Development and validation of a liquid chromatographic method for the determination of ascorbic acid, dehydroascorbic acid and acetaminophen in pharmaceuticals

Journal of Pharmaceutical and Biomedical Analysis

Volumn 48, Issue 2, 2008, Pages 331-339

  Gioia, M G ^a   Andreatta, P ^b   Boschetti, S ^b   Gatti, R ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b E Pharma Trento SpA   (Italy)

Author keywords

4,5 Dimethyl 1,2 phenylendiamine (DMPD); Acetaminophen; Ascorbic acid (AA); Dehydroascorbic acid (DHA); Pharmaceuticals; Reversed phase liquid chromatography (RP LC); Validation

Indexed keywords

4,5 DIMETHYL 1,2 PHENYLENEDIAMINE; ASCORBIC ACID; CETRIMIDE; DEHYDROASCORBIC ACID; EDETIC ACID; PARACETAMOL; PHENYLENEDIAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; DERIVATIZATION; DRUG DETERMINATION; DRUG STRUCTURE; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY;

ACETAMINOPHEN; ASCORBIC ACID; CHROMATOGRAPHY, LIQUID; DEHYDROASCORBIC ACID; PHENYLENEDIAMINES;

EID: 50649106840     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.01.026     Document Type: Article

References (32)

1. Sweetman S.C. Martindale-The Complete Drug Reference. 34th ed. (2005), Pharmaceutical Press, London pp. 1460-1461
2. A.H. Kibbe, Handbook of Pharmaceutical Excipients, 3rd ed., American Pharmaceutical Association, Washington and Pharmaceutical Press, London, pp. 21-26.
3. Yuan J.-P., and Chen F. J. Agric. Food Chem. 46 (1998) 5078-5082
4. Deutsch J.C., and Santhos-Kumar C.R. J. Chromatogr. A 724 (1996) 271-278
5. Deutsch J.C. J. Chromatogr. A 881 (2000) 299-307
6. Karlsen A., Blomhoff R., and Gundersen T.E. J. Chromatogr. B 824 (2005) 132-138
7. López A., Montaño A., Garcia P., and Garrido A. Food Sci. Tech. Int. 11 (2005) 199-204
8. Furusawa N. Food Control 12 (2001) 27-29
9. Hernández Y., Lobo M.G., and González M. Food Chem. 96 (2006) 654-664
10. Esteve M.J., Farré R., Frigola A., and Garcia-Cantabella J.M. J. Chromatogr. B 688 (1997) 345-349
11. Shephard A.B., Nichols S.C., and Braithwaite A. Talanta 48 (1999) 585-593
12. Romeu-Nadal M., Morera-Pons S., Castellote A.I., and López-Sabater M.C. J. Chromatogr. B 830 (2006) 41-46
13. Gibbons E., Allowood M.C., Neal T., and Hardy G. J. Pharm. Biomed. Anal. 25 (2001) 605-611
14. Wechtersbach L., and Cigić B. J. Biochem. Biophys. Methods 70 (2007) 767-772
15. Pappa-Louisi A., and Pascalidou S. Anal. Biochem. 263 (1998) 176-182
16. Chinnici F., Spinabelli U., Riponi C., and Amati A. J. Food Composit. Anal. 18 (2005) 121-130
17. Ito T., Murata H., Yasui Y., Matsui M., Sakai T., and Yamauchi K. J. Chromatogr. B 667 (1995) 355-357
18. Koshiishi I., Mamura Y., Liu J., and Imanari T. Biochim. Biophys. Acta 1425 (1998) 209-214
19. Koshiishi I., Mamura Y., and Imanari T. J. Chromatogr. A 806 (1998) 340-344
20. Simoẽs S.I.D., Eleutério C.V., Cruz M.E.M., Corvo M.L., and Martins M.B.F. Eur. J. Pharm. Sci. 18 (2003) 185-189
21. Kmetec V. J. Pharm. Biomed. Anal. 10 (1992) 1073-1076
22. Kall M.A., and Andersen C. J. Chromatogr. B 730 (1999) 101-111
23. Tauz M., Kranner I., and Grill D. Phytochem. Anal. 7 (1996) 69-72
24. Keating R.W., and Haddad P.R. J. Chromatogr. 245 (1982) 249-255
25. Davey M.W., Bauw G., and Van Montagu M. J. Chromatogr. B 697 (1997) 269-276
26. Akay C., Gumesel B., Degim T., Tartilmis S., and Cevheroglu S. Drug Metabol. Drug Interact. 15 (1999) 197-205
27. Thomas B.R., Fang X.G., Shen P., and Ghodbane S. J. Pharm. Biomed. Anal. 12 (1994) 85-90
28. Thomis R., Roets E., and Hoogmartens J. J. Pharm. Sci. 73 (1984) 1830-1833
29. Iglesias J., Gonzáles M.J., and Medina I. Eur. Food Res. Technol. 223 (2006) 781-786
30. Shephard A.B., Nichols S.C., and Braithwaite A. Talanta 48 (1999) 595-606
31. Kim W.-S., Dahlgren R.L., Moroz L.L., and Sweedler J.V. Anal. Chem. 74 (2002) 5614-5620
32. The United States Pharmacopeia, Twenty-Eighth Revision-The National Formulatory, 23rd ed. United States Pharmacopeial Convention, Rockville, MD, 2005, pp. 18-19, 178-179.