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Volumn 14, Issue 9, 2008, Pages 1823-1833

Functional and intracellular localization properties of U6 promoter-expressed siRNAs, shRNAs, and chimeric VA1 shRNAs in mammalian cells

Author keywords

Nucleus; PTGS; RNAi; siRNA; Tandem expression vectors

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CHIMERIC PROTEIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

EID: 50649121427     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.1014008     Document Type: Article
Times cited : (7)

References (32)
  • 2
    • 0027122152 scopus 로고
    • Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member
    • Brook, J.D., McCurrach, M.E., Harley, H.G., Buckler, A.J., Church, D., Aburatani, H., Hunter, K., Stanton, V.P., Thirion, J.P., Hudson, T., et al. 1992. Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member. Cell 69: 385.
    • (1992) Cell , vol.69 , pp. 385
    • Brook, J.D.1    McCurrach, M.E.2    Harley, H.G.3    Buckler, A.J.4    Church, D.5    Aburatani, H.6    Hunter, K.7    Stanton, V.P.8    Thirion, J.P.9    Hudson, T.10
  • 3
    • 0033811703 scopus 로고    scopus 로고
    • Downregulation of the CCR5 beta-chemokine receptor and inhibition of HIV-1 infection by stable VA1-ribozyme chimeric transcripts
    • Cagnon, L. and Rossi, J.J. 2000. Downregulation of the CCR5 beta-chemokine receptor and inhibition of HIV-1 infection by stable VA1-ribozyme chimeric transcripts. Antisense Nucleic Acid Drug Dev. 10: 251-261.
    • (2000) Antisense Nucleic Acid Drug Dev , vol.10 , pp. 251-261
    • Cagnon, L.1    Rossi, J.J.2
  • 4
    • 1442360415 scopus 로고    scopus 로고
    • RNase III enzymes and the initiation of gene silencing
    • Carmell, M.A. and Hannon, G.J. 2004. RNase III enzymes and the initiation of gene silencing. Nat. Struct. Mol. Biol. 11: 214-218.
    • (2004) Nat. Struct. Mol. Biol , vol.11 , pp. 214-218
    • Carmell, M.A.1    Hannon, G.J.2
  • 5
    • 0036828639 scopus 로고    scopus 로고
    • The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
    • Carmell, M.A., Xuan, Z., Zhang, M.Q., and Hannon, G.J. 2002. The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes & Dev. 16: 2733-2742.
    • (2002) Genes & Dev , vol.16 , pp. 2733-2742
    • Carmell, M.A.1    Xuan, Z.2    Zhang, M.Q.3    Hannon, G.J.4
  • 6
    • 0030841672 scopus 로고    scopus 로고
    • Expansion of a CUG trinucleotide repeat in the 3′ untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts
    • Davis, B.M., McCurrach, M.E., Taneja, K.L., Singer, R.H., and Housman, D.E. 1997. Expansion of a CUG trinucleotide repeat in the 3′ untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts. Proc. Natl. Acad. Sci. 94: 7388-7393.
    • (1997) Proc. Natl. Acad. Sci , vol.94 , pp. 7388-7393
    • Davis, B.M.1    McCurrach, M.E.2    Taneja, K.L.3    Singer, R.H.4    Housman, D.E.5
  • 7
    • 0037604505 scopus 로고    scopus 로고
    • Functional characterization of the nuclear localization signal for a suppressor of posttranscriptional gene silencing
    • Dong, X., van Wezel, R., Stanley, J., and Hong, Y. 2003. Functional characterization of the nuclear localization signal for a suppressor of posttranscriptional gene silencing. J. Virol. 77: 7026-7033.
    • (2003) J. Virol , vol.77 , pp. 7026-7033
    • Dong, X.1    van Wezel, R.2    Stanley, J.3    Hong, Y.4
  • 8
    • 0037007007 scopus 로고    scopus 로고
    • Using RNA interference to identify genes required for RNA interference
