Effects of delayed brain-derived neurotrophic factor application on cochlear pathology and auditory physiology in rats

Chinese Medical Journal

Volumn 121, Issue 13, 2008, Pages 1189-1196

  Song, Bing Nan ^a,b,c   Li, Yong Xin ^a,b,c   Han, De Min ^a,b,c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c BEIJING INSTITUTE OF OTOLARYNGOLOGY   (China)

Author keywords

Brain derived neurotrophic factor; Electrically evoked auditory brainstem response; Spiral ganglion cell

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; RECOMBINANT PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ELECTRODE; EVOKED BRAIN STEM AUDITORY RESPONSE; HEARING IMPAIRMENT; INNER EAR DISEASE; MALE; NONHUMAN; OUTCOME ASSESSMENT; PERIKARYON; PERILYMPH; RAT; SPINAL GANGLION; THERAPY DELAY; TREATMENT DURATION; ANIMAL; CYTOLOGY; SPIRAL GANGLION; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL SURVIVAL; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; MALE; RATS; RATS, SPRAGUE-DAWLEY; SPIRAL GANGLION;

EID: 50549090396     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200807010-00008     Document Type: Article

References (24)

1. Shepherd RK, Robert LA. Paolini AG. Long-term sensorineural hearing loss induces functional changes in the rat auditory nerve. Eur J Neurosci 2004; 20: 3131-3140.
2. Ylikoski J, Pirvola U, Moshnyakov M, Palgi J, Arumäe U, Saarma M. Expression patterns of neurotrophin and their receptor mRNAs in the rat inner ear. Hear Res 1993; 65: 69-78.
3. Lefebvre PP, Weber T, Rigo JM, Staecker H, Moonen G, Van De, et al. Peripheral and central target-derived trophic factor(s) effects on auditory neurons. Hear Res 1992; 58: 185-192.
4. Gillespie LN, Clark GM, Bartlett PF, Marzella PL. BDNF-induced survival of auditory neurons in vivo: Cessation of treatment leads to accelerated loss of survival effects. J Neurosci Res 2003; 71: 785-790.
5. Ylikoski J, Pirvola U, Virkkala J, Suvanto P, Liang XQ, Magal E, et al. Guinea pig auditory neurons are protected by Glial cell line-derived growth factor from degeneration after noise trauma. Hear Res 1998; 124: 17-26.
6. Lawner BE, Harding GW, Bohne BA. Time course of nerve-fiber regeneration in the noise-damaged mammalian cochlea. Int J Dev Neurosci 1997; 15: 601-617.
7. Puel JL, Saffiedine S, Gervais d'Aldin C, Eybalin M, Pujol R. Synaptic regeneration and functional recovery after excitotoxic injury in the guinea pig cochlea. C R Acad Sci III 1995; 318: 67-75.
8. Webster DB, Webster M. Multipolar spiral ganglion neurons following organ of Corti loss. Brain Res 1982; 244: 356-359.
9. Imamura SI, Adams JC. Changes in cytochemistry of sensory and nonsensory cells in gentamicin-treated cochleas. J Assoc Res Otolaryngol 2003; 4: 196-218.
10. Brown JN, Miller JM, Altschuler RA, Nuttall AL. Osmotic pump implant for chronic infusion of drugs into the inner ear. Hear Res 1993; 70: 167-172.
11. Miller JM, Le Prell CG, Prieskorn DM, Wys NL, Altschuler RA. Delayed neurotrophin treatment following deafness rescues spiral ganglion cells from death and promotes regrowth of auditory nerve peripheral processes: effects of brain-derived neurotrophic factor and fibroblast growth factor. J Neurosci Res 2007; 85: 1959-1969.
12. Wise AK, Richardson R, Hardman J, Clark G, O'leary S. Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3. J Comp Neurol 2005; 487: 147-165.
13. Terenghi G. Peripheral nerve regeneration and neurotrophic factors. J Anat 1999; 194: 1-14.
14. Gillespie LN, Clark GM, Bartlett PF, Marzella PL. LIF is more potent than BDNF in promoting neurite outgrowth of mammalian auditory neurons in vitro. Neuroreport 2001; 12: 275-279.
15. Otte J, Schuknecht HF, Kerr AG. Ganglion cell populations in normal and pathological human cochleae: implication for cochlear implantation. Laryngoscope 1978; 88: 1231-1246.
16. Miller JM, Altschuler RA. Effectiveness of different electrical stimulation conditions in preservation of spiral ganglion cells following deafness. Ann Otol Rhinol Laryngol 1995 Suppl; 166: 57-60.
17. Leake PA, Hradek GT, Snyder RL. Chronic electrical stimulation by a cochlear implant promotes survival of spiral ganglion neurons after neonatal deafness. J Comp Neurol 1999; 412: 543-562.
18. Gillespie LN, Clark GM, Marzella PL. Delayed neurotrophin treatment supports auditory neuron survival in deaf guinea pigs. Neuroreport 2004; 15: 1121-1125.
19. Richardson RT, O'Leary S, Wise A, Hardman J, Clark G. A single dose of neurotrophin-3 to the cochlea surrounds spiral ganglion neurons and provides trophic support. Hear Res 2005; 204: 37-47.
20. Yamagata T, Miller JM, Ulfendahl M, Olivius NP, Altschuler RA, Pyykkö I, et al. Delayed neurotrophic treatment preserves nerve survival and electrophysiological responsiveness in neomycin-deafened guinea pigs. J Neurosci Res 2004; 78: 75-86.
21. Shinohara T, Bredberg G, Ulfendahl M, Pyykkö I, Olivius NP, Kaksonen R, et al. Neurotrophic factor intervention restores auditory function in deafened animals. Proc Natl Acad Sci U S A 2002; 99: 1657-1660.
22. Shepherd RK, Coco A, Epp SB, Crook JM. Chronic depolarization enhances the trophic effects of brain-derived neurotrophic factor in rescuing auditory neurons following a sensorineural hearing loss. J Comp Neural 2005; 486: 145-158.
23. Shepherd RK, Xu J. A multichannel scala tympani electrode array incorporating a drug delivery system for chronic intracochlear infusion. Hear Res 2002; 172: 92-98.
24. Kanzaki S, Stöver T, Kawamoto K, Prieskorn DM, Altschuler RA, Miller JM, et al. Glial cell line-derived neurotrophic factor and chronic electrical stimulation prevent VIII cranial nerve degeneration following denervation. J Comp Neurol 2002; 454: 350-360.