Maternal thyroid hormone: A strong repressor of neuronal nitric oxide synthase in rat embryonic neocortex

Endocrinology

Volumn 149, Issue 9, 2008, Pages 4396-4401

  Sinha, Rohit Anthony ^a   Pathak, Amrita ^a   Mohan, Vishwa ^a   Bandyopadhyay, Sanghamitra ^b   Rastogi, Leena ^a   Godbole, Madan M ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN 2; NEURONAL NITRIC OXIDE SYNTHASE; THYROID HORMONE; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; EMBRYO; ENZYME REPRESSION; HORMONE ACTION; HORMONE TRANSPORT; HYPOTHYROIDISM; IMMUNOBLOTTING; IMMUNOREACTIVITY; NEOCORTEX; NERVE CELL NECROSIS; NONHUMAN; PRENATAL SCREENING; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT;

ANIMALS; CELL DEATH; CONGENITAL HYPOTHYROIDISM; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MATERNAL-FETAL RELATIONS; NEOCORTEX; NITRIC OXIDE SYNTHASE TYPE I; PHOSPHOPROTEIN PHOSPHATASES; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; THYROID HORMONES;

EID: 50449102363     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-1617     Document Type: Article

References (36)

1. Haddow JE, Palomaki GE, Allan WC, Williams JR, Knight GJ, Gagnon J, O'Heir CE, Mitchell ML, Hernos RJ, Waisbren SE, Faix JD, Klein RZ 1999 Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. N Engl J Med 341:549-555
2. Davies TF 2007 Time for the American thyroid association to lead on thyroid screening in pregnancy. Thyroid 17:697-698
3. Morreale de Escobar G, Obregon, MJ, Escobar del Rey F 2004 Role of thyroid hormone during early brain development. Eur J Endocrinol 151 Suppl 3:U25-U37
4. Auso E, Lavado-Autric R, Cuevas E, del Rey FE, Morreale de Escobar G, Berbel P 2004 A moderate and transient deficiency of maternal thyroid function at the beginning of fetal neocorticogenesis alters neuronal migration. Endocrinology 145:4037-4047
5. Zoeller RT, Rovet J 2004 Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings. J Neuroendocrinol 16:809-818
6. Dowling AL, Martz GU, Leonard JL, Zoeller RT 2000 Acute changes in maternal thyroid hormone induce rapid and transient changes in gene expression in fetal rat brain. J Neurosci 20:2255-2265
7. Dowling AL, Iannacone EA, Zoeller RT 2001 Maternal hypothyroidism selectively affects the expression of neuroendocrine-specific protein A messenger ribonucleic acid in the proliferative zone of the fetal rat brain cortex. Endocrinology 142:390-399
8. Sampson D, Pickard MR, Sinha AK, Evans IM, Leonard AJ, Ekins RP 2000 Maternal thyroid status regulates the expression of neuronal and astrocytic cytoskeletal proteins in the fetal brain. J Endocrinol 167:439-445
9. Dowling AL, Zoeller RT 2000 Thyroid hormone of maternal origin regulates the expression of RC3/neurogranin mRNA in the fetal rat brain. Brain Res Mol Brain Res 82:126-132
10. Pickard MR, Sinha AK, Ogilvie LM, Leonard AJ, Edwards PR, Ekins RP 1999 Maternal hypothyroxinemia influences glucose transporter expression in fetal brain and placenta. J Endocrinol 163:385-394
11. Bansal R, You SH, Herzig CT, Zoeller RT 2005 Maternal thyroid hormone increases HES expression in the fetal rat brain: an effect mimicked by exposure to a mixture of polychlorinated biphenyls (PCBs). Brain Res Dev Brain Res 156:13-22
12. Bradley DJ, Towle HC, Young WS 1992 Spatial and temporal expression of α- and β-thyroid hormone receptor mRNAs, including the β2-subtype, in the developing mammalian nervous system. J Neurosci 12:2288-2302
13. Samdani AF, Newcamp C, Resink A, Facchinetti F, Hoffman BE, Dawson VL, Dawson TM 1997 Differential susceptibility to neurotoxicity mediated by neurotrophins and neuronal nitric oxide synthase. J Neurosci 17:4633-4641
14. Serfozo Z, Kiss PB, Kukor Z, Lontay B, Palatka K, Varga V, Erdodi F, Elekes K 2008 Thyroid hormones affect the level and activity of nitric oxide synthase in rat cerebral cortex during postnatal development. Neurochem Res 33:569-578
15. Gingerich S, Krukoff TL 2005 Estrogen modulates endothelial and neuronal nitric oxide synthase expression via an estrogen receptor β-dependent mechanism in hypothalamic slice cultures. Endocrinology 146:2933-2941
16. -ΔΔCT method. Methods 25:402-408