    • Dudley, N.R., Labbe, J.C., and Goldstein, B. 2002. Using RNA interference to identify genes required for RNA interference. Proc. Natl. Acad. Sci. 99: 4191-4196.
    • (2002) Proc. Natl. Acad. Sci , vol.99 , pp. 4191-4196
    • Dudley, N.R.1    Labbe, J.C.2    Goldstein, B.3
  • 9
    • 0037686295 scopus 로고    scopus 로고
    • Killing the messenger: Short RNAs that silence gene expression
    • Dykxhoorn, D.M., Novina, C.D., and Sharp, P.A. 2003. Killing the messenger: Short RNAs that silence gene expression. Nat. Rev. Mol. Cell Biol. 4: 457-467.
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 457-467
    • Dykxhoorn, D.M.1    Novina, C.D.2    Sharp, P.A.3
  • 11
    • 27144544472 scopus 로고    scopus 로고
    • Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster
    • Haussecker, D. and Proudfoot, N.J. 2005. Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster. Mol. Cell. Biol. 25: 9724-9733.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 9724-9733
    • Haussecker, D.1    Proudfoot, N.J.2
  • 12
    • 35748932681 scopus 로고    scopus 로고
    • Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells
    • Hock, J., Weinmann, L., Ender, C., Rudel, S., Kremmer, E., Raabe, M., Urlaub, H., and Meister, G. 2007. Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells. EMBO Rep. 8: 1052-1060.
    • (2007) EMBO Rep , vol.8 , pp. 1052-1060
    • Hock, J.1    Weinmann, L.2    Ender, C.3    Rudel, S.4    Kremmer, E.5    Raabe, M.6    Urlaub, H.7    Meister, G.8
  • 13
    • 33846699083 scopus 로고    scopus 로고
    • A hexanucleotide element directs microRNA nuclear import
    • Hwang, H.W., Wentzel, E.A., and Mendell, J.T. 2007. A hexanucleotide element directs microRNA nuclear import. Science 315: 97-100.
    • (2007) Science , vol.315 , pp. 97-100
    • Hwang, H.W.1    Wentzel, E.A.2    Mendell, J.T.3
  • 14
    • 33748368912 scopus 로고    scopus 로고
    • Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells
    • Kim, D.H., Villeneuve, L.M., Morris, K.V., and Rossi, J.J. 2006. Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat. Struct. Mol. Biol. 13: 793-797.
    • (2006) Nat. Struct. Mol. Biol , vol.13 , pp. 793-797
    • Kim, D.H.1    Villeneuve, L.M.2    Morris, K.V.3    Rossi, J.J.4
  • 15
  • 16
    • 0036256430 scopus 로고    scopus 로고
    • Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
    • Lee, N.S., Dohjima, T., Bauer, G., Li, H., Li, M.J., Ehsani, A., Salvaterra, P., and Rossi, J. 2002. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotechnol. 20: 500-505.
    • (2002) Nat. Biotechnol , vol.20 , pp. 500-505
    • Lee, N.S.1    Dohjima, T.2    Bauer, G.3    Li, H.4    Li, M.J.5    Ehsani, A.6    Salvaterra, P.7    Rossi, J.8
  • 18
    • 40349090024 scopus 로고    scopus 로고
    • miRNA and piRNA localization in the male mammalian meiotic nucleus
    • Marcon, E., Babak, T., Chua, G., Hughes, T., and Moens, P.B. 2008. miRNA and piRNA localization in the male mammalian meiotic nucleus. Chromosome Res. 16: 243-260.
    • (2008) Chromosome Res , vol.16 , pp. 243-260
    • Marcon, E.1    Babak, T.2    Chua, G.3    Hughes, T.4    Moens, P.B.5
  • 19
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus, M.T. and Sharp, P.A. 2002. Gene silencing in mammals by small interfering RNAs. Nat. Rev. Genet. 3: 737-747.
    • (2002) Nat. Rev. Genet , vol.3 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 20
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • Miyagishi, M. and Taira, K. 2002. U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotechnol. 20: 497-500.
