Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 295, Issue 1, 2008, Pages

  Huang, Bing S ^a   White, Roselyn A ^a   Ahmad, Monir ^a   Jeng, Arco Y ^b   Leenen, Frans H H ^a  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Brain sodium; Brain steroids; Cytochrome P 450 aldosterone synthase; Diurnal variation; Hypothalamus; Mineralocorticoid receptor; Sympathoexcitation

Indexed keywords

ALDOSTERONE; ALDOSTERONE SYNTHASE; CORTICOSTERONE; FAD 286; PROTEIN INHIBITOR; SODIUM; UNCLASSIFIED DRUG; ANGIOTENSIN II; ENZYME INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE MEASUREMENT; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG EFFECT; HEART RATE; HIPPOCAMPUS; HYPERACTIVITY; HYPERTENSION; HYPOTHALAMUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ADRENERGIC SYSTEM; ANIMAL; BLOOD; BLOOD PRESSURE; BRAIN; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; WISTAR RAT;

ALDOSTERONE; ALDOSTERONE SYNTHASE; ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; BRAIN; CORTICOSTERONE; ENZYME INHIBITORS; HYPERTENSION; MALE; RATS; RATS, WISTAR; SODIUM; SYMPATHETIC NERVOUS SYSTEM;

EID: 50649107329     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.90352.2008     Document Type: Article

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