17. Terada H, Nagai T, Kimura H, Kitahama K, Okada S 1996 Distribution of nitric oxide synthase-immunoreactive neurons in fetal rat brains at embryonic day 15 and day 19. J Chem Neuroanat 10:273-278
18. Cheng A, Wang S, Cai J, Rao MS, Mattson MP 2003 Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain. Dev Biol 258:319-333
19. Fritzen S, Schmitt A, Köth K, Sommer C, Lesch KP, Reif A 2007 Neuronal nitric oxide synthase (NOS-I) knockout increases the survival rate of neural cells in the hippocampus independently of BDNF. Mol Cell Neurosci 35:261-271
20. Bonfoco E, Zhivotovsky B, Rossi AD, Aguilar-Santelises M, Orrenius S, Lipton SA, Nicotera P 1996 BCL-2 delay apoptosis and PARP cleavage induced by NO donors in GT1-7 cells. Neuroreport 8:273-276
21. Tiwari BD, Godbole MM, Chattopadhyay N, Mandal A, Mittal A 1996 Learning disabilities and poor motivation to achieve due to prolonged iodine deficiency. Am J Clin Nutr 63:782-786
22. Becker DV, Braverman LE, Delange F, Dunn JT, Franklyn JA, Hollowell JG, Lamm SH, Mitchell ML, Pearce E, Robbins J, Rovet JF 2006 Iodine supplementation for pregnancy and lactation-United States and Canada: recommendations of the American Thyroid Association. Thyroid 16:949-951
23. Vermiglio F, Lo Presti VP, Moleti M, Sidoti M, Tortorella G, Scaffidi G, Castagna MG, Mattina F, Violi MA, Crisà A, Artemisia A, Trimarchi F 2004 Attention deficit and hyperactivity disorders in the offspring of mothers exposed to mild-moderate iodine deficiency: a possible novel iodine deficiency disorder in developed countries. J Clin Endocrinol Metab 89:6054-6060
24. Esplugues JV 2002 NO as a signalling molecule in the nervous system. Br J Pharmacol 135:1079-1095
25. Petzold GC, Scheibea F, Brauna JS, Freyera D, Prillera J, Dirnagla U, Dreiera JP 2005 Nitric oxide modulates calcium entry through P/Q-type calcium channels and N-methyl-d-aspartate receptors in rat cortical neurons. Brain Res 1063:9-14
26. Contestabile A 2000 Roles of NMDA receptor activity and nitric oxide production in brain development. Brain Res Brain Res Rev 32:476-509
27. Bredt DS, Snyder SH 1994 Transient nitric oxide synthase neurons in embryonic cerebral plate, sensory ganglia, and olfactory epithelium. Neuron 13:301-313
28. Morte B, Manzano J, Scanlan T, Vennström B, Bernal J 2002 Deletion of thyroid hormone receptor α 1 prevents the structural alterations of the cerebellum induced by hypothyroidism. Proc Natl Acad Sci USA 99:3985-3989
29. Wallis K, Sjögren M, van Hogerlinden M, Silberberg G, Fisahn A, Nordström K, Larsson L, Westerblad H, Morreale de Escobar G, Shupliakov O, Vennström B 2008 Locomotor deficiencies and aberrant development of subtype-specific GABAergic interneurons caused by an unliganded thyroid hormone receptor α1. J Neurosci 28:1904-1915
30. Hiroi Y, Kim HH, Ying H, Furuya F, Huang Z, Simoncini T, Noma K, Ueki K, Nguyen NH, Scanlan TS, Moskowitz MA, Cheng SY, Liao JK 2006 Rapid nongenomic actions of thyroid hormone. Proc Natl Acad Sci USA 103:14104-14109
31. Gothe S, Wang Z, Ng L, Kindblom JM, Barros AC, Ohlsson C, Vennstrom B, Forrest D 1999 Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation. Genes Dev 13:1329-1341
32. Munoz A, Wrighton C, Seliger B, Bernal, J, Beug H 1993 Thyroid hormone receptor/c-erbA: control of commitment and differentiation in the neuronal/chromaffin progenitor line PC12. J Cell Biol 121:423-438
33. Lavado-Autric R, Auso E, Garcia-Velasco JV, Arufe Mdel C, del Rey FE, Berbel P, Morreale de Escobar G 2003 Early maternal hypothyroxinemia alters histogenesis and cerebral cortex cytoarchitecture of the progeny. J Clin Invest 111:1073-1082
34. Goodman JH, Gilbert ME 2007 Modest thyroid hormone insufficiency during development induces a cellular malformation in the corpus callosum: a model of cortical dysplasia. Endocrinology 148:2593-2597
35. Morreale de Escobar G, Obregon MJ, Escobar del Rey F 2000 Is neuropsychological development related to maternal hypothyroidism or to maternal hypothyroxinemia? J Clin Endocrinol Metab 85:3975-3987
36. Berbel P, Obregón MJ, Bernal J, Rey FE, Escobar GM 2007 Iodine supplementation during pregnancy: a public health challenge. Trends Endocrinol Metab 18:338-343