    • (2002) Nat. Biotechnol , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 21
    • 4344705410 scopus 로고    scopus 로고
    • Small interfering RNA-induced transcriptional gene silencing in human cells
    • Morris, K.V., Chan, S.W., Jacobsen, S.E., and Looney, D.J. 2004. Small interfering RNA-induced transcriptional gene silencing in human cells. Science 305: 1289-1292.
    • (2004) Science , vol.305 , pp. 1289-1292
    • Morris, K.V.1    Chan, S.W.2    Jacobsen, S.E.3    Looney, D.J.4
  • 22
    • 2342485506 scopus 로고    scopus 로고
    • miRNAs on the move: MiRNA biogenesis and the RNAi machinery
    • Murchison, E.P. and Hannon, G.J. 2004. miRNAs on the move: miRNA biogenesis and the RNAi machinery. Curr. Opin. Cell Biol. 16: 223-229.
    • (2004) Curr. Opin. Cell Biol , vol.16 , pp. 223-229
    • Murchison, E.P.1    Hannon, G.J.2
  • 23
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison, P.J., Caudy, A.A., Bernstein, E., Hannon, G.J., and Conklin, D.S. 2002. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes & Dev. 16: 948-958.
    • (2002) Genes & Dev , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 25
    • 35548971658 scopus 로고    scopus 로고
    • MicroRNA-206 colocalizes with ribosome-rich regions in both the nucleolus and cytoplasm of rat myogenic cells
    • Politz, J.C., Zhang, F., and Pederson, T. 2006. MicroRNA-206 colocalizes with ribosome-rich regions in both the nucleolus and cytoplasm of rat myogenic cells. Proc. Natl. Acad. Sci. 103: 18957-18962.
    • (2006) Proc. Natl. Acad. Sci , vol.103 , pp. 18957-18962
    • Politz, J.C.1    Zhang, F.2    Pederson, T.3
  • 28
    • 0034767753 scopus 로고    scopus 로고
    • Antiviral actions of interferons
    • Samuel, C.E. 2001. Antiviral actions of interferons. Clin. Microbiol. Rev. 14: 778-809.
    • (2001) Clin. Microbiol. Rev , vol.14 , pp. 778-809
    • Samuel, C.E.1
  • 29
    • 33845965708 scopus 로고    scopus 로고
    • Interactions between the RNA interference effector protein Ago1 and 14-3-3 proteins: Consequences for cell cycle progression
    • Stoica, C., Carmichael, J.B., Parker, H., Pare, J., and Hobman, T.C. 2006. Interactions between the RNA interference effector protein Ago1 and 14-3-3 proteins: Consequences for cell cycle progression. J. Biol. Chem. 281: 37646-37651.
    • (2006) J. Biol. Chem , vol.281 , pp. 37646-37651
    • Stoica, C.1    Carmichael, J.B.2    Parker, H.3    Pare, J.4    Hobman, T.C.5
  • 30
    • 0037188904 scopus 로고    scopus 로고
    • The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans
    • Tabara, H., Yigit, E., Siomi, H., and Mello, C.C. 2002. The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans. Cell 109: 861-871.
    • (2002) Cell , vol.109 , pp. 861-871
    • Tabara, H.1    Yigit, E.2    Siomi, H.3    Mello, C.C.4
  • 31
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi, R., Qin, Y., Macara, I.G., and Cullen, B.R. 2003. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes & Dev. 17: 3011-3016.
    • (2003) Genes & Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 32
    • 0036074161 scopus 로고    scopus 로고
    • RNA interference in human cells is restricted to the cytoplasm
    • Zeng, Y. and Cullen, B.R. 2002. RNA interference in human cells is restricted to the cytoplasm. RNA 8: 855-860.
    • (2002) RNA , vol.8 , pp. 855-860
    • Zeng, Y.1    Cullen, B.R.2


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