The impact of duration of organ dysfunction on the outcome of patients with severe sepsis and septic shock

Clinics

Volumn 63, Issue 4, 2008, Pages 483-488

  Freitas, Flávio G R ^a   Salomão, Reinaldo ^a   Tereran, Nathalia ^a   Mazza, Bruno Franco ^a   Assunção, Murillo ^a   Jackiu, Mirian ^a   Fernandes, Haggeas ^a   Machado, Flávia Ribeiro ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Infection; Intensive care; Sepsis diagnosis; Sepsis management; Surviving sepsis campaign

Indexed keywords

APACHE; ARTICLE; BRAZIL; FEMALE; GLUCOSE BLOOD LEVEL; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; MALE; MIDDLE AGED; MORTALITY; MULTIPLE ORGAN FAILURE; ONSET AGE; RETROSPECTIVE STUDY; SEPSIS; SEPTIC SHOCK; STATISTICS; SURVIVAL; TIME; TREATMENT OUTCOME;

AGE OF ONSET; APACHE; BLOOD GLUCOSE; BRAZIL; FEMALE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; RETROSPECTIVE STUDIES; SEPSIS; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC; SURVIVAL ANALYSIS; TIME FACTORS; TREATMENT OUTCOME;

EID: 50449093921     PISSN: 18075932     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1807-59322008000400012     Document Type: Article

References (25)

1. Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 200317;348:1546-54.
2. Vincent JL, Sakr Y, Sprung CL, Ranieri VM, Reinhart K, Gerlach H, et al. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med. 2006;34:344-53.
3. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001;29:1303-10.
4. Vincent JL, Abraham E, Annane D, Bernard G, Rivers E, Van den Berghe G. Reducing mortality in sepsis: new directions. Crit Care. 2002;6 Suppl 3:S1-18.
5. Silva E, Pedro Mde A, Sogayar AC, Mohovic T, Silva CL, Janiszewski M, et al. Brazilian Sepsis Epidemiological Study (BASES study). Crit Care. 2004;8:R251-60.
6. Sogayar AMC, Machado FR, Rea-Neto A, Dornas A, Grion C, Lobo SM, Tura B, et al. For the Costs Study Group - Latin American Sepsis Institute: COSTS - multicenter, prospective study to evaluate costs of septic patients in Brazilian intensive care units, Pharmacoeconomics, in press.
7. Teres D, Rapoport J, Lemeshow S, Kim S, Akhras K. Effects of severity of illness on resource use by survivors and nonsurvivors of severe sepsis at intensive care unit admission. Crit Care Med. 2002;30:2413-9.
8. Heyland DK, Hopman W, Coo H, Tranmer J, McColl MA. Long-term health-related quality of life in survivors of sepsis. Short Form 36: a valid and reliable measure of health-related quality of life. Crit Care Med. 2000;28:3599-605.
9. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001;345:1368-77.
10. van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001;345:1359-67.
11. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med. 2000;342:1301-8.
12. Annane D, Sebille V, Charpentier C, Bollaert PE, Francois B, Korach JM, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. Jama. 2002;288:862-71.
13. Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001;344:699-709.
14. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, et al. Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med. 2008;34:17-60.
15. Institute for Healthcare Improvement: Sepsis [http://www.ihi.org/IHI/ Topics/CriticalCare/Sepsis.html].
16. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992;20:864-74.
17. Poeze M, Ramsay G, Gerlach H, Rubulotta F, Levy M. An international sepsis survey: a study of doctors' knowledge and perception about sepsis. Crit Care. 2004;8:R409-13.
18. Assuncao M, Machado F, Akamine N, Cardoso G, Mello P, Telles J, et al. Do they know what is sepsis time? Septic Patients Survey Enrolling Staffs study. Critical Care. 2007;11(Suppl 2):P45.
19. Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006;34:1589-96.
20. Vincent JL, Bernard GR, Beale R, Doig C, Putensen C, Dhainaut JF, et al. Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment. Crit Care Med. 2005;33:2266-77.
21. Trzeciak S, Dellinger RP, Abate NL, Cowan RM, Stauss M, Kilgannon JH, et al. Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department. Chest. 2006;129:225-32.
22. Jones AE, Focht A, Horton JM, Kline JA. Prospective external validation of the clinical effectiveness of an emergency department-based early goal-directed therapy protocol for severe sepsis and septic shock. Chest. 2007;132:425-32.
23. Gattinoni L, Brazzi L, Pelosi P, Latini R, Tognoni G, Pesenti A, et al. A trial of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. N Engl J Med. 1995;333:1025-32.
24. Silva E, Poli de Figueiredo. Sepsis, from bench to bedside. Clinics. 2008;63:109-20.
25. Kern JW, Shoemaker WC. Meta-analysis of hemodynamic optimization in high-risk patients. Crit Care Med. 2002;30:1686-92.