Establishment of hyperuricemia rat model with different doses of hypoxanthine and oxonic acid potassium salt

Chinese Journal of Pharmacology and Toxicology

Volumn 22, Issue 4, 2008, Pages 306-310

  Xu, Li ^a   Shi, Le ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Hyperuricemia; Hypoxanthine; Models, animal; Oxonic acid potassium salt; Uricase inhibitor

Indexed keywords

HYPOXANTHINE; OXONIC ACID; OXONIC ACID POTASSIUM SALT; POTASSIUM SALT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE MODEL; DOSE RESPONSE; GOUT; HYPERURICEMIA; NONHUMAN; RAT; UREA NITROGEN BLOOD LEVEL; URIC ACID BLOOD LEVEL;

ANIMALIA; RATTUS;

EID: 50449107644     PISSN: 10003002     EISSN: None     Source Type: Journal    
DOI: 10.3867/j.issn.1000-3002.2008.04.011     Document Type: Article

References (5)

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2. Xu L, Shi L, Zhao F, Tan QW, Yao JL. A preliminary study on the establishment of rat model with acute hyperuricemia[J]. Chin Pharmacol Bull, 2007, 23(7):976-978.
3. Xu L, Shi L, Zhong WX. Exploratory development of uricase inhibitor for replicating acute animal model of hyperuricemia on rat[ J]. Chin J Comp Med, 2007, 17(3):142-146.
4. Yin W. Hyperuricemia and gout[J]. J Postgrad Med, 1998, 21(11):573-575.
5. Wang HY. Nephrology [M]//2nd ed, Beijing: People's Medical Publishing House, 1996:974.