Influence of hypercapnic vasodilation on cerebrovascular autoregulation and pial arteriolar bed resistance in piglets

Journal of Applied Physiology

Volumn 105, Issue 1, 2008, Pages 152-157

  Narayanan, Nithya ^a   Leffler, Charles W ^b   Daley, Michael L ^a  

^a University of Memphis ^*  (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Cerebrovascular pressure transmission; Cerebrovascular resistance

Indexed keywords

VASOPRESSIN; VASOCONSTRICTOR AGENT; VASOPRESSIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTERY RESISTANCE; ARTICLE; AUTOREGULATION; BIOMECHANICS; BRAIN BLOOD VESSEL; CONTROLLED STUDY; HYPERCAPNIA; HYPERTENSION; NEUROTRANSMISSION; NONHUMAN; PIA ARTERY; PIGLET; PRIORITY JOURNAL; VASODILATATION; ALGORITHM; ANIMAL; BIOLOGICAL MODEL; BLOOD GAS ANALYSIS; BLOOD PRESSURE; BRAIN CIRCULATION; HOMEOSTASIS; PATHOPHYSIOLOGY; PHYSIOLOGY; STATISTICAL MODEL; SWINE; VASCULAR RESISTANCE;

ALGORITHMS; ANIMALS; ARTERIOLES; BIOMECHANICS; BLOOD GAS ANALYSIS; BLOOD PRESSURE; CEREBROVASCULAR CIRCULATION; HOMEOSTASIS; HYPERCAPNIA; MODELS, BIOLOGICAL; MODELS, STATISTICAL; SWINE; VASCULAR RESISTANCE; VASOCONSTRICTOR AGENTS; VASODILATION; VASOPRESSINS;

EID: 50649094290     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00988.2007     Document Type: Article

References (28)

1. Agarwal GC, Berman BM, Stark L. A lumped parameter model of the cerebrospinal fluid system. IEEE Trans Biomed Eng 16: 45-53, 1969.
2. Barbeito A, Mark JB. Arterial and central venous pressure monitoring. Anesthesiol Clin 24: 717-735, 2006.
3. Blaha M, Aaslid R, Douvile C, Correra R, Newel D. Cerebral blood flow and dynamic cerebral autoregulation during ethanol intoxication and hypercapnia. J Clin Neurosci 10: 195-198, 2003.
4. Croinin DO, Chonghaile MN, Higgins B, Laffey JG. Bench-to-bedside review: permissive hypercapnia. Crit Care 9: 51-59, 2005.
5. Czosnyka M, Piechnik P, Richards HK, Kirpatrick P, Smielewski P, Pickard JD. Contribution of mathematical modeling to the interpretation of bedside tests of cerebrovascular autoregulation. J Neurol Neurosurg Psychiatry 63: 721-731, 1997.
6. Daley ML, Leffler CW, Czosnyka M, Pickard JD. ICP monitoring: modeling cerebrovascular pressure transmission. Acta Neurochir Suppl (Wien) 96: 103-107, 2006.
7. Daley ML, Pourcyrous M, Timmons SD, Leffler CW. Mode changes of cerebrovascular pressure transmission induced by cerebral vasodilation. J Neurotrauma 24: 559-566, 2007.
8. Daley ML, Pourcyrous M, Timmons SD, Leffler CW. Assessment of cerebrovascular autoregulation: changes of highest modal frequency of cerebrovascular pressure transmission with cerebral perfusion pressure. Stroke 35: 1952-1956, 2004.
9. Frank PT, Arthur ML, Aaslid R, David WN. Comparison of static and dynamic cerebral autoregulation measurements. Stroke 26: 1014-1019, 1995.
10. Fung YC. Biomechanics. New York: Springer, 1996, p. 11.
11. Harper AM. Autoregulation of cerebral blood flow: influence of the arterial blood pressure on blood flow through the cerebral cortex. J Neurol Neurosurg Psychiatry 29: 398-403, 1966.
12. Harper AM, Glass HI. Effect of alterations in the arterial carbon dioxide tension on the blood flow through the cerebral cortex at normal and low arterial blood pressures. J Neurol Neurosurg Psychiatry 28: 449-452, 1965.
13. Kaiser JR, Gaus HC, Williams DK. The effects of hypercapnia on cerebral autoregulation in ventilated low birth weight infants. Pediatr Res 58: 931-935, 2005.
14. Kavanagh BP, Laffey JG. Hypercapnia: permissive and therapeutic. Minerva Anestesiol 72: 567-576, 2006.
15. Kleinman B, Powell S, Kumar P, Gardner RM. The fast flush test measures the dynamic response of the entire blood pressure monitoring system. Anesthesiology 77: 1215-20, 1992.
16. Kregenow DA, Swenson ER. The lung and carbon dioxide: implications for permissive and therapeutic hypercapnia. Eur Respir J 20: 6-11, 2002.
17. Ljung L. System Identification Toolbox User's Guide. Natick, MA: MathWorks, 1991, p. 8-9.
18. Panerai RB, Kelsall AW, Rennie JM, Evans DH. Analysis of cerebral blood flow autoregulation in neonates. IEEE Trans Biomed Eng 43: 779-788, 1996.
19. Parolla DI, Beer G. Autoregulatory responses of cerebral blood vessels in hypercapnia. Isr J Med Sci 11: 469-475, 1975.
20. Pasley RL, Leffler CW, Daley ML. Modeling modulation of intracranial pressure by variation of cerebral venous resistance induced by ventilation. Ann Biomed Eng 31: 1-8, 2003.
21. Pryds A, Tonnesen J, Pryds O, Knudsen G, Greisen G. Cerebral pressure autoregulation and vasoreactivity in the newborn rat. Pediatr Res 57: 294-298, 2005.
22. Ramsay SC, Murphy K, Shea SA, Friston KJ, Lammertsma AA, Clark JC, Adams L, Guz A, Frackowiak RSJ. Changes in global cerebral blood flow in humans: effect on regional cerebral blood flow during a neural activation task. J Physiol 471: 521-534, 1993.
23. Shibata M, Einhaus S, Schweitzer JB, Zuckerman S, Leffler CW. Cerebral blood flow decreased by adrenergic stimulation of cerebral vessels in anesthetized newborn pigs with traumatic brain injury. J Neurosurg 79: 696-704, 1993.
24. Sliwka W, Krasney JA, Simon SG, Schmidth P, Noth J. Effects of sustained low-level elevations of carbon dioxide on cerebral blood flow and autoregulation of the intracerebral arteries in humans. Aviat Space Environ Med 69: 299-306, 1998.
25. Stonestreet BS, Barefield ES, Piva D, Goldstein M. Effects of hypercarbia on autoregulation of brain blood flow and cerebral metabolism in newborn piglets. Reprod Fertil Dev 7: 1381-1387, 1995.
26. Ursino M. A mathematical study of human intracranial hydrodynamics. I. The cerebrospinal fluid pulse pressure. Ann Biomed Eng 16: 379-401, 1988.
27. Ursino M, Lezzi M, Stocchetti N. Intracranial pressure dynamics in patients with acute brain damage: a critical analysis with the aid of a mathematical model. IEEE Trans Biomed Eng 42: 529-540, 1995.
28. Ursino M, Lodi CA. A simple mathematical model of the interaction between intracranial pressure and cerbral hemodynamics. J Appl Physiol 82: 1256-1269, 1997.