Serotonin syndrome triggered by a single dose of suboxone

American Journal of Emergency Medicine

Volumn 26, Issue 7, 2008, Pages 840.e3-840.e5

  Isenberg, Derek ^a   Wong, Stella C ^a   Curtis, John A ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; BENZATROPINE; BUPRENORPHINE PLUS NALOXONE; CEFTRIAXONE; CYPROHEPTADINE; DIPHENHYDRAMINE; DOXAZOSIN; DOXEPIN; ETOMIDATE; FLUTICASONE; GABAPENTIN; HYDROMORPHONE; IBUPROFEN; INSULIN; METFORMIN; METHADONE; MORPHINE; RAMIPRIL; REPAGLINIDE; TOLTERODINE; VANCOMYCIN;

ADULT; AGITATION; ARTICLE; CASE REPORT; CLONUS; DRUG INDICATION; EMERGENCY WARD; HUMAN; MALE; MENTAL HEALTH; OPIATE ADDICTION; PRIORITY JOURNAL; SELF MEDICATION; SEROTONIN SYNDROME; SIDE EFFECT; SINGLE DRUG DOSE;

EID: 50549104771     PISSN: 07356757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajem.2008.01.039     Document Type: Article

References (18)

1. http://www.fda.gov/cder/drug/infopage/subutex_suboxone [Accessed June 25, 2007].
2. http://www.fda.gov/cder/drug/infopage/subutex_suboxone [Accessed June 25, 2007].
3. Lai M.W., Klein-Schwartz W., Rodgers G.C., Abrams J.Y., Haber D.A., Bronstein A.C., et al. 2005 Annual Report of the American Association of Poison Control Centers' national poisoning and exposure database. Clin Toxicol 44 6-7 (2006) 803-932
4. Hegerl U., Bottlender R., Gallinat J., Kuss H.J., Ackenheil M., and Moller H.J. The serotonin syndrome scale: first results on validity. Eur Arch Psychiatry Clin Neurosci 248 2 (1998) 96-103
5. Kaneda Y., Ohmori T., and Fujii A. The serotonin syndrome: investigation using the Japanese version of the Serotonin Syndrome Scale. Psychiatry Res 105 1-2 (2001) 135-142
6. Boyer E.W., and Shannon M. The serotonin syndrome. N Engl J Med 352 11 (2005) 1112-1120
7. Bush E., Miller C., and Friedman I. A case of serotonin syndrome and mutism associated with methadone. J Palliat Med 9 6 (2006) 1257-1259
8. Mittino D., Mula M., and Monaco F. Serotonin syndrome associated with tramadol-sertraline co-administration. Clin Neuropharmacol 27 3 (2004) 150-151
9. Dougherty J.A., Young H., and Shafi T. Serotonin syndrome induced by amitriptyline, meperidine, and venlafaxine. Ann Pharmacother 36 10 (2002) 1647-1648
10. Houlihan D.J. Serotonin syndrome resulting from co-administration of tramadol, venlafaxine, and mirtazapine. Ann Pharmacother 38 3 (2004) 411-413
11. Kitson R., and Carr B. Tramadol and severe serotonin syndrome. Anaesthesia 60 9 (2005) 934-935
12. Gillman P.K. Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. Br J Anaesth 95 4 (2005) 434-441
13. Karunatilake H., and Buckley N.A. Serotonin syndrome induced by fluvoxamine and oxycodone. Ann Pharmacother 40 1 (2006) 155-157
14. Rosebraugh C.J., Flockhart D.A., Yasuda S.U., and Woosley R.L. Visual hallucination and tremor induced by sertraline and oxycodone in a bone marrow transplant patient. J Clin Pharmacol 41 2 (2001) 224-227
15. Gnanadesigan N., Espinoza R.T., Smith R., Israel M., and Reuben D.B. Interaction of serotonergic antidepressants and opioid analgesics: is serotonin syndrome going undetected?. J Am Med Dir Assoc 6 4 (2005) 265-269
16. Hiyama T., Shintani S., Tsutsui M., and Yasuda Y. Analgesic and narcotic antagonist effects of buprenorphine (author's translation). Nippon Yakurigaku Zasshi 79 3 (1982) 147-162
17. Tao R., Ma Z., and Auerbach S.B. Alteration in regulation of serotonin release in rat dorsal raphe nucleus after prolonged exposure to morphine. J Pharmacol Exp Ther 286 1 (1998) 481-488
18. Jolas T., and Aghajanian G.K. Opioids suppress spontaneous and NMDA-induced inhibitory postsynaptic currents in the dorsal raphe nucleus of the rat in vitro. Brain Res 755 2 (1997) 229-245