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Volumn 20, Issue 5, 2008, Pages 607-613

Relevance of MICA and other non-HLA antibodies in clinical transplantation

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HLA ANTIBODY; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 8; MAJOR HISTOCOMPATIBILITY ANTIGEN; MHC CLASS I RELATED CHAIN A; MHC CLASS I RELATED CHAIN B; PADGEM PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 50549091700     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2008.07.005     Document Type: Review
Times cited : (58)

References (58)
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    • This study demonstrates that non-HLA Abs too can be pathogenic. Passive antibody transfer induced vasculopathy and hypertension in a rat kidney-transplantation model.
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    • Identification of MICA as a new polymorphic alloantigen recognized by antibodies in sera of organ transplant recipients
    • This study for the first time demonstrated that polymorphic, MICA molecules are expressed at the cell surface of endothelial cells and may thus act as target molecules for antibodies in allograft rejection.
    • Zwirner N.W., Marcos C.Y., Mirbaha F., Zou Y., and Stastny P. Identification of MICA as a new polymorphic alloantigen recognized by antibodies in sera of organ transplant recipients. Human Immunol 61 (2000) 917-924. This study for the first time demonstrated that polymorphic, MICA molecules are expressed at the cell surface of endothelial cells and may thus act as target molecules for antibodies in allograft rejection.
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    • Introduction: MICA/MICB in innate immunity, adaptive immunity, autoimmunity, cancer, and in the immune response to transplants
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    • This study shows a clear clinical correlation between the presence of preformed MICA antibodies and early immunological complications in the absence of donor-specific HLA antibodies.
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    • Antibodies against MICA antigens and kidney-transplant rejection
    • A large study reporting the association of MICA antibodies with increased graft loss among recipients well matched for HLA.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.