidic device. Phys Rev Lett 86(18):4163-4166
    • (2001) Phys Rev Lett , vol.86 , Issue.18 , pp. 4163-4166
    • Thorsen, T.1    Roberts, R.W.2    Arnold, F.H.3    Quake, S.R.4
  • 33
    • 0242492537 scopus 로고    scopus 로고
    • Formation of droplets and mixing in multiphase microfluidics at low values of the Reynolds and capillary numbers
    • Tice JD, Song H, Lyon AD, Ismagilov RF (2003) Formation of droplets and mixing in multiphase microfluidics at low values of the Reynolds and capillary numbers. Langmuir 19:9127-9133
    • (2003) Langmuir , vol.19 , pp. 9127-9133
    • Tice, J.D.1    Song, H.2    Lyon, A.D.3    Ismagilov, R.F.4
  • 34
    • 1242351493 scopus 로고    scopus 로고
    • Effects of viscosity on droplet formation and mixing in microfluidic channels
    • Tice JD, Lyon AD, Ismagilov RF (2004) Effects of viscosity on droplet formation and mixing in microfluidic channels. Anal Chim Acta 507:73-77
    • (2004) Anal Chim Acta , vol.507 , pp. 73-77
    • Tice, J.D.1    Lyon, A.D.2    Ismagilov, R.F.3
  • 36
    • 0035340624 scopus 로고    scopus 로고
    • The coalescence of two equal-sized drops in a two-dimensional linear flow
    • Yang H, Park CC, Hu YT, Leal LG (2001) The coalescence of two equal-sized drops in a two-dimensional linear flow. Phys Fluids 13:1087-1106
    • (2001) Phys Fluids , vol.13 , pp. 1087-1106
    • Yang, H.1    Park, C.C.2    Hu, Y.T.3    Leal, L.G.4
  • 37
    • 33746554814 scopus 로고    scopus 로고
    • High-performance flow-focusing geometry for spontaneous generation of monodispersed droplets
    • Yobas L, Martens S, Ong WL, Ranganathan N (2006) High-performance flow-focusing geometry for spontaneous generation of monodispersed droplets. Lab Chip 6:1073-1079
    • (2006) Lab Chip , vol.6 , pp. 1073-1079
    • Yobas, L.1    Martens, S.2    Ong, W.L.3    Ranganathan, N.4
  • 39
    • 18044368667 scopus 로고    scopus 로고
    • A microfluidic approach for screening submicroliter volumes against multiple reagents by using preformed arrays of nanoliter plugs in a three-phase liquid/liquid/gas flow
    • Zheng B, Ismagilov RF (2005) A microfluidic approach for screening submicroliter volumes against multiple reagents by using preformed arrays of nanoliter plugs in a three-phase liquid/liquid/gas flow. Angew Chem Int Ed 44:2520-2523
    • (2005) Angew Chem Int Ed , vol.44 , pp. 2520-2523
    • Zheng, B.1    Ismagilov, R.F.2
  • 40
    • 0043194348 scopus 로고    scopus 로고
    • Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size droplets
    • Zheng B, Roach LS, Ismagilov RF (2003) Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size droplets. J Am Chem Soc 125:11170-11171
    • (2003) J Am Chem Soc , vol.125 , pp. 11170-11171
    • Zheng, B.1    Roach, L.S.2    Ismagilov, R.F.3


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